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Showing 726 results for Type of Study: Original Research

Mashallah Torabi, Sara Naeimi, Elnaz Vahedi, Hamideh Hamidi,
Volume 17, Issue 6 (2-2024)
Abstract

Background and Aim: Educating the audience is one of the things that can affect their mental perception of the usefulness and ease of utilizing technology. Due to the lack of knowledge about the unique features and ease of use of Tehran University of Medical Sciences website, some audiences prefer to use the old website and do not accept the changes on the university website well. This research was conducted with the aim of comparing the two methods of face-to-face training and clip training in accepting information technology changes on the university website and evaluating the audience’s awareness of branding features on the web.
Materials and Methods: There were 90 people who participated in this study, 45 of whom received face-to-face training and 45 of them received training about site changes through video clips. Research data collection was done based on Davis questionnaire and data analysis was done using SPSS and Padprism graph software. To compare a quantitative variable in more than two groups, one-way analysis of variance test or Kruskal-Wallis test and also, and also, one-way ANCOVA test were used to check the difference between groups before and after training.
Results: In face-to-face training, variables such as awareness, usefulness and perceived ease of use, as well as attitude and performance regarding the use of information technology before and after face-to-face training or clip did not have significant differences.
Conclusion: Examining the effectiveness of the teaching methods in this project will help the public relations of the university to act quickly for the changes that will occur in the field of web branding in the future, in terms of preparing and accompanying the audience.

Maryam Andalib Kondori, Ahmadreza Varnaseri, Maryam Ghanbari Khoshnood, Seyed Abedin Hoseini Ahangari, Mohammad Karim Saberi, Hamid Bourghi,
Volume 17, Issue 6 (2-2024)
Abstract

Background and Aim: This research aimed to study the status of providing health information services in public libraries in Tehran, which was conducted based on the views of librarians working in these libraries.
Materials and Methods: The research method was applied in terms of its purpose and descriptive in terms of data collection, which was conducted as a survey. The statistical population was 150 librarians of public libraries in Tehran. The tool for collecting information was a researcher-made questionnaire. Data analysis was done using SPSS statistical software..
Results: The status of health information resources available in public libraries of Tehran is low and very low in most sources. The level of familiarity of librarians with health and public health issues is %20. The level of familiarity of librarians with selective dissemination of health information services is low and very low with %77.4. The participation rate of librarians in medical information workshops is faced with the non-participation of %70 of librarians. The familiarity of librarians with the services of selective distribution of health information is low and very low. %60 of librarians are not familiar with medical information systems. The percentage of familiarity of librarians with internal medical websites is %60-78 weak. The percentage of familiarity of librarians with foreign international websites in the field of health is average. Librarians consider the main reason for providing selective health information services to improve the level of health literacy in the society. Also, the main obstacle to providing health information dissemination services is the librarian not having enough time to provide services.
Conclusion: The country’s public libraries should consider measures to familiarize librarians with the field of health information and implement policies in this field. Considering the appropriate technical facilities of public libraries in Tehran, it is possible to create and access internal and external health systems and websites. and expanded the sources and documents of librarians’ health information.

Parisa Moradimajd, Shahnam Sedighmaroufi, Shaqayeq Taghizadeh, Mr Jamileh Abolghasemi, Alireza Babajani,
Volume 18, Issue 1 (3-2024)
Abstract

