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Showing 4 results for Keshavarz

Nima Rahmani, Abdollah Keshavarz, Seyed Saeed Tabatabaei, Rohollah Kalhor,
Volume 6, Issue 4 (15 2012)
Abstract

Background and Aim: In many countries, hospitals have triple ownership (governmental or public, for-profit, and not-for-profit). Numerous studies have been performed in order to investigate the differences among these hospitals in accordance to expenditures, presentation of uncompensated therapeutic services, number of outgoing patients and other measurement devices of hospital performance. The aim of this research was to investigate the role of ownership on total Factors Productivity changes in Qazvin`s selected hospitals.

Materials and Methods: Descriptive-analytic study was conducted in three periods of time from 2005 to 2007 in 8 selected hospitals of Qazvin. Inclusion criteria included the active beds and the value of intermediate consumptions in hospitals.The exclusion criteria included the total number of inpatient and surgical operations. Data collection tool, was researcher-designed checklist. Data were analyzed using DEAP 2/1 software and ANOVA, HSD and TUKEY tests.

Results: There was a significant difference between the mean productivity of three hospital groups due to the existence of various ownership(p=%012), Also a significant difference was observed between the mean of technological efficiency of the three groups of hospitals(p=%006), No significant differences was found between the mean of technical efficiency of the three groups of hospitals(p=%23).

Conclusion: Cause of the variation in total factor productivity in private hospitals, is due to their suitable production technology which is always improved. But in respect to their efficiency promotion and optimization of production and products, there was no distinguishing difference with other hospitals.


Farzad Nazem, Behzad Keshavarz,
Volume 7, Issue 2 (7-2013)
Abstract

Background and Aim: Plasma leptin, adiponectin (as theadipokines) and related obesity – HOMA index in the obese men are introduced as a predictive metabolic indicators for asthmatic individuals. However, under asthma conditions, role of cariometabolic variables interaction for altering clinical pulmonary indexes aren't clear. In the present study, the relationship between plasmatic adiponectin to leptin ratio (adipo/lep) with respiratory capacities & HOMA in the chronic asthmatic males are investigated.

Materials and Methods: Thirty nine obese males with mild to moderate asthma with an average age of 38±2.6 ys and BMI 31.4 ± 1.06 kg/m2 voluntarly participated in this study. Baseline plasmatic leptin, adiponetin, insulin and glucose levels were determined after 10-12 hours fasting overnight. FEV1/FVC, PEF% and FEF 25%-75% were determined by standard method. A pearson correlation test was used to analyse data.

Results: There were no significant correlation between WHR , BMI with metabolic risk factors (P>0.05). Relationship markedly observed among HOMA with adipo/ lep ratio and leptin levels respectively (P<0.05), Also a marked negative correlation between adipokine ratio and leptin level was obtained (P<0.05). From view of respiratory efficiency, FVC% and FEV1/ FVC were maingly corrected with baseline leptin&adiponectin levels (P<0.05).

Conclusion: Inconclusion,it seems that adipo/lep ratio biomarker plays as a clinical diagnosis index for HOMA index than baseline leptin or adiponectin levels. However, these findings showed that FEV1/FVC & adipo/lept ratios are accounted as valuable indicators for evaluating the obesity syndrome and pulmonary efficiency in the asthma disease.


Zohre Keshavarz, Masoumeh Simbar, Ali Ramezankhani , Abolghasem Pourreza, Hamid Alavi Majd ,
Volume 10, Issue 1 (4-2016)
Abstract

Background and Aim: Caring about workers is important due to protect human capital and economic growth. Understanding health priorities is one of the main challenges of health management. The aim of this research was to priorities health promotion behaviors of female workers.

Materials and Methods: This study was conducted in 2012 and had a triangulation design with sequential qualitative-quantitative method based on "integrated model of planned behavior and self-efficacy". In the qualitative phase of the study, a content analysis approach was done  to develop the questionnaire, based on the model and psychometric properties were assessed. Then, the educational intervention was conducted in an experimental study with randomized sampling in 70 female workers (35 intervention group, 35 controls). The pretest and posttest was compared.

Results: Content analysis demonstrated 6 main themes, including the main constructs of the research model: attitude, subjective norm, perceived behavioural control, self-efficacy, intention and behaviour in 4 domain (nutrition, exercise, cervical and breast cancer screening, cope with stress). Scale level content validity index was 0.93. Confirmatory factor analysis showed CFI=0.97, GFI=0.95, IFI=0.96, NNFI=0.98, NFI=0.97, RMSEA=0.05. Concurrent validity versus the Health-promoting lifestyle profile II showed r=0.60. Cronbach alpha was 0.75–0.93 across the subscales. Test–retest reliability revealed no significant differences.After educational intervention there was a significant increase in attitude, subjective norm, perceived behavioral control, self-efficacy, intention and behavior of female workers in intervention group. Also, effect of intervention program was mostly in self-efficacy construct.

Conclusion: With regards to working conditions economic and socio-cultural barriers in female workers, health policy making is essential in this group to promote health


Mohammad Mehdi Soltan Dallal, Abolfazl Keshavarz, Ebrahim Kord, Nastaran Ansari, Zamaneh Hajikhezri, Katayoun Samimi-Rad,
Volume 12, Issue 1 (5-2018)
Abstract

Background and Aim: At the present time one of the strategies in vaccine design is generation of fusion proteins containing (including) immunogen of infectious agents and adjuvants. In this study design and construction of E2-fliC fragment as a vaccine candid was conducted by using fliC gene from Salmonella enterica and E2 gene from hepatitis C virus.
Materials and Methods: To prepare the E2-fliC construct, E2 and fliC fragments were first amplified from pBluscript-E2 and pBluscript-fliC, respectively by PCR method. To generate pcDNA-E2-fliC plasmid, E2 was subcloned into plasmid pcDNA3.1 (+) which was extracted from DH5α cells. The fliC sequence was then cloned into the pcDNA3.1-E2. To evaluate the expression of E2-fliC construct, it was inserted into the pEGFP-N3 expression vector. Then COS-7 cells were transfected with pEGFPN3- E2-fliC to evaluate the expression of the fusion protein by observation of the EGFP signal under the fluorescence microscope.
Results: By development of GFP fluorescent using fluorescence microscopy the most expression of E2-fliC construct was observed at 24h after transfection. The accuracy of the recombinant plasmid pcDNA-E2-fliC was confirmed by PCR, restriction enzymes and DNA sequencing.
Conclusion: Our findings suggest that E2-FliC fusion protein has expressed efficiently and most likely similar to HCV E2 protein induces immune system of mice after their immunization with pcDNA-E2-fliC.


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