Search published articles


Showing 2 results for Meshkani
Medical Laboratory Director Competencies: State of the Basic Medical Sciences and Global Perspective
Mohammad Erfan Zare, Reza Meshkani, Mojtaba Abbasi, Farhad Shaveisi Zadeh, Atefeh Nasir Kansestani ,
Volume 11, Issue 3 (Supplement 1 2017)
Abstract
Background and Aim: There has been a long-lasting debate among medical laboratory-associated specialists about required competencies and educational background to qualify for directing medical laboratories in Iran. The aim of this study was to provide a comprehensive review regarding required training and competencies for becoming a medical laboratory director in Iran and all around the world.
Materials and Methods: A thorough search of the literature was carried out in scientific databases including Web of Science, Science Direct, Springer Link, Wiley Online, PubMed, Scopus, SID and web-based search engines such as Google and Google Scholar.
Results: The results revealed detailed required competencies for directing medical laboratories in the United States of America, Canada, European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) and its many affiliated European countries.
Conclusion: Our results indicate that in all assessed countries, specialists of basic medical sciences and also physicians, after passing certifying examinations, are equally qualified to direct medical laboratories. Indeed, Iran is the only country within the evaluated ones, in which basic medical sciences specialists (which have their own specific curriculum and are educated as clinical majors) have been eliminated from directing medical laboratory and the position has almost exclusively been available for graduates of pathology and it is important to revise this approach.

FAS and ACC dysfunction in visceral Adipose Tissue
Ehsan Khalili, Naghmeh Janat Alipour, Reza Meshkani, Karamolah Tolabi, Solaleh Emamgholipour,
Volume 14, Issue 2 (Jun & Jul 2020)
Abstract
Background and Aim: A great interest for determining the particular mechanisms underlying lipogenesis and adipogenesis has been raised among researchers in order to fight obesity. We aimed to investigate the gene expression of FAS and its role in regulation of lipogenesis and adipogenesis in visceral adipose tissues from obese and normal-weight subjects.
materials and Methods: A total of.participants including 40 obese patients(BMI≥35 kg/m2 according to WHO criteria) and 20 healthy subjects(BMI=18.8-24.9 kg/m2 according to WHO criteria) were recruited from who were referred to Erfan, Loghman Hakim, Sina, and Imam Khomeini hospitals bypass or sleeve gastrectomy surgeries in obese ones and elective surgery in controls. Participants were all woman aged from 20-50 years and postmenopausal subjects were not included in this study. Isolated total RNA from adipose tissue was used to synthesize complementary DNA(cDNA) and quantitative real-time PCR was performed for analyzing the gene expression of FAS, and ACC. Data was normalized to geometric means of GAPDH and β-actin expression levels.
Results: in VAT from obese subjects, gene expression of FAS was higher than in those from controls. We found a positive correlation between genes expression of FAS and ACC with obesity indices.
Conclusion: It appears that obesity is associated with dysregulation of FAS genes involved in lipogenesis and adpogenesis.

Page 1 from 1     

© 2025 , Tehran University of Medical Sciences, CC BY-NC 4.0

Designed & Developed by: Yektaweb