M Rahimkhani, Ma Mohagheghi,
Volume 1, Issue 2 (20 2008)
Abstract
Background and Aim: The human bowel contains a large and dynamic bacterial population (more than 500 species of bacteria). Some intestinal bacteria such as Streptococcus bovis , Enterococcus and Bacteroides fragilis have previously been suggested to be implicated in the promotion of colon carcinogenesis probably through the conversion of mutagen metabolites.
Materials and Methods: Thirty patients with colorectal cancer confirmed by colonoscopy examination and pathological survey were evaluated. Thirty healthy people who matched by sex and age with patient group were identified. Fecal samples were collected from patient and control groups were cultured in specific and non-specific culture media (aerobic and nonaerobic situations).Organisms isolated by microbial and biochemical pathways.
Results: S. bovis was predominant fecal microbial flora in nine (39.1%) patients and six (26.1%) of control group (P=0.657). Entrococcus was predominant fecal microbial flora in 6 (26.1%) patients and 2 (8.7%) of control group (P=0.657). B. fragillis was predominant fecal microbial flora in 8 (21.7%) patients and 2 (5.4%) of control group (P= 0.062).
Conclusion: Our results by fisher statistical analysis show that the incidences of fecal S. bovis, Enterococcus and B. fragilis in colorectal cancer were not significantly higher than health people.
Mohammad Reza Alibeik, Zeinab Bagheri, Niloofar Mohaghegh, Hamid Haghani,
Volume 9, Issue 2 (7-2015)
Abstract
Background and Aim: Materials and methods, as one of the most important
parts of a paper, introduces its scientific value. This study aims to investigate the
methodological quality of publications of Tehran University of Medical Sciences
(TUMS) indexed in PubMed.
Materials and Methods: In this descriptive, cross-sectional study, 400
articles affiliated to Tehran University of Medical Sciences and indexed in
PubMed until the end of 2012 were investigated. The type, purpose and subject
matter of all these articles were recorded in a checklist.
Results: The most frequently published reports were cross-sectional studies
(41.3%), followed by case-control studies (14.5%), case reports (14.3%), clinical
trials (13%), narrative reviews (4.8%), animal studies (3.3%), quantitative studies
(2.8%), quasi-experimental studies (2%), cohort studies (1.8%), case series (1%),
meta-analysis (1%), and systematic reviews (0.5%). When the articles were
classified according to National Library of Medicine (NLM) classification, most
papers were about musculoskeletal system (8.5%). Over half of the articles were
therapeutic (52.8%), followed by diagnostic (24.8%), prevention (12.3%),
prognostic (7.8%), and etiologic (2.5%). School of Medicine, Hazrate Rasoule
Akram hospital, and Endocrinology & Metabolism Research Institutes had the
highest number of articles among TUMS faculties, hospitals, and research centers.
Conclusion: Primary studies were the most common types observed in the
articles affiliated to Tehran University of Medical Sciences. Systematic reviews
and meta-analyses form only a small proportion of articles in the current research.
It seems that there should be a revision in the researchers' priorities to publish
papers with prevention purposes
Fatemeh Mohabati, Maryam Tajvar, Bahram Mohaghegh, Seyedpouria Hedayati, Mohammad Arab,
Volume 16, Issue 4 (Oct 2022)
Abstract
Background and Aim: Reforming the structure of medical universities and its continuous adaptation to the mission of the organization and new functions is an undeniable necessity. The purpose of this article was to explain how to implement this policy.
Materials and Methods: The current qualitative study was conducted in 2020 retrospectively based on Kingdon’s multiple streams model. Data collection was done using two methods: individual interviews and document review. Sampling of the managers and experts of the administrative development and transformation centers of the Ministry of Health and 12 universities of Medical Sciences as well as vice-chancellors of the universities was done in a purposeful and snowball method until data saturation was reached by conducting 19 individual interviews. Data analysis were done with framework and content analysis methods, and using MAXQDA 2020 software.
Results: The low of structural problems included quantitative and qualitative changes in new tasks in the environmental units of universities, interference and parallel work in the tasks of university units, and bargainings for restructuring by universities. The policy low included the obligation to make structural changes in the upstream laws and documents, including the Fifth Development Plan, and the cooperation of all stakeholders. The political process included the implementation of the Health Transformation and the Family Physician Plan, and the support of relevant policymakers and the approval of the law of becoming a university trustee in the law of the fifth plan of economic development and also gaining the all-round support of the stakeholders.
Conclusion: The medical sciences universities, as the headquarters arm of the Ministry of Health at the provincial level, need to have flexible structure in line with the needs of their surrounding units. In luential context factors in policy-making the reform of the structure of the headquarters of universities/colleges, in addition to the stream of structural problems, the main of which was the change in the duties of the units, along with the political determination created in the Ministry of Health, led to the simultaneous occurrence of three streams of problems, Politics and politics and finally opening the window of opportunity and changing the structure and organization of the headquarters of medical sciences universities.
