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Readiness Survey And Comparison Of Educational Hospitals Of Medical Sciences University Of Urmia To Deploy Electronic Medical Records
Mostafa Langarizadeh , Elahe Gozali , Farahnaz Sadoughi ,
Volume 7, Issue 4 (11-2013)
Abstract

Background and Aim: Development of information and communication technology has led to enormous changes in different areas. Electronic medical records system is valuable to access patient data in hospitals. This study aimed to investigate and compare the educational hospitals of Uemia University of Medical Sciences in case of technical, organizational and legal to establish the system.

Materials and Methods: The study was a descriptive cross-sectional study. The study population consisted of 98 senior and central managers. In this study population census was used and the entire population were considered as the sample. A questionnaire was used for data collection, which included two sections in order to determine the level of research community awareness and to analyze the standards related requirements for the implementation of the system. Validity and reliability were assessed and the data was analyzed by SPSS.

Results: Sample awareness in 5 hospitals of this study was moderate. In terms of requirements, there was a significant difference between the means of Electronic Medical Records in terms of three variables between hospitals "D" and the rest of the hospitals. And no significant difference was seen among other hospitals.

Conclusion : Three hospitals, "a", "c" and "b", among five studied hospitals are in preparation for the deployment of electronic medical records. Other two hospitals were not prepared. However, the implementation of electronic medical records, increases health care quality, patient safety and patient care and also decreases health costs. So it is suggested that hospitals do necessary efforts to establish EMR.


Survey Of Telepathology Implementation Feasibility In The Teaching Hospitals Affiliated To Tehran University Of Medical Sciences
Farahnaz Sadoughi , Malihe Sadeghi , Mostafa Langarizadeh , Elahe Gozali ,
Volume 8, Issue 4 (11-2014)
Abstract

Background and Aim: Tele pathology is one of the medical subdivisions that has opened a new approach in the telepathology, e specially to organize consultations. In this research, feasibility of Telepathology implementation in teaching hospitals of Tehran University of Medical Science was studied.

Materials and Methods: This study was a cross-sectional and descriptive study. The study population was included 8 hospitals directors and administrator, 20 pathologists, and 8 informatics staffs, in four teaching hospitals of Tehran University of Medical Sciences. A researcher constructed questionnaire was used for data collection . The validity of the questionnaire was confirmed by expert panel and using by Test – retest method confirmed its reliability. The data was collected and analyzed by SPSS software to prepare descriptive findings.

Results: The R esults showed that 65.6% of hospitals had hardware facilities . Procedures based on legal issues related to information security and privacy was 95.71%, while t here was no guideline for telemedicine and telepathology.

Conclusion: I t could be concluded that in line with considrating the importance and benefits of telepathology, it is necessary to provide software requirements and hardware infrastructure. It should be noted that available properties also must be improved in terms of implementation of telepathology. Also, rules to support patients’ and staff’s rights should be developed for better implementation of such new technologies


Normetanephrine and Glucose Acute Responses to Aerobic Boxing with Kinect Xbox with and without Blood Flow Restriction as a Strategy against Inactivity in Non-Athletes
Zeinab Sadat Mousavi, Farshad Ghazalian, Mandana Gholami, Hossein Abed Natanzi, Khosrow Ebrahim,
Volume 15, Issue 4 (oct & Nov 2021)
Abstract
Background and Aim: Inactivity increases the risk of chronic diseases. The aim of the present study was to investigate the acute changes in Normetanephrine and glucose in boxing with Kinect Xbox with and without blood flow restriction as an alternative to aerobic exercise during quarantine in young non-athletes.
Material and Methods: Fourteen healthy non-athlete individuals with a range of 20 to 40 years of age were randomly and purposefully selected. And on two different days with and without restriction of blood flow, they played boxing with Xbox 360 for 20 minutes. Blood samples were taken before and immediately after
Results: There was a significant increase in serum Normetanephrine playing compared to before the test in both training groups, but the amount of changes between the two groups with and without blood flow restriction was not significant (P≤0.05). Exergames, in the case of unrestricted blood flow, has a significant effect on glucose, but the restriction of blood flow did not lead to a significant difference in the amount of glucose (P≤0.05).
Conclusion: Exergames provide the necessary stimulus for catecholamine secretion and glucose response, and it is recommended for people with limited blood flow. Further studies are needed on the effect of restricting blood flow as a new training method on video game with movement.

Oncolytics, Cancer-Fighting Viruses from Past to Future: A Literature Review
Seyedeh Nasim Mirbahari, Sina Salari, Shabnam Shahrokh, Mohammadreza Zali, Mehdi Totonchi,
Volume 18, Issue 1 (3-2024)
Abstract
Background and Aim: Oncolytic viruses, as novel and advanced tools in the field of treating various types of cancer, have played a very important role in medical developments. The term “oncolytic” refers to the ability of these viruses to destroy and damage cancer cells while preserving the surrounding healthy cells.
Materials and Methods: To conduct this study, a total of 270 initial results were collected through searching in the PubMed, Scopus, and Google Scholar databases from 2012 to 2024. The primary researcher reviewed 68 relevant articles, extracted and summarized the contents, and finally compiled the findings.
Results: The findings from this review study demonstrate that cancer cells possess distinct characteristics that differentiate them from normal cells, including continuous growth signaling, resistance to anti-growth signaling, evasion of apoptosis, increased angiogenesis, and invasion into other body parts. Oncolytic viruses utilize these distinctive features to selectively target and infect cancer cells. Most oncolytic viruses directly eliminate host tumor cells, resulting in viral replication and induction of host antiviral responses. Moreover, these viruses can destroy cancer cells through the production of specific proteins. The cytotoxic potential of oncolytic viruses depends on viral type, genetic manipulation, optimal virus dosage for injection, natural and induced viral tropism, and cancer cell sensitivity to various forms of cell death. The mechanism driving the selective replication of oncolytic viruses in cancer cells likely relates to defects in signaling pathways specific to tumor cells. Phase III clinical trials have demonstrated significant improvements in the treatment outcomes of various cancers, including head and neck cancer, melanoma, glioblastoma, and bladder cancer, through the use of H101 (Oncorine), T-Vec, ECHO-7, and Teserpaturev (Delytact) viruses.
Conclusion: Oncolytic viruses are constructed from various types of viruses and are currently being evaluated in laboratory, preclinical, and clinical stages. The use of these viruses for the treatment of cancer as a new and targeted approach has been proposed, which requires further investigation and achievement of more precise mechanisms for their better performance.

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