Background and Aim: One of the basic principles in the safety of drug therapy for patients is the correct registration and labeling of anesthetic drugs, which can lead to the reduction of drug errors, the increase of drug and patient safety, the reduction of drug consumption and the environment, and the optimization of hospital costs.
Materials and Methods: This descriptive-analytical and cross-sectional research was conducted in February 2022 in the operating rooms of Iran University of Medical Sciences hospitals. The participants included 177 Anesthesia experts working in the hospitals’ operating rooms, who were included in the study by census method. The data was collected using the checklist for evaluating anesthetic drug registration and labeling guidelines and analyzed using SPSS software and one-way ANOVA, Fisher, and Pearson correlation coefficient statistical tests. The significance level was considered P value < 0.05.
Results: The average compliance with the guidelines for registration and labeling of anesthetic drugs in all hospitals was 3.559 out of the total score of 16. The average adherence to guidelines in 8 hospitals was significantly different from each other (P < 0.001). Hazrat Ali Asghar Hospital had the highest compliance rate, averaging 10.333 out of 16. Firouzgar and Shahid Akbarabadi hospitals were in the next rank, averaging 10.11 and 6.65, respectively. There was a negative and significant correlation between the level of compliance with the guidelines and the average work experience and age of the experts (P=0/17); However, gender did not significantly correlate with the degree of adherence to the guidelines(P=0/596).
Conclusion: According to the obtained results, compliance with the guidelines for registration and labeling of anesthetic drugs in most hospitals was assessed as weak and at an unfavorable level. Considering the importance of this issue in reducing medication errors and increasing patient safety, it is necessary to use empowerment and retraining courses for Anesthesia experts according to the latest guidelines.

Hassan Zarghani, Masoud Jabbari, Sajjad Pandesh,
Volume 18, Issue 1 (3-2024)
Abstract

Background and Aim: X-ray radiation, besides its useful applications in the diagnosis and treatment of diseases, also has harmful effects. With the increasing demand for various radiographs and X-ray imaging, radiation protection for radiographers is of particular importance. In this regard, a study was conducted to examine the level of awareness, attitude, and performance of radiographers in Iran with regards to the effects of ionizing radiation and protective methods against them.
Materials and Methods: In this descriptive-analytical study, based on a census, the awareness, attitude, and performance of radiographers in 52 cities in Iran were examined by using a questionnaire. Data from 847 radiographers were collected. Finally, the data were analyzed using t-test and analysis of variance through SPSS  statistical software.
Results: Out of the total distributed questionnaires (748 items), 531 questionnaires were completely filled by radiation workers. In the present study, 46% were male and 53% were female, with average scores related to the awareness, attitude, and performance of radiographers in the field of radiation protection being 59.9, 69.4, and 43.54, respectively. There was no statistically significant difference (P<0.05) between the awareness levels of individuals who had undergone refresher training (24.3%) and those who had not. Radiographers’ knowledge of specialized information such as the principle of As Low as Reasonably Available (ALARA) (68.5%), Bucky factor (65.5%), and heel effect (61%), alongside the relationship between source-to-skin distance and radiation intensity (71%), was at a moderate level.
Conclusion: The poor performance of radiologists in this study is not solely attributed to functional deficiencies but sometimes also involves the institutionalization of incorrect principles. These weaknesses and shortcomings are undoubtedly the result of inadequate supervision and erroneous modeling over a long period. If not addressed, they will undoubtedly have irreparable destructive consequences in the future, especially with the increasing advancement of diagnostic radiology methods.

Seyed Mohammad Sadegh Dashti, Amid Khatibi Bardsiri, Mehdi Jafari Shahbazzadeh,
Volume 18, Issue 1 (3-2024)
Abstract

Background and Aim: Medical reports and electronic health records are critically important for diagnosis, treatment, patient protection, and medical research. Correcting spelling errors in medical texts is essential to ensure accurate interpretation of information. This research was conducted to automatically correct spelling mistakes in Persian medical texts using neural networks.
Material and Methods: In this study, which was conducted in 2023, a computational model based on artificial intelligence neural networks and dual embedding techniques was developed using Python in a Windows environment. The dual embedding model was fine-tuned for correcting spelling errors in Persian sonography texts. The proposed model employs various techniques for automatic error detection, including dictionary lookup approach and contextual similarity coefficients. Furthermore, features specific to text processing, such as Edit-Distance, along with similarity coefficients, were utilized to automatically select the most appropriate substitute for a misspelled word. The training and testing data for the current model were sourced from a collection of sonography texts from the Imam Khomeini Hospital’s sonography clinic in Tehran.
Results: The proposed model which is based on artificial neural networks, leverages a novel dualembedding architecture to select the best candidate words for correcting both non-word and real-word errors. According to the evaluation results on Persian sonography text, the proposed model achieved an F-Measure accuracy of 90.5% in detecting real-word errors. Furthermore, it demonstrated an impressive 90% accuracy in automatically correcting these real-word errors. Additionally, the model exhibited a strong performance, achieving 90.8% accuracy in correcting non-word errors.
Conclusion: Based on the evaluation results, the proposed method is robust against various changes in word forms and can effectively manage a wide range of morphological and semantic errors, including replacements, transpositions, insertions, and deletions in medical texts. The integration of EditDistance with textual similarity coefficients extracted from the dual embedding model significantly enhanced the accuracy of spelling corrections in Persian sonography texts, ensuring greater validity of such documents. The authors believe that the proposed model represents a significant advancement in the detection and correction of spelling errors in Persian sonography texts.

