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Sakineh Abbasi, Shahrzad Sharifpour Vajari,
Volume 15, Issue 5 (Dec 2021 & Jan 2022)
Volume 15, Issue 5 (Dec 2021 & Jan 2022)
Abstract
Background and Aim: Cervical cancer is the fourth main cause of mortality among women, and annually about half a million new cases are detected in developed countries. Based on oncological studies, human papillomavirus (HPV) is classified into two categories: high-risk type and low-risk type, and most cases are related to the high-risk type of human papillomavirus. HPV 16 and 18 are among the more dangerous ones in this type of cancer. Human papillomavirus is a small group of uncoated viruses with double-stranded DNA that belong to the papillomaviridae family.
Materials and Methods: In this review study, more than 200 articles related to human papillomavirus and immune system function against this virus were reviewed from 2015 to 2020 and among them, 34 articles related to markers and cytokines in cervical cancer were chosen from Google Scholar, Scopus, and PubMed.
Results: One of In-vitro methods in markers detection , is using vectors to infect dendritic cells to present antigen, increase the expression of markers and mature T cell, which leads to the identification of a variety of markers and cytoklines such as PD, PDL, CD, MHC, FASL, IFN, IL, TLR associated with cervical cancer.
Conclusion: Cervical cancer prevention can reduce the economic as well as the social burden of having the disease in the community. Important cytokines expressed when exposed to HPV include IL-6 and IL-8. Several agonist epitopes with enhanced binding power to the human leukocyte antigen (HLA-A2) A2 class I antigen have been described to enhance cytotoxic T lymphocyte responses and to be used in the development of effective HPV vaccines; this is because it has already been shown that different epitopes of 16 HPVs, such as E6 and E7, are able to elicit human cytotoxic T lymphocyte (CTL) responses by binding to HLA-A2.
Reza Abbasi, Fatemeh Rangraz Jeddi, Shima Anvari, Reza Khajouei,
Volume 16, Issue 3 (Aug 2022)
Volume 16, Issue 3 (Aug 2022)
Abstract
Background and Aim: Hospital managers are one of the key decision-makers in the implementation of health information systems. This study aimed to determine the implementation challenges of health information systems based on the hospital managers’ perspective.
Materials and Methods: This descriptive-analytical study was conducted in 2019 on the hospital managers of three provinces (Kerman, Yazd, Sistan and Baluchestan). Data were collected using a self-administrated questionnaire. The face validity of this questionnaire was approved by experts in health informatics and health information management and its reliability was confirmed by Cronbach’s alpha (α=96.7%). Data were analyzed using SPSS. To investigate the relationship between the mean of each challenge with demographic variables, Pearson, Independent T-test, and ANOVA tests were used.
Results: In this study, the factors related to ignoring the hospital manager’s needs in system selection (1.333 out of 2 points), hardware purchase cost, insufficient user training to using the system (1.238), inadequate manpower and health informatics specialists (1.19), software purchase cost, insufficient financial resources (1.142), high cost of system launching, the lack of integration and interoperability among information systems, lack of support from health care professionals (1.047), and lack of management experience in choosing the best system (one out of 2) had the highest scores (out of 2 points). Also, personnel training costs to work with the system (-0.092) and Lack of improvement in work processes (-0.047) obtained the lowest scores. Data analysis showed that managers with clinical backgrounds considered financial and human challenges more important than non-clinical managers (P<0.031).
Conclusion: The hospital managers believed that financial, human, technical, managerial, and organizational factors are the most important challenges in implementing health information systems in Iran’s hospitals respectively. The health policy-makers and planners at large and small levels can address many of the challenges before implementing systems by focusing on identified priorities.
Materials and Methods: This descriptive-analytical study was conducted in 2019 on the hospital managers of three provinces (Kerman, Yazd, Sistan and Baluchestan). Data were collected using a self-administrated questionnaire. The face validity of this questionnaire was approved by experts in health informatics and health information management and its reliability was confirmed by Cronbach’s alpha (α=96.7%). Data were analyzed using SPSS. To investigate the relationship between the mean of each challenge with demographic variables, Pearson, Independent T-test, and ANOVA tests were used.
