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Showing 6 results for Maleki
Comparison of Cardiovascular Diseases Classification in some developed countries with Iran
R Safdari , M Maleki , V Ghorbani ,
Volume 3, Issue 2 (21 2009)
Abstract

Background and Aim: Today, cardiovascular diseases are the most important public health challenges in the world. Prevention and management of cardiovascular diseases necessitate the existence of a comprehensive system for recording data. Patient medical document is one of the most important data which should be classified so to facilitate and expedite the treatment process. A comparison of cardiovascular disease classification systems could assist health care policy makers to battle cardiovascular diseases.

Materials and Methods: This descriptive-comparative study conducted during years 2007-2008. The cardiovascular diseases classification systems in USA, Australia, England and Canada were reviewed. Data collecting was done through literature review, Internet and e-mail.

Results : The cardiovascular disease classification systems of all the developed countries are national. The developed countries, with the exception of England, utilize a multiracial classification model, especially designed to reflect the individual requirements of every single one of them. This model employs health care standards, e-learning, annual educational programs, and consultation with experts. Iran lacks such a national classification system for cardiovascular diseases.

Discussion and Conclusion : In order to improve the management and prevention of cardiovascular diseases in Iran, it is essential that the cardiovascular disease classification system in the country be national.


Opinions of clinicians towards use of computer applications for detecting drug-food interactions
As Gharamaleki, A Ahmadi, F Faraji Khiavi, Sh Arpanahi Istadegi, K Jafarian,
Volume 5, Issue 1 (26 2011)
Abstract

Background and Aim: Adverse events in hospitals are found to be a major problem of all health systems in the world. In fact, drug interaction side effects are now the fourth leading cause of death in the U.S. The aim of the current study was to identify the opinions of clinicians working in Shariati and Emam hospitals towards the use of computer applications for detecting drug-food interactions.

Materials and Methods: Ninety clinicians including physicians, pharmacists and nurses were selected randomly in the current descriptive- analytical study. The opinions of clinicians toward using computer application systems for detecting drug-food interactions were assessed by a questionnaire. The questionnaire's validity and repeatability was examined in a pilot study. Cronbach's alpha was 0.85 which indicated an acceptable level of repeatability of the questionnaire. The questionnaire was distributed among the academic staffs in order to determine its validity.

Results: 95.4% of clinicians had positive attitudes towards the requirement of computer application to detect drug-food interactions. Around 94% of them showed their willingness towards using the computer application systems. Therefore, use of computer application seems to be necessary in health system.

Conclusions: The collection and analysis of data encourages further investments in computerized system to prevent drug-food interaction. Such built-in warning systems in hospitals alert doctors to drug-food interaction and improvement in patient care. Screening each patient's medication plan for drug-food interactions can reduce medical error and improve the quality of health care


Effect Of Food Distribiution Training On The Amount Of Food Residuals In Tehran Boali Hospital In 2010
Seyed Jamalodin Tabibi, Mohammad Reza Maleki, Mahsa Ghazi Asgar,
Volume 5, Issue 5 (7 2012)
Abstract

Background and Aim: The increase of food residuals specially in hospital can lead to a decrease in food intake and customer satisfaction and also increase the cost of remedy and hospitalization. The goal of this study was to determine the effect of food service training of food staff on the amount of food residuals to improve hospital catering.

Materials and Methods: This was cross sectional study. The study population consisted of staff and patients in orthopedic, chemotherapy and surgery wards and their relatives (n=130). The tools of this study were satisfaction survey questionnaire and food residual observational checklist. Questionnaires were completed by the study population and observational checklist by the researchers. Data were analysed using SPSS Software.

Results: Significant difference were observed between the amount of food residual before and after personnel training (t=-5/36, p=0/001).The average amount of food remaining in the breakfast from 1/8 in pre-teaching was decreased to 0/7, at lunch from 2/09 to1/89 and in dinner time from 2/2 to 1/6.

Conclusion: It seems that educational planning of personnel could increase their knowledge about their duties and weaknesses and improves quality performance which leads to customer satisfaction and hospital profitability.


Designing A Medical Errors Control Model For Tehran University Of Medical Science Hospitals
Amir Ashkan Nasiripour, Pouran Raeissi, Farhad Ghaffari, Mohhamadreza Maleki, Mehrnush Jafari,
Volume 8, Issue 1 (5-2014)
Abstract

 Background and Aim: Healthcare processes have caused many dangers to patients, and the increase of medical errors is one of the most important consequences of such processes. The present research is conducted to reduce medical errors through presenting a model to control them.

 Materials and Methods: In this mixed (quantitative-qualitative) research, a conceptual model was assembled. Then using the model and an interview, a questionnaire was made. The interview and the researcher-made questionnaire were used to collect data. The statistical population included the related people and the practitioners involved in medical errors in Tehran University of medical Sciences (TUMS) hospitals. The sample consisted of 252 employees who were non-randomly selected from those hospitals. Once the affecting factors were determined, the data were analyzed through factor analysis technique. The gathered data were analyzed using descriptive and inferential statistics. Finally, the research model was presented.