Shahnaz Khademizadeh, Bahram Peymannia, Fatemeh Rafieinasab,
Volume 18, Issue 1 (3-2024)
Abstract

Background and Aim: The term “information behavior,” with an emphasis on health and hygiene, refers to purposeful actions taken to satisfy informational needs related to health. The objective of the current research is to develop and validate a questionnaire on information behavior, with a focus on health and hygiene information.
Materials and Methods: This study was a quantitative research conducted with a tool design approach. Initially, a questionnaire for measuring this behavior was prepared using instrument design methods. The basis for extracting the factors of the present questionnaire has been argumentation and logical repetition. In other words, the researcher, in line with the background of these factors and their repetition in the sources, used them as influential factors in the questionnaire construction. After confirming the content and structural validity, the modified questionnaire was distributed among 238 patients with multiple sclerosis. The sample selection.
was done using the available sampling method. Then, the data were analyzed using exploratory and confirmatory factor analysis. The internal consistency of the data was calculated using Cronbach’s alpha. The collected data were analyzed using descriptive and inferential statistical methods with the help of SPSS and AMOS software.
Results: The content validity of the questionnaire was evaluated with the opinion of 20 experts in information behavior. The reliability of the health information behavior questionnaire was adequate and satisfactory with the overall Cronbach’s alpha coefficient of 0.78 and the Cronbach’s alpha coefficient of the components between 0.71 and 0.94. In order to factor analysis, the sampling adequacy index and the value of Bartlett’s Crowley test were calculated, and all 29 items were statistically significant; which confirms the factorization of the correlation matrix. In the exploratory factor analysis, five factors (avoidance of information), the second factor (need for information), the third factor (exposure to information), the fourth factor (seeking information), and the fifth factor (use of information) were obtained. The indicators of confirmatory factor analysis showed the validity of the proposed structure. The results of the structural equation model test showed that the fit indices were favorable and also indicated the fit of the presented model in the MS patient population.
Conclusion: The obtained results demonstrated that health information behavior in this questionnaire encompasses five factors: information needs, information-seeking behavior, information avoidance, information use, and information confrontation, which were confirmed. The designed scale for assessing health information behavior in the Iranian community has been evaluated and is recommended for use in measuring health information behavior effectively.

Mehdi Raadabadi, Zahra Tolideh, Zahra Shoara, Zahra Yeganeh, Jamil Sadeghifar, Khalil Momeni,
Volume 18, Issue 1 (3-2024)
Abstract

Background and Aim: There is limited evidence about the effect of the corona disease epidemic on the efficiency of hospitals in Iran. This study was conducted with the aim of investigating the effect of the Covid-19 epidemic on the productivity of public hospitals in Ilam province.
Materials and Methods: This retrospective descriptive research has investigated the performance of 9 hospitals in Ilam province during a four-year period(1397-1400) based on the Pabon Lasso graphic model. The desired data were extracted from the HIS system of the hospitals and the key performance indicators of BOR, BTR and ALOS were calculated. The Pabon Lasso diagram was drawn with Excel software.
Results: The results showed that the bed occupancy percentage in teaching hospitals is significantly higher than non-teaching hospitals (P<0.05). Based on the results, the percentage of bed occupancy and the rate of bed rotation after the covid 19 pandemic has decreased significantly (P<0.05). The average length of the stay of patients also increased after the pandemic (P<0.05). Overall evaluation of hospital efficiency based on the Pabén Lasso model shows that the frequency of hospitals located in Nakara district has decreased from 4 hospitals before the pandemic to 3 hospitals, although hospitals in Kara district have not changed during this period.
Conclusion: Most of the researched hospitals, especially non-teaching hospitals, have low bed occupancy. Weakness in the service delivery chain, especially diagnostic services and specialized and super-specialized services, is one of the main reasons for this situation. Moving towards a change in the way hospitals are managed and having more flexibility in the structure and implementation in the short term and prioritizing large hospitals with a complete chain of services can lead to a way out of the current inefficient situation.

