Showing 13 results for Tol
H Choobineh , Sh Alizadeh , Mk Sharifi Yazdi , F Vaezzadeh , H Dargahi , Ak Pourfatolah ,
Volume 1, Issue 1 (9 2007)
Abstract
Background: With due attention to the prevalence of thalassemia in Iran and patients' importunate needs for blood intake, this study aimed to inspect contaminations due to repeated blood transfusion which does not sift in blood donation. One such contamination is cytomegalovirus infection, which is an important pathogen in immunosuppressive patients or receivers of transplanted organs.
Methods: This cross sectional study was conducted on 311 thalassemia patients under age of 15 yr who was receiving blood from Hospitals in Tehran and Noorabad Mamasani repeatedly. To determine active infection (presence of IgM antibodies) of cytomegalovirus, ELISA method was used. In addition, 225 healthy people under age of 15 yr were studied as testified group and finally all data were analyzed using SPSS ver. 11.5.
Results: 12.9 % of patients were positive from the view point of active infection. Regional separation of patients showed that the patients resided in Tehran are more contaminated to this virus than patients of other cities.
Conclusion: The range of cytomegalovirus active infection in thalassemia patients is high. One reason might be the infected blood intake or immunosuppressant (weakness of immune system) in patients, therefore immunity care of these patients and negative serologic blood intake with respect to and also hematic parents (parents with the same blood) are important.
Sima Esmaeili Shahmirzadi, Davoud Shojaeizadeh, Kamal Azam, Leili Salehi, Azar Tol, Monavvar Moradian Sorkhkolaei,
Volume 6, Issue 3 (7 2012)
Abstract
Background and Aim: Increase in life expectancy is associated with non-communicable diseases. This study is aimed to survey the effect of chronic diseases on the quality of life among the elderly people in elderly care centers in the East of Tehran in 2011.
Materials and Methods: This is an analytical study in which 424 people were randomly selected. They were members of elderly care centers and were 60 years of age or higher. The data collection instruments were a standard quality-of-life questionnaire(SF36) and a chronic diseases record checklist. The data were collected in an interview. For data analysis purposes, Independent T-Test, ANOVA, and Pearson correlation coefficient were used.
Results: The mean age of participants was 67.34±7.16. Some 92.2% of patients were suffering from at least one chronic disease, and there was a significant statistical difference between the mean points of all aspects of quality of life of those suffering from chronic diseases and those without a history of chronic diseases(P<0.001). Moreover, there was a significant relationship between the quality of life on the one hand and gender, marital status, economic status, and education on the other(P<0.05).
Conclusion: The findings show that an increase in the number of chronic diseases leads to a decrease in the quality of life, and that the application of appropriate educational and interventional approaches can help take effective steps to enhance the old people's health.
Azar Tol, Sima Esmaeili Shahmirzadi, Davoud Shojaeizadeh, Mohamad Reza Eshraghian, Bahram Mohebbi,
Volume 6, Issue 3 (7 2012)
Abstract
Background and Aim: Cardiovascular diseases are the main cause of death and disabilities in the world. The purpose of the present study is to determine the perceived barriers and benefits of adopting health-promoting behaviors among individuals at risk of cardiovascular diseases referring to TUMS Teaching Hospitals in 2011.
Materials and Methods: This is a cross-sectional study in which 325 patients at risk of cardiovascular diseases were randomly selected. The data were collected using a self-made questionnaire having three parts: 14 items for demographic and health-related variables, 12 items for perceived barriers, and another 12 items for benefits. For data analysis, SPSS 18 was used.
Results: The mean age of patients was 53.56±11.27 about 47.7% of patients(n=155) were female and 52.3% (n=170) were male. There was a meaningful relationship between the mean of perceived benefits on the one hand and occupation, physical activity, type and frequency of physical activity, smoking and awareness of cardiovascular diseases on the other(p0.001). Moreover, the mean of perceived barriers showed a meaningful relationship with occupation, smoking and awareness of cardiovascular diseases(p0.05).
Conclusion: The findings of the present study revealed that demographic and health-related variables could affect the perception of barriers and benefits of adopting certain behaviors for the prevention of cardiovascular diseases. Therefore, using interventional and educational approaches appropriate for target group features can help us take effective steps towards health promotion.
Hasan Abolghasem Gorji , Heshmatollah Asadi, Masoud Roudbari , Ahmad Barati Marnani , Mojtaba Hasoumi , Mohammad Mohseni ,
Volume 8, Issue 3 (9-2014)
Abstract
Background
and Aim: Readiness
to face changes
and transformation in health fields is one of the main factors in
health organizations’ success. The main purpose of the present study was to
determine the relation between culture and readiness to accept transformation in
single-specialty hospitals.
