Hossein Dargahi, Seyed Asghar Mir Emadi, Shahnam Sedigh Maroufi, Hamid Choobine, Cyrus Azimi, Mohammad Kazem Sharifi Yazdi,
Volume 6, Issue 2 (14 2012)
Abstract
Background and Aim: Although vancomycine is used for the treatment of methicillin resistant Staphylococci, but vancomycine alone might not be effective for the treatment of methicillin resistant Staphylococci in compromised host. In the same time antimicrobial activity of cefepim on gram positive bacteria especially Staphylococci is well known. In this study the synergism effect of cefepim and vavcomycin on positive and negative coagulase Staphylococci in vitro condition was investigated.
Materials and Methods: In total, 100 clinical samples of coagulase positive and negative Staphylococci were isolated from urine and blood samples from patients in Imam Khomeini Hospital during one year and identified .The modified Bauer-Kirby were used for the antibiotic susceptibility and macrodilution method for the MIC according to NCCLS procedure.
Results: The results showed that after adding vancomycin to cefepime in concentration from 0.05+ 0.5 , to 0.8+8 , growth reduction reached from 3.5% to 100%.The synergism effect of the two mentioned antibiotics on coagulase negative Staphylococci resistant to methicillin were shown that from concentration of 0.05+ 0.5 to 0.8+8 , a reduction in growth from 4.5% to 100% was observed.
Conclusion: The results of this study showed that vancomycin and cefepime has synergic effect on Staphylococci
Fakhraldin Maroufi, Adel Salavati, Jalil Marabi, Faeze Foruzanfar,
Volume 11, Issue 4 (12-2017)
Abstract
Background and Aim: Work related musculoskeletal disorders shape a high percentage of physical and mental problems especially in health system work force. This study aimed to evaluate the effectiveness of ergonomic interventions by training the basics of ergonomics and exercise on neck pain in nurse staff of Tohid Hospital of Sanandaj.
Materials and Methods: This semi-experimental and interventional study was conducted on 60 nurses of Tohid Hospital of Sanandaj who had neck pain in the last quarter of 1394 and they were chosen by random sampling method and were divided into intervention and control groups. Data were gathered using standard Modified Qswestry Neck Pain Questionnaire and pain Numeric Rating Scale. After providing ergonomics trainings and exercises to intervention group, re-evaluation was carried out and the results were compaired to the control group. Data was analyzed using Mini tab 16 software, descriptive and analytic statistics, paired t-test, the correlation coefficient and linear regression.
Results: The average age in intervention and control groups was 35 and 33 years, and the average work experience was 13 and 12.9 years respectively. There was a statistical significant relation between three variables of age, work experience and marital status with the pain intensity variable (p-value<0.05), but gender had no effect on the pain intensity (p-value=0.128).
Conclusion: Standardization of the work methods and implementing exercises, can reduce neck pain and increase physical ability of work staff, which can reduce their work absenteeism and increase their motivation.
Parisa Moradimajd, Shahnam Sedighmaroufi, Shaqayeq Taghizadeh, Mr Jamileh Abolghasemi, Alireza Babajani,
Volume 18, Issue 1 (3-2024)
Abstract
Background and Aim: One of the basic principles in the safety of drug therapy for patients is the correct registration and labeling of anesthetic drugs, which can lead to the reduction of drug errors, the increase of drug and patient safety, the reduction of drug consumption and the environment, and the optimization of hospital costs.
Materials and Methods: This descriptive-analytical and cross-sectional research was conducted in February 2022 in the operating rooms of Iran University of Medical Sciences hospitals. The participants included 177 Anesthesia experts working in the hospitals’ operating rooms, who were included in the study by census method. The data was collected using the checklist for evaluating anesthetic drug registration and labeling guidelines and analyzed using SPSS software and one-way ANOVA, Fisher, and Pearson correlation coefficient statistical tests. The significance level was considered P value < 0.05.
Results: The average compliance with the guidelines for registration and labeling of anesthetic drugs in all hospitals was 3.559 out of the total score of 16. The average adherence to guidelines in 8 hospitals was significantly different from each other (P < 0.001). Hazrat Ali Asghar Hospital had the highest compliance rate, averaging 10.333 out of 16. Firouzgar and Shahid Akbarabadi hospitals were in the next rank, averaging 10.11 and 6.65, respectively. There was a negative and significant correlation between the level of compliance with the guidelines and the average work experience and age of the experts (P=0/17); However, gender did not significantly correlate with the degree of adherence to the guidelines(P=0/596).
Conclusion: According to the obtained results, compliance with the guidelines for registration and labeling of anesthetic drugs in most hospitals was assessed as weak and at an unfavorable level. Considering the importance of this issue in reducing medication errors and increasing patient safety, it is necessary to use empowerment and retraining courses for Anesthesia experts according to the latest guidelines.