Bizhan Hooshmand Moghadam, Shadi Moazami Goudarzi, Amir Rashid Lamir,
Volume 18, Issue 1 (3-2024)
Abstract

Background and Aim: Adipokines imbalance causes pathological effects on this system. Exercise interventions can play an important role in regulating the secretion of adipokines. This study aimed to investigate the effect of 12 weeks of resistance training on the serum level of apelin, vaspin, and blood pressure in elderly men with hypertension.
Materials and Methods: In this quasi-experimental study, 24 elderly men with high blood pressure were selected purposefully and based on the inclusion criteria and were randomly assigned to resistance training (N=12) and control (N=12) groups. The participants of the resistance training group performed resistance training for 12 weeks and three days a week. At the beginning and end of the study, blood samples were collected to measure the serum level of apelin and vaspin. Data analysis was performed using SPSS version 24 software with dependent and independent t-tests at a significant level of less than 0.05.
Results: After 12 weeks of resistance training, there was a significant decrease in the serum level of apelin (P=0.002), vaspin (P=0.01), systolic blood pressure (P<0.001), and diastolic blood pressure (P<0.001) as compared to the pre-test. In addition, a significant difference was observed between the two experimental and control groups in the serum level of apelin (p=0.001), vaspin (P=0.001), systolic blood pressure (P<0.001), and diastolic blood pressure (P<0.001).
Conclusion: It seems 12 weeks of resistance training can improve systolic and diastolic blood pressure and regulate the secretion of adipokines apelin and vaspin in elderly men with high blood pressure.

Ali Mohammad Mosadeghrad, Mahdiyeh Heydari, Mahya Abbasi, Mahdi Abbasi,
Volume 18, Issue 2 (5-2024)
Abstract

Background and Aim: Health insurance organizations play an important role in increasing people’s access to health services and protecting them financially against catastrophic health costs. Iran Health Insurance Organization (IHIO) is one of the largest public health insurance organizations in Iran, which faces many challenges. The purpose of this research is the strategic analysis of health financing performance of IHIO.
Materials and Methods: This qualitative research was conducted using interpretive phenomenology method through using semi-structured interviews with 25 managers and employees of IHIO. In addition, relevant documents and archival data of IHIO were collected and analyzed. Thematic analysis method was used to analyze the data. 
Results: Overall, 19 strengths, 24 weaknesses, 14 opportunities, 37 threats and 43 solutions were identified for the health financing system of IHIO. Increasing the coverage of health services, correcting the information databases of the insured and electronic prescribing were the most important strengths, and inappropriate pooling of financial resources, incomplete risk pooling, high administrative costs, and inefficient control were the most important weaknesses of IHIO. The most important opportunities for IHIO include the government’s support for universal health coverage and emphasis on primary health care, legal support for consolidating health insurance funds and improving the health technology assessment system in the country. The main threats to IHIO include political and economic unstability, low health insurance premiums, decisions without scientific support and insufficient enforcement of laws. Finally, solutions such as modernizing the tax system, increasing the health literacy of the community, reducing bureaucracy, increasing transparency and accountability, and reforming the monitoring and evaluation system were identified to strengthen the performance of the financing system of IHIO.
Conclusion: Iran’s health insurance organization is facing numerous structural, contexual and process challenges that have reduced its productivity. Decrease in revenues, increase in costs and decrease in efficiency have caused problems in the financing performance of this organization. Recognizing the weaknesses and challenges of financing performance and applying corrective interventions is the first step in strengthening the sustainability of health financing of IHIO.

