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Showing 2 results for Taghavi Gilani
The Comparison of Ketorolac, Paracetamol and Pethidine on Postoperative Pain Control for Outpatient Transurethral Lithotripsy
Mehryar Taghavi Gilani, Majid Razavi, Alireza Bameshki, Arash Peivandi Yazdi,
Volume 16, Issue 6 (Feb 2023)
Abstract
Background and Aim: Treatment of acute postoperative pain is one of the most important measures to improve recovery. Different methods of local and regional anesthesia, and also numerous intravenous drugs have been used.  In this study, the analgesic effect ketorolac, paracetamol and pethidine in the postoperative pain control of outpatient transurethral lithotripsy was evaluated.
Materials and Methods: This clinical trial was performed on 96 patients who were candidates for outpatient transurethral lithotripsy in Mashhad Imam Reza Hospital. In randomized double blinded study, at the end of the operation, 30 mg of intravenous ketorolac to the first group, 1 gram paracetamol in half an hour to the second group and 50 mg of pethidine to the third group were injected. Pain was assessed every 10 minutes to half an hour and then, every half an hour to 4 hours by numerical rating scale (NRS). Finally, the data were analyzed by SPSS v16 software. The relationship between quantitative variables was analyzed by analysis of variance and the qualitative variables was assessed by Chi-square test and P<0.05 was considered significant.
Results: There was no significant difference between three groups in demographic information. The pain intensity in the first 10 minutes after surgery was the same between the groups (P=0.372), but the pain intensity at 20, 30 and 60 minutes after surgery was significantly different in the three groups (P.values ​​0.005, 006, and 0.001 respectively), and was lower in the pethidine group. In other hours after surgery, no significant difference in pain control was observed between the three groups. The need for additional analgesia was higher in the paracetamol group than in the other two groups (P=0.025) in the first hour. Hemodynamic changes and surgical complications such as nausea and vomiting were the same in both groups.
Conclusion: The present study showed that pethidine causes better pain relief than ketorolac and paracetamol in the first hour after surgery, but after 60 minutes there is no significant difference between these three groups.
 

The Evaluation of Relationship of Preoperative Hypertension with Intraoperative Hemodynamic Changes and Early Post-Operative Cardiovascular and Cerebral Complications in Cataract Surgery
Mahdieh Jafari, Majid Razavi, Sepideh Fanaei Nookar, Mehryar Taghavi Gilani,
Volume 19, Issue 1 (4-2025)
Abstract
Background and Aim: Hypertension is one of the most common comorbidities in cataract surgery and severe hypertension sometimes cause surgery to be postponed. The purpose of this study is to evaluate the relationship between preoperative hypertension and intraoperative hemodynamic changes and postoperative early cardiovascular and cerebral complications on cataract surgery.
Materials and Methods: This study was performed on 160 patients with cataract surgery in Mashhad Khatam-al-anbia hospital. Before induction, the patients were divided into three groups by blood pressure measurement: normotensive (blood pressure <140/90) 100 patients, hypertensive (blood pressure 140/90 to 180/110) 30 patients and hypertensive crisis (blood pressure>180/110) 30 patients. Blood pressure and heart rate were assessed before entering to operating room, before induction and every 5 minutes to the end of surgery, after recovery and ward transfer. Cardiovascular and neurological complications were assessed 24 hours after surgery. Data were analyzed by SPSS software. P<0.05 was considered significant.
Results: There was no significant difference between patients for demographic and preoperative hemodynamic parameters. Preinduction, the blood pressure increased compared to the ward, which was more significant in the hypertensive and hypertensive crisis groups (P=0.001). After induction, systolic blood pressure reduced which was more significant in the hypertensive crisis group than two other groups (P=0.001). The heart rate increased after transferring to the operation room and returned to normal after induction of anesthesia, but in three groups were not statistically significant (P=0.25). Systolic blood pressure < 90 mmHg during the surgery, and also cardiovascular and nervous complications up to 24 hours were not significantly different in three groups (P=0.75 and P=0.08, respectively). 
Conclusion: Blood pressure instability was more common in patients with hypertension crisis, but no early or debilitating complications were observed. Primary hemodynamic changes were rapidly reduced and controlled by induction of anesthesia. According to the findings, preinduction blood pressure alone is not sufficient to cancellation of cataract surgery.

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