Results: In this study, the factors related to ignoring the hospital manager’s needs in system selection (1.333 out of 2 points), hardware purchase cost, insufficient user training to using the system (1.238), inadequate manpower and health informatics specialists (1.19), software purchase cost, insufficient financial resources (1.142), high cost of system launching, the lack of integration and interoperability among information systems, lack of support from health care professionals (1.047), and lack of management experience in choosing the best system (one out of 2) had the highest scores (out of 2 points). Also, personnel training costs to work with the system (-0.092) and Lack of improvement in work processes (-0.047) obtained the lowest scores. Data analysis showed that managers with clinical backgrounds considered financial and human challenges more important than non-clinical managers (P<0.031).
Conclusion: The hospital managers believed that financial, human, technical, managerial, and organizational factors are the most important challenges in implementing health information systems in Iran’s hospitals respectively. The health policy-makers and planners at large and small levels can address many of the challenges before implementing systems by focusing on identified priorities.
Marjan Ghazi Saeedi, Mohammad Amin Abbasi Eslamloo, Kobra Darabiyan, Elham Ataei,
Volume 17, Issue 3 (8-2023)
Volume 17, Issue 3 (8-2023)
Abstract
Background and Aim: Despite the continuous progress in medicine, COPD (Chronic Obstructive Pulmonary Disease) is still a progressive, incurable and chronic respiratory condition that limits the patients’ functions in various dimensions, and significantly reduce their quality of life. In this way, self-care of patients and the use of related tools have a significant effect in disease control and treatment. The purpose of this research was design and development of an android-based application for COPD.
Materials and Methods: This research was a descriptive developmental type with a practical approach. Initially, based on the study of library resources, guidelines, and the examination of the medical records of COPD inpatients in Firouzabadi Hospital, a questionnaire was designed to identify the information requirements, data items and features of the application. Then it was reviewed and finalized by a sample of 10 (randomized and convenience sampling) internal and lung specialist doctors in Firouzabadi and Hazrat Rasool hospitals affiliated to Iran University of Medical Sciences. The data was analyzed using descriptive statistics, and then scenario tables and UML diagrams were illustrated to show the overall flow of the application. The application was designed and developed using the Java programming language in the Android Studio 2021 platform. After installing the application on the mobile phones of ten COPD patients of the internal and pulmonary clinic of Firouzabadi Shahre Rey Hospital, and using it for a week, the opinions of the patients about the usability of the application were collected through the QUIS questionnaire, and analyzed.
Results: Application sections were determined following experts’ survey, personal information items, clinical information, disease management, reporting, and training points, which were provided to patients after design for use and evaluation. At the end of the research, the results of the evaluation of the usability and satisfaction level of the application showed that from the patients’ point of view, the application is at a good level with an average score of 1.8 (out of 10 points).
Conclusion: The developed self-care application can be used to increase awareness, help to manage the disease, increase the level of quality of life, and reduce the complications and disease burden for patients with COPD.
Materials and Methods: This research was a descriptive developmental type with a practical approach. Initially, based on the study of library resources, guidelines, and the examination of the medical records of COPD inpatients in Firouzabadi Hospital, a questionnaire was designed to identify the information requirements, data items and features of the application. Then it was reviewed and finalized by a sample of 10 (randomized and convenience sampling) internal and lung specialist doctors in Firouzabadi and Hazrat Rasool hospitals affiliated to Iran University of Medical Sciences. The data was analyzed using descriptive statistics, and then scenario tables and UML diagrams were illustrated to show the overall flow of the application. The application was designed and developed using the Java programming language in the Android Studio 2021 platform. After installing the application on the mobile phones of ten COPD patients of the internal and pulmonary clinic of Firouzabadi Shahre Rey Hospital, and using it for a week, the opinions of the patients about the usability of the application were collected through the QUIS questionnaire, and analyzed.
Results: Application sections were determined following experts’ survey, personal information items, clinical information, disease management, reporting, and training points, which were provided to patients after design for use and evaluation. At the end of the research, the results of the evaluation of the usability and satisfaction level of the application showed that from the patients’ point of view, the application is at a good level with an average score of 1.8 (out of 10 points).
Conclusion: The developed self-care application can be used to increase awareness, help to manage the disease, increase the level of quality of life, and reduce the complications and disease burden for patients with COPD.