Hanie Pooshideh, Jalal Jafarzade, Ali Heidarpour, Mojtaba Taghizade Armaki, Saeid Mahdavi Omran, P.h.d Firoozeh Kermani, Mohsen Karami,
Volume 18, Issue 2 (5-2024)
Abstract

Background and Aim: Cockroaches are potential carriers of a wide range of pathogenic microorganisms (fungi, bacteria and parasites). Considering the importance of these insects in the transmission of pathogenic fungi and their impact on the health of hospitalized people, the aim of this study was isolation and molecular identification of pathogenic fungi from the external and internal surfaces of cockroaches collected from three educational hospitals of Babol city, Mazandaran Province, Iran.
Materials and Methods: Cockroaches were caught by a sterile manual method and after washing to remove surface contamination with 70% ethyl alcohol for 2min, 100 µL of the solutions from the external and internal parts of cockroaches were cultured on Sabouraud’s dextrose agar with 0.05% chloramphenicol and incubated at 30 °C for 3 weeks. The different yeast and filamentous colonies were distinguished using standard mycological methods. The PCR-RFLP method and the restriction enzymes Msp I and Bln I were used for the differentiation of Candida species, and the restriction enzyme Alw I for Aspergillus species.
Results: A total of 85 fungi species/genera were isolated from all 50 studied cockroaches, including German cockroaches 15 (30%), American cockroach 20 (40%) and brown 15 (30%), which included 52 isolates from external surfaces (61%) and 33 isolates from internal surfaces of cockroaches (39%). Of the total number of 49 filamentous fungi, Aspergillus fumigatus 16 (32.65%) and out of the total number of 36 yeasts identified, Candida albicans 14 (38.89%) were the most common fungi isolated in this study. Other filamentous fungi and yeasts isolated from cockroaches include Aspergillus niger 11 (22.45%), Aspergillus flavus 8 (16.32%), Penicillium 4 (8.2%), Rhizopus 3 (6.1%), Cladosporium 3 (6.1%), Mucor 2 (4%), Alternaria 2 (4%), Candida parapsilosis 6 (16.67%), Candida krusei 12 (33.33%), Candida glabrata 3 (8.33%), and Candida tropicalis 1 (2.78%) were isolated.
Conclusion: Considering the isolation of several fungal species from cockroaches and their importance in the possible mechanical transmission of common fungal infections in hospitals, these insects can be a source of continuous transmission of infection, if there is no regular preventive disinfection of the hospital environment.

Sedigheh Mohammadesmaeili, Nahid Ramzanghorbani, Shiba Kianmehr,
Volume 18, Issue 2 (5-2024)
Abstract

Background and Aim: Passive smoking is known to have an impact on the respiratory system of infants and children. The aim of this study is to examine the positive effects of parental smoking cessation programs using nicotine replacement on quality of life in children with asthma at the Children's Medical Center of Tehran University of Medical Sciences.
Materials and Methods: This case-control study included 100 children aged 6-10 years with asthma who had their parents smoking in the Allergy Department of the Children's Medical Center of Tehran University of Medical Sciences. During the 2019-2021 period, this study was conducted using a census as the sampling method. Data were collected using standard questionnaires of the Child Health-Related Quality of Life (HRQoL), standard versions of the Short Form (SF-12) and the St George Respiratory Questionnaire (SGRQ). The two groups were compared using independent t-tests and paired t-tests, and Pearson's correlation coefficient was utilized to examine the correlation between the two questionnaires. Statistical analysis was performed using SPSS software.
Results: Children with asthma who had their parents quit smoking had a mean score lower than those who did not intervene. This indicates that the quality of life in children with asthma whose parents underwent nicotine replacement program improved significantly (P=0.03). Nicotine gum consumption can enhance certain aspects of health-related quality of life for both parents and children, as assessed by SF-12 and SGRQ, according to the results. Physical functioning (P=0.007) and school performance (P=0.002) were the two components most significantly affected.
Conclusion: The physical health and quality of life of parents are can affecte children with asthma, who face many challenges in meeting their daily needs. Smoking cessation using nicotine gum can improve the quality of life of parents and children. To maximize the effectiveness of parental smoking cessation information therapy programs for children with asthma, providing personalized support and advice to parents or caregivers, evidence-based treatments, and educating families on how to manage this disease in children seems essential.