Materials
and Methods: Readiness
to face changes
and transformation in health fields is one of the main factors in
health organizations’ success. The main purpose of the present study was to
determine the relation between culture and readiness to accept transformation in
single-specialty hospitals.
Results:
Studied hospitals had low power distance, high uncertainty avoidance,
feminist, collectivist and short-term orientation. There
was a significant relation between readiness to accept transformation with
factors such as: Power distance (P<0/05, r=-0/236), uncertainty avoidance
(P<0/05, r=0/143) and being feminist (P<0/05,
r=-0/239).
There was no significant relation between readiness to accept transformation
with factors such as collectivist and short-term orientation
(P>0/05).
Conclusion: Low
power distance, high uncertainty avoidance and being feminist are effective factors in
accepting transformation among studied hospitals’ staffs. These staffs are
culturally prepared to accept evolution plans.
Ali Arab Kheradmand , Enayatollah Shabani, Tannaz Azadi,
Volume 9, Issue 1 (5-2015)
Abstract
Background and Aim: Today universities admit International Students as well as national students. Tehran University of Medical Sciences has been also started admitting International Students in regards of its Internationalization aims. Student’s satisfaction is of high importance in order to gain the given goals. The purpose of this study was to evaluate the satisfaction of International students of TUMS.
Materials and Methods: This was a descriptive study. The target group was international students of TUMS, the participants were selected through availability sampling. The research instrument was researcher-made questionnaire which the reliability calculated as 0.97 by Chronbach’s alpha. The data was analysied by Microsoft Excell version 2010.
Results: The overall satisfaction of the students was 70% (satisfied and completely satisfied) while the overall dissatisfaction was 10% (dissatisfied and completely dissatisfied).
Conclusion: Given satisfaction of more than half of the International students, TUMS has performed reasonably. Based on the results obtained in this research the university may pay attention to the fields reported as dissatisfied.
Celin Telefian, Enayatolah Kalantar, Mohammad Mehdi Soltan Dallal,
Volume 9, Issue 3 (9-2015)
Abstract
Background and Aim: Cystic fibrosis is a common hereditary and autosomal
disorder. One of the factors in cystic fibrosis is Burkholderia cepacia which can be
transmitted through the sharing of admitted patients with hospitalized patients.
Purpose of this study, was isolation and identification of Burkholderia cepacia from
respiratory secretions from Masih Daneshvari Hospital cystic fibrosis patient.
Materials and Methods: In this study, during 8 months from 2011 till
2012, 100 cases of pulmonary secretions were collected in Masih Daneshvari
hospital patients. The specimens were cultured on both MacConkey agar and
Burkholderia cepacia selective agar (BCSA) medium. After an incubation of 48
hours at 35°C, suspected colonies were isolated and by using of phenotypic and
biochemical tests like TSI agar, simmons citrate medium, indol and motility, MRVP,
oxidation - fermentation (OF), arginine- ornithine - lysine decarboxylase test,
Dnase test, and polymyxin resistance were identified.
Results: Using BCSA medium and biochemical tests led to isolation and
identification of five Burkholderia cepacia strains from 100 respiratory samples.
However, using Mac Conkey no Burkholderia cepacia was detected.
Conclusion: Our results clearly indicate the use of BCSA medium as a specific
medium for isolation of Burkholderia cepacia in cystic fibrosis patients. So,
presence of 5% Burkholderia cepacia in cystic fibrosis infections suggests
detecting this bacterium, in a specific and sensitive culture medium.
Mina Sadat Hashemiparast, Roya Sadeghi, Mohammadreza Ghaneapur , Kamal Azam , Azar Tol ,
Volume 10, Issue 3 (7-2016)
Abstract
Background and Aim: Effective educational programs, is one of the most basic methods in prevention of Nosocomial infection. This study aimed to compare the effects of E-learning versus lecture-based education in prevention of Nosocomial infections among hospital staffs.
Materials and Methods: A randomized pre and posttest control group design was conducted on 98 hospital staffs in 2013 after allocating into two groups of "lecture-based education" and "E-learning”. Data were collected by a researcher-made questionnaire which its validity and reliability was confirmed by a pilot study. Wilcoxon, Paired and Independent sample T-test was conducted using SPSS, version18.
Results: There was a significant difference for outcomes before and after education based on two approach of lecture-based (p=0.01) and E-learning (p=0.01).The mean and standard deviation of knowledge in lecture-based education and E-learning group were 12.73± 2.76, 11.50 ± 2.64 respectively. The level of knowledge in the lecture group was significantly higher than that of participants in the E-learning group (p=0.02).
Conclusion: Despite the effectiveness of E-learning in learning and raising awareness of the learners, using of this method among health-related organizations need to empower employees, remove the barriers and suitable infrastructure.
