Showing 5 results for Noori
Taha Samad Soltani , Mostafa Langarizadeh, Maryam Zolnoori,
Volume 9, Issue 3 (9-2015)
Abstract
Background and Aim: Data mining is a very important branch in deeper
understanding of medical data, which attempts to solve problems in the diagnosis
and treatment of diseases. One of the most important data mining applications is to
examine the existing data patterns. The present study aims to examine the existing
data patterns of patients with asthma.
Materials and Methods: This study was performed on 258 patients with
respiratory symptoms, who referred to Imam Khomeini and Masih Daneshvari
Hospitals in 2009. All records were entered into Excel software, and data mining
add-ins were used. Analyses such as key influencers, cluster analysis of patients,
and detecting exceptions have been done.
Results: The most common clinical sign of asthma among subjects was severe
coughing, which was highly affected by thrills. The data were aggregated into 5
clusters for more general analyses. Their common denominator was then identified
and the records with exceptional features were determined. Then, following cost
analysis and setting the threshold value at 612, a questionnaire was developed
based on data features for diagnosis of asthma.
Conclusion: The developed framework for data mining and analysis is an
appropriate tool for knowledge extraction based on the data and their relationships.
Meanwhile, it can identify and fill the existing gap in medical decision- making
when using clinical guideline
Maryam Ahmadi, Tayebeh Noori, Kambiz Bahaadin Beigy , Esmaeil Mehraeen,
Volume 10, Issue 1 (4-2016)
Abstract
Background and Aim: For more than forty years, telemental health services have been used as a successful mean in various fields such as treatment and preventive interventions. This study was aimed to determine the viewpoints of health information management (HIM), and mental health professionals about telemental health services for veterans with mental disorders.
Materials and Methods: This cross-sectional survey was conducted in 2013. The study population consisted of two groups: the first group included mental health professionals working in psychiatric hospitals in Tehran and the second group comprised HIM professionals. The data were collected using a questionnaire that its validity was confirmed by experts and the reliability was estimated through test-retest method. The data analysis was performed using SPSS 17.0 and descriptive statistics.
Results: The findings showed that from the mental health experts' viewpoints, highest impact of the use of telemental health services related to medical travel costs with average 4.37 and the lowest impact replacement with the face to face treatment with average 2.68.
Conclusion: In general, the groups participating in this study stated that in situations where access to care was difficult, telemental health services could be used as a reliable alternative for the war disabled care needs. Therefore, it is suggested that Iranian foundation of Martyrs and Veterans Affairs and the health system administrators take more serious measures for the implementation of telemedicine for veterans.
Maryam Goodarzi, Seyed Soroush Ghazinoori, Reza Radfar, Abbas Kebriaeezadeh,
Volume 13, Issue 5 (Dec & Jan 2020)
Abstract
Background and Aim: Given the increasing variety of biological drugs in the world and the significant role of these drugs in patients' quality of life, as well as the high risk of drug productions, biopharmaceutical companies need to revise their business model. The purpose of this study is to review the dimensions and components of biopharmaceutical companies.
Materials and Methods: This is a comprehensive review and is based on the existing studies by searching valid databases such as PubMed, Science Direct, SID, Iran doc and Google Scholar from 2000 to 2019. All the searches were performed based on keywords such as “Components of Business Model”, and “Business Model of Biopharmaceutical Companies”. The initial search yielded 820 articles. After screening, 23 articles were selected for final study.
Results: The overall dimensions of business model in biopharmaceutical companies are identical to other companies, but the components of the business model of these kinds of companies are various based on their performance, and the most important components include the value proposition, key resources, success factors, revenue stream and cost structure.
Conclusion: Introducing the components of business model in this study can be adjusted based on the dimensions of business model and the characteristics of each biopharmaceutical company.