Malihe Ghanaatjoo, Nader Jahanmehr, Dr. Hamed Dehnavi, Aida Samadi,
Volume 18, Issue 2 (5-2024)
Abstract

Background and Aim: The increase in the amount of information and the need for their daily monitoring have led to the development of tools called management dashboards that have the ability to analyze graphical data. In addition to preparing quick reports in different time frames and user-specific format, the dashboard can be useful for providing dynamic updated information for accurate decision-making and quick response to changes.
Materials and Methods: The current research was carried out in the form of qualitative studies and participatory action research method in 9 steps. In this applied and developmental research that was conducted cross-sectionally using the data of the first half of 2022, 11 members of the leadership team of a super-specialized children’s hospital were selected as research participants. The data collection tool was an interview using a questionnaire to determine the importance of indicators and a usability questionnaire (usability) of the dashboard based on three independent variables (usefulness, ease of use and satisfaction). The Excel file of data needed for the dashboard was collected from the HIS system of the hospital, and the dashboard was designed with Power BI software, and the capabilities and access levels of users were determined based on their duties. Data analysis was done using descriptive statistics and Excel software version 2016.
Results: In the stage of determining key performance indicators, out of 39 indicators selected by the research team, 22 indicators scored an average score of 4 or higher (from 5 points) and 21 indicators were able to be implemented. The data repository in Excel format was used as an intermediate environment. The dashboard was displayed on six pages (indicators related to the performance of inpatient beds, mortality, emergency and other indicators) and the capabilities of each page were determined. After implementing the dashboard and determining the access levels of users, obtaining a high score from the questions of the usability questionnaire (5 out of 7 points) and obtaining an average score of 71.8 out of 5 questions related to usefulness variables, 70.5 out of 8 questions related to ease of use. And 71 out of 3 questions related to the satisfaction variable showed that the dashboard designed for the hospital had high usability.
Conclusion: Hospital management dashboard information can be a basis for informed decision-making to achieve benefits such as identifying the best performance, improving performance quality, making faster decisions, reducing errors, improving capacity management and work flow, allocating resources and planning for growth and development. 

Fatemeh Mirshekari, Elham Maserat,
Volume 18, Issue 2 (5-2024)
Abstract

Background and Aim:  Considering the growing trend of cancer in Iran, the development and implementation of digital health literacy systems accelerates the capabilities of digital health and the self-management process of patients. Digital health literacy means the ability to effectively and consciously use digital technologies to access health-related information and services. This skill plays an important role in accessing medical information, disease management, improving the quality of life of people, especially cancer patients. Digital health literacy is considered as one of the most key factors of equal access to digital health information. The purpose of the present study was to formulate the requirements of the digital health literacy system with a focus on cancer.
Materials and Methods: The present study was conducted in two phases of literature review and validity and reliability of requirements in 2023. In the first stage, a literature review was conducted with the keywords of digital health literacy, cancer, requirements, system and application in databases such as PubMed, Scopus, Google Scholar, academic Jihad scientific database and specialized websites. To check the content validity of the survey, 62 experts were surveyed and CVI and CVR were calculated.
Results: Hundered and twenty seven functional and non-functional components were approved. Requirements in the functional section was divided in six main dimensions information literacy module (8 functional components), information and communication technology literacy module (18 functional components), media literacy (5 functional components), public, specialized and population-oriented health literacy module (47 functional components) ), digital health literacy module (28 functional components), and digital health literacy module in cancer (6 functional components) were divided. In the section of digital health literacy in cancer, the main components of needs assessment, digital health literacy training, evaluation and monitoring of the effectiveness of digital interventions and information search skills were approved. Fifteen non-functional components were also approved. Cronbach’s alpha coefficient obtained (92%) indicated high reliability and reproducibility.
Conclusion: Digital health literacy systems can facilitate health care services. Considering the acceptable validity and reliability of the study, the defined requirements can be used to implement digital health literacy systems centered on cancer.