Hossein Dargahi, Shiva Toloui Rakhshan , Jamil Sadeghifar,
Volume 10, Issue 3 (7-2016)
Abstract
Background & Aim: One of the most important and useful models for assessing hospital performance is the Pabon Lasso Model, a graphical model that determines the relative performance of hospitals using three indicators: 1. Bed Occupancy Rate (BOR); 2. Bed turnover (BTO); 3 Average Length of Stay (ALS). The aim of this research is to investigate the performance of the hospitals affiliated with Tehran University of Medical Sciences in Iran during the year 2011 based on the Pabon Lasso Model.
Materials & Methods: This descriptive and cross-sectional study conducted in 2011. All the 16 hospitals affiliated to Tehran University of Medical Sciences formed the study population. Data was analyzed by Excel software and Pabon lasso model.
Results: The following average results for each performance indicator were obtained: Average Length of Stay (ALS) = 6.55 days. Bed Occupancy Rate (BOR) = 74.151% and Bed Turnover (BTO) = 70.24 times per year18.75% hospitals were located in the Pabon Lasso Model zone 1.25% hospitals in zone 2.25% of hospitals in zone 3, and 31.25% hospitals in zone 4 of the model.
Conclusion: The study showed that 75% of the studied hospitals were inefficient. Applying Pabon Lasso model compared hospital's performance. Thus, using one of the active ways of problem recognition in hospitals and perceiving the relation of performance indicators will be helpful in establishing new policy and reviewing current policy in order to maximize performance capacity.
Rahmatollah Marzooghi, Heidari Elham,
Volume 11, Issue 2 (7-2017)
Abstract
Background and Aim: To fulfill its mission, the health system needs reform in various sectors including supervisory areas. That is because the quality of supervision can have various consequences such as increase or decrease of innovative self-efficacy through various factors. Therefore, the aim of this study was to explain the mediator role of perception of organizational justice in the relationship between abusive supervision and innovative self-efficacy.
Materials and Methods: This is a correlational descriptive-analytical study. The sample included 225 employees of Shiraz University of Medical Sciences, who were selected through random sampling. The research instruments were questionnaires of abusive supervision, innovative self-efficacy and perception of organizational justice, which were distributed among the sample after calculating their reliability and validity.
Results: The results showed that abusive supervision had a significant negative impact on the perception of organizational justice and employee’s innovative self-efficacy. Also, the perception of distributive justice has a significant positive impact on innovative self-efficacy and a mediation role in the relationship between abusive supervision and innovative self-efficacy.
Conclusion: In order to enjoy innovation, health-oriented organizations should reduce abusive supervision in managers’ and supervisors’ behavior; therefore, with the increase of employees’ feeling of innovative self-efficacy, they can lead to the realization of the mission of these organizations.
Hojatollah Soleimani, Fatemeh Nooshinfard, Fahimeh Babolhavaeji,
Volume 12, Issue 1 (5-2018)
Abstract
Background and Aim: To understand veterans’ needs and to make future generations familiar with the culture of self-sacrifice and martyrdom, we need a database to store information. The first step for designing a base is to provide a conceptual framework of the base. This study aims to provide a conceptual model to create the national base of veterans in Iran.
Materials and Methods: This research was conducted in a two-step, mixed approach. The first step was conducted using content analysis method (quantitative) and the second step using Delphi (qualitative) technique. Data collection tool was Excel 2016 software. With the help of Delphi technique, a researcher-made conceptual pattern was sent to the experts in three rounds. Based on their views, the final plan of national base of veterans was formed.
Results: Among the main components, introduction to the war was removed, history of war changed to history of wars, link to links, other materials to other contents, art and war to war and art, and the sub-component of possibilities turned into the main component. Veterans’ personal information turned into veterans’ database that changed into subsidiary components of the martyrs / veterans / prisoners-of-war / warriors database.
Conclusion: The main components of the conceptual pattern of national base of veterans of Iran include: home page, introduction, conflicts and operations, equipment, war zones, facilities, news, cemeteries of martyrs, veterans’ rules, questions and answers, history of wars, war and art, veterans’ database, archives, links, guide, contact with us, FAQs, other content, resources, about the base, search, map.