Reza Dehkhodaei, Mazyar Karamali, Mohammad Mohammadian, Mohammadkarim Bahadori, Mohsen Abbasifarajzadeh,
Volume 17, Issue 6 (2-2024)
Volume 17, Issue 6 (2-2024)
Abstract
Background and Aim: Considering the importance of knowledge management in the current era and the emphasis on the implementation of knowledge management in the health system in the knowledge management system of the Ministry of Health, Treatment and Medical Education, and since it is one of the first steps in the implementation of knowledge management, Drawing the knowledge tree of the organization, the purpose of the current research is to review the process of publishing the knowledge tree and examine it in the field of health.
Materials and Methods: The current research is a type of applied and descriptive review study that was carried out with the method of scientometrics and co-occurrence analysis of keywords. For this purpose, the term “Knowledge tree” OR “knowledge trees” was searched in Scopus reference database. For data analysis, the analyzes provided by the database itself were used, and VOSviewer software was used to visualize the data.
Results: The growth of scientific productions related to the field of the tree of knowledge in general in the mentioned base has started since 1979 and has had a growing trend until 2023. In the field of knowledge tree, among the authors Yang, Y, among the organizations, machine intelligence institute, iona college, and among the countries, China, America, and England have been at the top of the most productive in this field. Among the subjects, the most related articles are primarily related to the field of computer science (32.2 percent) and then to the field of engineering (22.1 percent) and mathematics (10.1 percent), which is significant. that medicine is in the sixth place and this is a sign of the weakness of producing resources in this field and the clustering resulting from the co-occurrence of keywords led to the identification of five clusters respectively with the titles of data mining and information processing, artificial intelligence and expert systems. , knowledge structure and decision support systems, semantics and knowledge representation, and finally learning and teaching systems.
Conclusion: The study of the thematic structure of scientific productions in the field of Knowledge Tree showed that the field of health has a weakness in the production of resources in this field. Therefore, it is necessary for future researches to pay special attention to the development and explanation of this concept and modeling its drawing, especially in the health system, in order to identify and prevent diseases.
Ali Mohammad Mosadeghrad, Mahdiyeh Heydari, Mahya Abbasi, Mahdi Abbasi,
Volume 18, Issue 2 (12-2024)
Volume 18, Issue 2 (12-2024)
Abstract
Background and Aim: Health insurance organizations play an important role in increasing people’s access to health services and protecting them financially against catastrophic health costs. Iran Health Insurance Organization (IHIO) is one of the largest public health insurance organizations in Iran, which faces many challenges. The purpose of this research is the strategic analysis of health financing performance of IHIO.
Materials and Methods: This qualitative research was conducted using interpretive phenomenology method through using semi-structured interviews with 25 managers and employees of IHIO. In addition, relevant documents and archival data of IHIO were collected and analyzed. Thematic analysis method was used to analyze the data.
Results: Overall, 19 strengths, 24 weaknesses, 14 opportunities, 37 threats and 43 solutions were identified for the health financing system of IHIO. Increasing the coverage of health services, correcting the information databases of the insured and electronic prescribing were the most important strengths, and inappropriate pooling of financial resources, incomplete risk pooling, high administrative costs, and inefficient control were the most important weaknesses of IHIO. The most important opportunities for IHIO include the government’s support for universal health coverage and emphasis on primary health care, legal support for consolidating health insurance funds and improving the health technology assessment system in the country. The main threats to IHIO include political and economic unstability, low health insurance premiums, decisions without scientific support and insufficient enforcement of laws. Finally, solutions such as modernizing the tax system, increasing the health literacy of the community, reducing bureaucracy, increasing transparency and accountability, and reforming the monitoring and evaluation system were identified to strengthen the performance of the financing system of IHIO.
Conclusion: Iran’s health insurance organization is facing numerous structural, contexual and process challenges that have reduced its productivity. Decrease in revenues, increase in costs and decrease in efficiency have caused problems in the financing performance of this organization. Recognizing the weaknesses and challenges of financing performance and applying corrective interventions is the first step in strengthening the sustainability of health financing of IHIO.
Materials and Methods: This qualitative research was conducted using interpretive phenomenology method through using semi-structured interviews with 25 managers and employees of IHIO. In addition, relevant documents and archival data of IHIO were collected and analyzed. Thematic analysis method was used to analyze the data.