 Results: The selected individuals pointed out 9 factors controlling the medical errors: culture, factors associated with patients, factors related to providers, factors associated with errors, structural factors, role of disclosure, error registration, individual factors related to reporting, and organizational factors related to reporting. The 9 factors are the subdivisions of three main factors which account for 57/46% of the total variance of data. The most decisive power is related to disclosure 0.737 and the least (0.053) pertains to structure.

 Conclusion: Discloser of medical errors and their registration are factors which are effective and essential in controlling medical errors in TUMS hospitals.

 


The Role of Exosomes in Myeloid and Lymphoid Blood Malignancies: A Systematic Review Article
Asma Maleki, Zahra Kashani Khatib, Shaban Alizadeh, Amir Ali Hamidieh, Ali Akbar Pourfatollah,
Volume 15, Issue 2 (Jun & Jul 2021)
Abstract
Background and Aim: Blood malignancies, one of the most common cancers in the world, cause a large number of deaths each year. Many inherited and acquired factors are involved in the development of this disease. Exosomes are a very small model of cells that are secreted by most cells in the body under physiological and pathological conditions. On the other hand, they have found a special place in the treatment of these diseases because of their very small structure and biodegradability. 
Materials and Methods: This study is a systematic review article. For this study, the electronic databases such as PubMed, Scopus and Web of Science were reviewed and 110 original and review articles were studied from 2000 to 2020. Exosome, blood malignancies and immunotherapy were used as keywords along with a number of other related terms such as tumor microenvironment, acute myeloid leukemia, acute lymphoid leukemia, chronic lymphoid leukemia and multiple myeloma (Exosome AND Leukemia, Leukemia AND Immunotherapy, Exosome AND Cancer, AML AND Exosome) to search in these databases. Finally, 51 sources that related to exosomes and myeloid and lymphoid blood malignancies were used.
Results: The genomic profile of malignant cells and tumor microenvironment changes in the conditions of the disease. The contents of exosomes released by leukemic cells, including anti-apoptotic proteins, various microRNAs, angiogenic agents, heat shock proteins and oncogenes involved in the development of inflammatory phenotype in the target cells, are known as factors involved in the pathogenesis of leukemia. A variety of therapeutic materials such as anti-inflammatory drugs, recombinant proteins, siRNA and the inhibitor of various microRNAs can also be packaged in the exosomes with several ways and used to treat leukemia.
Conclusion: Exosomes derived from malignant cells play the important role in the growth and proliferation, angiogenesis, metastasis, resistance to chemotherapeutic agent, and the escape of cancer cells from the immune system by the modification of tumor microenvironment. The role of exosomes in the creation and development of blood malignancies has been proven. Therefore, using of them will probably be very helpful and promising in the treatment of these disorders with various forms.

Comparison of Duffy Blood Group System Genotype in Kurdish Patients with Beta-Thalassemia Major in Kermanshah City: A Case-Control Study
Ali Maleki, Marivan Noori, Rezvan Zomorodi, Fakhredin Saba,
Volume 16, Issue 5 (Dec 2022)
Abstract
Background and Ami: Identifying the genotype of blood groups in different communities will give the decision makers of the health system to take the necessary measures to prevent and identify the possible side effects of blood transfusion, including the production of alloantibodies. Duffy blood group has increased the possibility of alloantibody production in beta-thalassemia major patients who regularly need blood transfusion due to different types of genotype with different prevalence. However, no study has been conducted regarding the frequency of Duffy blood group distribution in beta-thalassemia Kurd patients dependent on blood transfusion.
Materials and Methods: This case-control study was conducted on 100 patients with beta thalassemia major, as case group and 50 healthy individuals, as control group, in Bostan Clinic, Kermanshah University of Medical Sciences. After collecting peripheral blood samples from people participating in the study, DNA was extracted from peripheral blood mononuclear cells. Then, using PCR-RFLP and electrophoresis, Duffy genotypes including FYA/A, FYB/B and FYA/B were identified.
Results: The results of Chi-square test showed that in the patient group, there is no statistically significant difference between the two genders in terms of the frequency of distribution of Duffy genotypes (P=0.588). On the other hand, in the healthy group too, there was no statistically significant difference between the two sexes in terms of the frequency of distribution of Duffy genotypes (P=0.707). According to nominal regression results, although the distribution ratio rate (95% confidence interval) of FYA/FYA and FYB/FYB genotypes as compared to FYA/FYB genotype (reference category) in the patient group as compared to healthy people was 2.42 (0.7 to 8.34) and 0.76 (0.36 to 1.64) respectively, but there was no statistically significant difference between the case and control groups in terms of the distribution frequency of these genotypes (P<0.05).
Conclusion: The frequency distribution of Duffy genotypes in beta-thalassemia major patients is similar to that of healthy people, and there is no relationship between the distribution of Duffy genotypes and beta-thalassemia disease. FYB genotype has the highest frequency in both case and control groups

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