Ehsan Khalili, Naghmeh Janat Alipour, Reza Meshkani, Karamolah Tolabi, Solaleh Emamgholipour,
Volume 14, Issue 2 (Jun & Jul 2020)
Abstract
Background and Aim: A great interest for determining the particular mechanisms underlying lipogenesis and adipogenesis has been raised among researchers in order to fight obesity. We aimed to investigate the gene expression of FAS and its role in regulation of lipogenesis and adipogenesis in visceral adipose tissues from obese and normal-weight subjects.
materials and Methods: A total of.participants including 40 obese patients(BMI≥35 kg/m2 according to WHO criteria) and 20 healthy subjects(BMI=18.8-24.9 kg/m2 according to WHO criteria) were recruited from who were referred to Erfan, Loghman Hakim, Sina, and Imam Khomeini hospitals bypass or sleeve gastrectomy surgeries in obese ones and elective surgery in controls. Participants were all woman aged from 20-50 years and postmenopausal subjects were not included in this study. Isolated total RNA from adipose tissue was used to synthesize complementary DNA(cDNA) and quantitative real-time PCR was performed for analyzing the gene expression of FAS, and ACC. Data was normalized to geometric means of GAPDH and β-actin expression levels.
Results: in VAT from obese subjects, gene expression of FAS was higher than in those from controls. We found a positive correlation between genes expression of FAS and ACC with obesity indices.
Conclusion: It appears that obesity is associated with dysregulation of FAS genes involved in lipogenesis and adpogenesis.
Asma Maleki, Zahra Kashani Khatib, Shaban Alizadeh, Amir Ali Hamidieh, Ali Akbar Pourfatollah,
Volume 15, Issue 2 (Jun & Jul 2021)
Abstract
Background and Aim: Blood malignancies, one of the most common cancers in the world, cause a large number of deaths each year. Many inherited and acquired factors are involved in the development of this disease. Exosomes are a very small model of cells that are secreted by most cells in the body under physiological and pathological conditions. On the other hand, they have found a special place in the treatment of these diseases because of their very small structure and biodegradability.
Materials and Methods: This study is a systematic review article. For this study, the electronic databases such as PubMed, Scopus and Web of Science were reviewed and 110 original and review articles were studied from 2000 to 2020. Exosome, blood malignancies and immunotherapy were used as keywords along with a number of other related terms such as tumor microenvironment, acute myeloid leukemia, acute lymphoid leukemia, chronic lymphoid leukemia and multiple myeloma (Exosome AND Leukemia, Leukemia AND Immunotherapy, Exosome AND Cancer, AML AND Exosome) to search in these databases. Finally, 51 sources that related to exosomes and myeloid and lymphoid blood malignancies were used.
Results: The genomic profile of malignant cells and tumor microenvironment changes in the conditions of the disease. The contents of exosomes released by leukemic cells, including anti-apoptotic proteins, various microRNAs, angiogenic agents, heat shock proteins and oncogenes involved in the development of inflammatory phenotype in the target cells, are known as factors involved in the pathogenesis of leukemia. A variety of therapeutic materials such as anti-inflammatory drugs, recombinant proteins, siRNA and the inhibitor of various microRNAs can also be packaged in the exosomes with several ways and used to treat leukemia.
Conclusion: Exosomes derived from malignant cells play the important role in the growth and proliferation, angiogenesis, metastasis, resistance to chemotherapeutic agent, and the escape of cancer cells from the immune system by the modification of tumor microenvironment. The role of exosomes in the creation and development of blood malignancies has been proven. Therefore, using of them will probably be very helpful and promising in the treatment of these disorders with various forms.
Mehdi Raadabadi, Zahra Tolideh, Zahra Shoara, Zahra Yeganeh, Jamil Sadeghifar, Khalil Momeni,
Volume 18, Issue 1 (3-2024)
Abstract
Background and Aim: There is limited evidence about the effect of the corona disease epidemic on the efficiency of hospitals in Iran. This study was conducted with the aim of investigating the effect of the Covid-19 epidemic on the productivity of public hospitals in Ilam province.
Materials and Methods: This retrospective descriptive research has investigated the performance of 9 hospitals in Ilam province during a four-year period(1397-1400) based on the Pabon Lasso graphic model. The desired data were extracted from the HIS system of the hospitals and the key performance indicators of BOR, BTR and ALOS were calculated. The Pabon Lasso diagram was drawn with Excel software.
Results: The results showed that the bed occupancy percentage in teaching hospitals is significantly higher than non-teaching hospitals (P<0.05). Based on the results, the percentage of bed occupancy and the rate of bed rotation after the covid 19 pandemic has decreased significantly (P<0.05). The average length of the stay of patients also increased after the pandemic (P<0.05). Overall evaluation of hospital efficiency based on the Pabén Lasso model shows that the frequency of hospitals located in Nakara district has decreased from 4 hospitals before the pandemic to 3 hospitals, although hospitals in Kara district have not changed during this period.
Conclusion: Most of the researched hospitals, especially non-teaching hospitals, have low bed occupancy. Weakness in the service delivery chain, especially diagnostic services and specialized and super-specialized services, is one of the main reasons for this situation. Moving towards a change in the way hospitals are managed and having more flexibility in the structure and implementation in the short term and prioritizing large hospitals with a complete chain of services can lead to a way out of the current inefficient situation.