 

Mina Shirvani, Mostafa Roshanzadeh, Maryam Rabiey Faradonbeh, Razieh Mirzaeian,
Volume 18, Issue 2 (5-2024)
Abstract

Background and Aim: Nursing students are exposed to various educational, family, and social stresses and various factors can affect their mental health. Therefore, in order to pay attention to different dimensions of health and investigate the effects of spirituality on health, the present study was conducted to determine the effect of fasting on the mental health of nursing students of Borujen Faculty of Medical Sciences.
Materials and Methods: The present semi-experimental study with a pre-test-post-test design was conducted in 2022 at Shahrekord University of Medical Sciences. Ninety nursing students of Borujen Faculty of Medical Sciences were selected by available methods and assigned to two intervention and control groups by a simple random method. The intervention in this study included at least 23 days of fasting during Ramadan. The data before and after the intervention were collected by the demographic information questionnaire and the 21-question depression, anxiety, and stress standard tool (DASS). The validity and reliability of this questionnaire were conducted for the first time in Iran by Sahebi et al. in 2005. SPSS  was used for analysis. Descriptive statistical tests including frequency percentage, mean and standard deviation, and inferential statistical tests including t-test, paired t-test, analysis of variance, and chi-square were used.
Results: There was no significant difference in the total mental health score between intervention (32.32±11.62) and control (29.87±14.09) groups before the intervention (P=0.08). There was a significant difference in this score between intervention (20.6±5.71) and control (29.49±8.9) groups after the intervention (P=0.04). The total mental health score in the control group before (29.87±14.09) and after (29.49±8.9) the intervention had no significant difference (P=0.15); while in the intervention group before (32.32±11.62) and after (20.6±5.71) the intervention had a significant difference (P=0.001). Mental health dimensions before and after intervention, indicated that anxiety (P=0.04) and stress (P=0.003) decreased significantly after the intervention in the intervention group. However, there was no significant difference in the depression dimension (P=0.06).
Conclusion: According to the results, it should be said that regular and periodic examination of the health level, and the promotion of educational and training programs on the subject of fasting to improve mental health, should be considered.

Majid Jangi, Azade Shayan Babokan, Nasim Ghalili Najafabadi, Sedigheh Torki Harchegani,
Volume 18, Issue 3 (7-2024)
Abstract

Background and Aim: Considering the limitation of resourses, improvement of the hospital efficiency is an absolute necessity. The Covid19 pandemic had a considerable effect on performance indicators of hospitals. This study aimed to investigate changes of indicators of hospitals affiliated to Isfahan University of Medical Sciences before and after Covid19.
Materials and Methods: This study was descriptive-cross sectional. The statistical population included all hospitals under the coverage of Isfahan University of Medical Sciences (38). The input data were related to the three years 2019 to 2021 (the year 2019 as the year before outbreak of Covid-19, the year 2020 as the first year of outbreak and the year 2021 as the second year of outbreak), which were collected using the researcher’s form based on reports extracted from the statistics and hospital information system available in the statistics and information technology management and finally the data analyzed through the PabonLasso model.
Results: Process of indicators during the years 2019-2021 shows that mean of indicators of bed occupancy rate and bed turnover rate as the first year of outbreak of Covid19 (2020) that was the peak of the disease has decreased as compared to the year 2019 and average length of stay has increased. In years 2019, 2020 and 2021, 24.32, 23.68 and 24.32 percent of hospitals were in the third area (efficient area). From 2019 to 2020, efficiency change was observed in 27 percent of the hospitals where 6 hospitals had positive trend and 4 hospitals had negative trend and from 2020 to 2021, efficiency change was observed in 16 percent of hospitals where 2 hospitals had positive and 4 had negative trend.
Conclusion: Considering the low efficiency of hospitals, it is suggested to carry out continuous and annual assessment of efficiency changes in hospitals in order to identify the causes of inefficiency early and preventing its drop and it is necessary for health managers and policy makers to take appropriate measures in the conditions of the outbreak of unexpected disease such as the outbreak of Covid-19 in order to use hospital resources more optimally.

