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Mehdi Basakha, Kazem Yavari , Hosein Sadeghi, Alireza Naseri ,
Volume 9, Issue 2 (7-2015)
Abstract

Background and Aim: The recently emerged symptoms of population aging have raised serious concerns in some developed countries. A recent report by the United Nations (UN) indicates that aging is more rapidly growing and is even more serious in developing countries than it is in certain other countries. Therefore, this study is aimed to determine the impression of aging on non-oil economic growth. Materials and Methods: A simple economic growth model was built which would take demographic variables into account. Then, using the country's data for the years 1967-2011, the researchers tried to estimate autoregressive distributed lags (ADL). The short- and long-term models, and error correction model were estimated using Microfit 4.0 software. Results: The findings show that physical capital, human capital and trade openness have a significant positive effect on per capita income, both in the long and in the short run. Similarly, the regression analysis indicates that “Ageing Index” may have a significant effect on economic growth in Iran’s non-oil sector. Conclusion: Due to the young makeup of Iran's population, the signs of aging economy have not raised sensitiveness but predictions indicate that the aging process in Iran will be intensified in the coming decades and its negative effects will emerge in near future. Therefore, due to the long-term effects of aging on economic growth, working structure and retiredness reform policies, it is vital to stabilize population growth at an optimal rate, and more importantly, pay attention to capital storage.
Ali Reza Yavar, Zahra Batooli, Fatemeh Sheikhshoaei, Sara Ahmadizadeh,
Volume 16, Issue 2 (Jun 2022)
Abstract

Background and Aim: The outbreak of the Covid-19 pandemic has led to the emergence of new information needs for people with diverse information literacy. Both infected and healthy people feel the need to have essential and practical information about this pandemic. One of the concerns of Covid-19 patients is their need for reliable and sufficient information about various aspects of the disease. Understanding the information needs of patients and the experiences of people who have been infected and recovered from the disease can be a suitable and reliable source of information. So the aim of this study was to identify the information needs of patients with Covid-19.
Materials and Methods: This research was employed a qualitative approach using conventional content analysis. Key informants were Covid-19 recovered patients in Kashan city who had a history of admission in medical centers. Sampling consisted 17 participants (11 males and 6 females) who were selected from almost different social classes through purposeful method. The data were collected using a semi-structured interview and the saturation point was reached at 17 interviews. Data were analyzed using the Diekelmann’s seven-stage method.
Results: The results of this study included 430 primary codes that after removing and merging duplicate codes, seven main themes and 30 categories were identified in the field of information needs were extracted. Main themes and categories included understanding the nature of the disease (the origin of the disease, knowledge about the symptoms, transmission and types of mutations), prevention (health protocols, prevention equipments, and vaccination), treatment (diagnostic tests, type of disease treatment, disease process, costs, psychological support), nutrition (the type of nutrition for prevention, during illness and after recovery), communication with others (type, length and conditions of quarantine, how to communicate with others), statistics, and information sources (up-to-date, valid, and types).
Conclusion: The most critical information needs of Covid-19 patients include information about the nature, treatment, and preventive measures of the disease. Social media and oral information such as doctors, friends, and acquaintances were also reported as the most important sources of information. Therefore, this study suggests that health managers provide the most up-to-date and reliable information and news related to Covid-19 through the most appropriate and accessible media.

Shima Derakhshan, Negar Yavari Tehrani Fard, Nahid Abotalbe, Maryam Naseroleslami,
Volume 17, Issue 2 (5-2023)
Abstract

Background and Aim: Today, natural compounds such as peptides and probiotics can be mentioned as a supplement to the treatment of diseases such as cancer. These compounds may be effective in preventing the progression or treatment of cancer by affecting some molecular pathways including inflammation. The aim of this study was to investigate the effect of D-peptide-B and B.bifidum probiotic lysate on the expression of TNF-α and IL-1 genes in gastric cancer cells of AGS cell line.
Materials and Methods: In this study, AGS and HEK cells were cultured in DMEM medium with 10% bovine serum. The cells were treated with different concentrations of D-peptide-B and B.bifidum lysate and were incubated for 24 hours. The cell viability was checked by MTT. For molecular investigations, after RNA extraction and cDNA synthesis, the relative expression of TNF-α and IL-1 genes was evaluated using Real time PCR, and the data were analyzed using statistical methods One-way ANOVA.
Results: The MTT results indicated that the AGS cancer cells’ survival rate decreased after treatment with dipeptide-B and lysate of B.bifidum as compared to HEK control cells. Furthermore, the study found that the expression levels of TNF-α and IL-1 genes in gastric cancer cells were significantly higher after treatment with D-Peptide-B, bacterial lysate, or both, when compared to normal HEK cells (P≤0.05). Specifically, the IL-1 gene expression increased by 300% (4 times) for peptide treatment, 100% (2 times) for bacterial treatment, and 650% (7.5 times) for combined treatment. Similarly, the TNF-α gene expression increased by 350% for peptide treatment, 100% for bacterial treatment, and 520% for combined treatment. These results suggest that these compounds may have induced cell death in cancer cells by affecting other molecular pathways.
Conclusion: Considering that D-peptide-B and B.bifidum lysate had no significant toxicity on normal cells and caused a significant decrease in the survival of cancer cells and this toxicity was dose dependent, therefore, consideration might be given to these natural compounds in treatment of gastric cancer.

Mahboubeh Fatemi, Mohammad Reza Yaghoobi-Ershadi, Yavar Rassi, Mohammad Mehdi Sedaghat, Hassan Vatandoost, Mahboubeh Bayat, Mehrdad Zarabi, Fatemeh Nikpoor, Amir Ahmad Akhavan,
Volume 18, Issue 5 (10-2024)
Abstract

Background and Aim: Training and proper distribution of human resources are essential for maintaining and promoting society’s health. The first step in any health-related planning is to assess the current situation to draw a clear picture of the future to balance demand and supply. This research was conducted to assess the current situation of medical entomology and vector control/biology and vector control of the diseases in the country and determine the required human resources till 2025.
Materials and Methods: In this study, a “modified and combination model” was used, including the Hall model, which is location-based, and the Australian health workforce estimation model, which is a needs-based approach. The research was carried out in multiple stages, which included collecting the required data (number of faculty members, students, and graduates), the number of private companies providing spraying, and pest control services in all cities of the country and finally holding meetings with the board members of Biology and vector control of diseases and experts to estimate the human resources required in this field.
Results: Based on the data collected and face-to-face interviews conducted during six sessions with the experts in this field, it has been estimated that a total of 985 graduates have been trained in this discipline to date, while there is a requirement for 1,338 graduates in this area. Consequently, it is essential to train an additional 353 individuals in this field by the year 1404. In light of the country’s sixth five-year development plan, which allocates 30 percent of the total student population to postgraduate studies, it is imperative to prepare 35 individuals at the doctoral level, 71 at the master’s level, and 247 at the undergraduate level.
Conclusion: It seems that by accepting an average of 9 people at the Ph.D. level, 18 people at the master’s level, and 62 people at the bachelor’s level, in addition to matching the amount of demand and supply, there will be no problem for the employment of the graduates of this field.


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