Results: Overall, 19 strengths, 24 weaknesses, 14 opportunities, 37 threats and 43 solutions were identified for the health financing system of IHIO. Increasing the coverage of health services, correcting the information databases of the insured and electronic prescribing were the most important strengths, and inappropriate pooling of financial resources, incomplete risk pooling, high administrative costs, and inefficient control were the most important weaknesses of IHIO. The most important opportunities for IHIO include the government’s support for universal health coverage and emphasis on primary health care, legal support for consolidating health insurance funds and improving the health technology assessment system in the country. The main threats to IHIO include political and economic unstability, low health insurance premiums, decisions without scientific support and insufficient enforcement of laws. Finally, solutions such as modernizing the tax system, increasing the health literacy of the community, reducing bureaucracy, increasing transparency and accountability, and reforming the monitoring and evaluation system were identified to strengthen the performance of the financing system of IHIO.
Conclusion: Iran’s health insurance organization is facing numerous structural, contexual and process challenges that have reduced its productivity. Decrease in revenues, increase in costs and decrease in efficiency have caused problems in the financing performance of this organization. Recognizing the weaknesses and challenges of financing performance and applying corrective interventions is the first step in strengthening the sustainability of health financing of IHIO.
Kourosh Abbasiyan, Mohammad Alimoradnori, Mohammad Bagher Karami,
Volume 18, Issue 2 (12-2024)
Volume 18, Issue 2 (12-2024)
Abstract
Background and Aim: Managers, as the main decision-makers in facing various internal and external organizational problems, play a significant and determining role in the success or even failure of an organization. If competent and experienced managers are positioned at the top of organizations, the success of these organizations in achieving their goals will be guaranteed and an organization can achieve maximum efficiency with minimal resources. The aim of this study was to design a model of managerial competencies for hospital managers.
Materials and Methods: This qualitative research was conducted from year 2020 to 2022. After reviewing studies related to the topic, the extracted competencies were given to 19 experts consisted of relevant academic faculty members and managers with experience in the healthcare system and hospitals. Eventually, a managerial competency model was formulated through the use of the Delphi method and expert panel discussions. Collected data were analyzed in Excel software.
Results: The developed model in this research for the concept of hospital managers’ competencies includes 33 managerial competencies of hospital managers in four main management functions (planning, organizing, leadership and control) and managerial roles, which starts from literature review and performing two Delphi steps and implementing two expert panel plans. In the competency of hospital managers model, the planning dimension consists 4 components, organizing consists 4 components, leadership consists 12 components, control consists 4 components, and managerial roles consists 9 components. Strategic thinking, which is a subset of planning, has the highest weight (0.495) and highest rank among other components, and continuous improvement, which is a subset of managerial roles, has the lowest weight (0.033) and lowest rank among other components.
Conclusion: This study proposes an exclusive and comprehensive model, utilizing practical techniques as a suitable solution for evaluating the managerial competencies of hospital managers. The proposed framework in this study can serve as a standard performance assessment tool for evaluating managers.
Materials and Methods: This qualitative research was conducted from year 2020 to 2022. After reviewing studies related to the topic, the extracted competencies were given to 19 experts consisted of relevant academic faculty members and managers with experience in the healthcare system and hospitals. Eventually, a managerial competency model was formulated through the use of the Delphi method and expert panel discussions. Collected data were analyzed in Excel software.
Results: The developed model in this research for the concept of hospital managers’ competencies includes 33 managerial competencies of hospital managers in four main management functions (planning, organizing, leadership and control) and managerial roles, which starts from literature review and performing two Delphi steps and implementing two expert panel plans. In the competency of hospital managers model, the planning dimension consists 4 components, organizing consists 4 components, leadership consists 12 components, control consists 4 components, and managerial roles consists 9 components. Strategic thinking, which is a subset of planning, has the highest weight (0.495) and highest rank among other components, and continuous improvement, which is a subset of managerial roles, has the lowest weight (0.033) and lowest rank among other components.
Conclusion: This study proposes an exclusive and comprehensive model, utilizing practical techniques as a suitable solution for evaluating the managerial competencies of hospital managers. The proposed framework in this study can serve as a standard performance assessment tool for evaluating managers.
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