Mobina Noori, Leila Fozouni, Ania Ahani Azari,
Volume 16, Issue 3 (Aug 2022)
Abstract
Background and Aim: Wastewater is one of the most dangerous and important sources of pathogens and their treatment does not always guarantee the elimination of pathogenic bacteria. Enterococci, as opportunistic pathogenic bacteria, fastidious and cause of nosocomial infections, have a wide environmental distribution and one of the routes of their transmission to humans is water and wastewater. The increasing rate of drug- resistance among bacteria indicates the need for investigation of novel antibacterial agents or their combination effects. The aim of this study was to investigate the effect of linezolid in combination with rifampin on the elimination of multidrug- resistant enterococci in two treatment plants in Golestan province.
Materials and Methods: Enterococcus species from eighty samples were isolated from treatment plants in two cities of the Golestan Province (North of Iran) including Gorgan and Bandar-e Torkaman during January-June 2021. The isolates were identified based on the most probable number (MPN), filtration, microbiological tests and finally by using specific gene detection by ddlE primer with polymerase chain reaction. Kirby Bauer performed an antibiotic resistance pattern according to CLSI- 2020 guidelines for six classes of antibiotics. The minimum inhibitory concentration of linezolid was determined individually and by synergist effect with rifampin by broth microdilution method.
Results: After phenotypic and molecular diagnosis (PCR) of raw and treated wastewater samples, in 32 (40%) wastewater samples, enterococci species were identified and confirmed. Tetracycline was the least effective so, about 100% of Enterococcus faecalis and Enterococcus faecium isolates were resistant to it. The prevalence of linezolid-resistant E. faecalis was 11%. A total of 20 enterococcal isolates (62.5%) had multiple resistance. The concentration of linezolid in combination with rifampin, which inhibited 90% growth of the isolates (MIC90) was 1μg /ml, four-fold lower than linezolid alone (MIC90=4 μg/ml). In addition, none of the enterococci isolates showed resistance to the linezolid/rifampin combination (P=0.001).
Conclusion: The results of this research confirmed the presence of enterococci resistant to vancomycin and other antibiotics in the wastewater treatment plant samples in Golestan province. The favorable combination effect of linezolid and rifampin on the inhibition of multi-drug resistant isolates implies their synergy.
Ali Maleki, Marivan Noori, Rezvan Zomorodi, Fakhredin Saba,
Volume 16, Issue 5 (Dec 2022)
Abstract
Background and Ami: Identifying the genotype of blood groups in different communities will give the decision makers of the health system to take the necessary measures to prevent and identify the possible side effects of blood transfusion, including the production of alloantibodies. Duffy blood group has increased the possibility of alloantibody production in beta-thalassemia major patients who regularly need blood transfusion due to different types of genotype with different prevalence. However, no study has been conducted regarding the frequency of Duffy blood group distribution in beta-thalassemia Kurd patients dependent on blood transfusion.
Materials and Methods: This case-control study was conducted on 100 patients with beta thalassemia major, as case group and 50 healthy individuals, as control group, in Bostan Clinic, Kermanshah University of Medical Sciences. After collecting peripheral blood samples from people participating in the study, DNA was extracted from peripheral blood mononuclear cells. Then, using PCR-RFLP and electrophoresis, Duffy genotypes including FYA/A, FYB/B and FYA/B were identified.
Results: The results of Chi-square test showed that in the patient group, there is no statistically significant difference between the two genders in terms of the frequency of distribution of Duffy genotypes (P=0.588). On the other hand, in the healthy group too, there was no statistically significant difference between the two sexes in terms of the frequency of distribution of Duffy genotypes (P=0.707). According to nominal regression results, although the distribution ratio rate (95% confidence interval) of FYA/FYA and FYB/FYB genotypes as compared to FYA/FYB genotype (reference category) in the patient group as compared to healthy people was 2.42 (0.7 to 8.34) and 0.76 (0.36 to 1.64) respectively, but there was no statistically significant difference between the case and control groups in terms of the distribution frequency of these genotypes (P<0.05).
Conclusion: The frequency distribution of Duffy genotypes in beta-thalassemia major patients is similar to that of healthy people, and there is no relationship between the distribution of Duffy genotypes and beta-thalassemia disease. FYB genotype has the highest frequency in both case and control groups