Maliheh Javadi-Arjmand, Elia Damavandi, Hamid Choobineh, Majid Kabuli, Mohsen Ghadami,
Volume 18, Issue 3 (7-2024)
Abstract

Background and Aim: Follicle stimulating glycoprotein hormone (FSH) exerts its functions through its receptor (FSHR). In women of reproductive age, this hormone causes the growth and development of follicles in the ovary during the follicular phase of the menstrual cycle. This hormone is widely used in the treatment of infertility. Several polymorphisms have been reported so far in the FSHR gene, which are effective in the ovarian response, but the FSHR gene has two very common single nucleotide polymorphisms at positions 680 and 307 in exon 10. One of them at position 307 changes the amino acid threonine to alanine and the other at position 680 changes asparagine to serine. The polymorphism at position 307 of exon 10 is in the extracellular region of the receptor and the binding site of the hormone, which can be affected in response to internal and external FSH stimulation. These two SNPs have been reported to be associated with various ovarian responses and IVF outcomes in different populations. Different studies have particularly focused on rs6166 (p. Asn680Ser), but this study was conducted to investigate the possible association between rs6166 and rs6165 (p. Thr307Ala) and the IVF outcome.
Materials and Methods: After blood sampling and DNA extraction, the two polymorphisms in exon 10 of FSHR gene were analyzed using PCR-RFLP method in 120 women randomly assigned to two equal groups including IVF successful and IVF unsuccessful infertile women. The selection of patients to enter the study as well as the criteria for successful IVF are described in the text. In order to confirm the results, DNA sequencing was done for some selected samples. Finally, the results were analyzed using SPSS software.
Results: No significant differences were found in either SNPs between successful IVF and unsuccessful IVF patients in allelic frequencies (P-value>0.05).
Conclusion: Despite the different results of the studies conducted regarding the effect of FSHR gene polymorphisms (rs6165 and rs6166) in different populations, considering the lack of significant difference in the frequency of the above polymorphisms in the studied population, it is concluded that these two polymorphisms cannot be used to predict the outcome of IVF in Iranian infertile women.

Maryam Poormehdi, Nooshin Khandandezfully, Kumarss Amini,
Volume 18, Issue 3 (7-2024)
Abstract

Background and Aim: Thermophilic bacillus is a type of thermophilic bacillus, carries various genes and biosurfactants, microbial surfactants are surface active molecules produced by various microorganisms such as bacteria, yeasts and filamentous fungi. Biosurfactants are able to reduce the surface energy between phases and create electrostatic barriers, thus preventing the integration of particles. The aim of the present study was the molecular isolation of the srf  gene from thermophilic soil bacilli and its cloning in susceptible cells for industry use.
Materials and Methods: Fifteen samples from different regions of Kerman were collected and screened to isolate Bacillus strains. Morphological and biochemical studies were done to identify the strains. After biochemical examination of isolated microbial isolates and confirmation of Bacillus strains, DNA extraction was done. Then, the srf  gene was identified by PCR method from these isolates. The amplified fragment was inserted into pTG19 vector by TA cloning method. Then, the recombinant vector was transformed into E.coli origami bacteria and cloning was confirmed using common methods. The housekeeping gene 16S rRNA was used as the internal control of the test. The analysis of the gene expression level was performed by measuring the relative expression of mRNA as compared to the negative control that E.coli bacteria lacked the srf gene.
Results:  A total of 12 isolates of thermophilic bacilli were obtained from soil samples. As result, the PCR reaction for the srf  gene with the designed primers was found to be positive in 1 isolate (8.3%). The presence of srf  gene and the expression of this gene were checked by real time PCR test. Examining the white and blue colonies, M13 primer, junction location and determination of the 16S rRNA gene sequence confirmed the correctness of the cloning of the mentioned gene in the host bacteria.
Conclusion: As a result of the present study, it was possible to identify the native thermophilic bacillus carrying the srf gene, which can be used to obtain biosurfactant enzyme widely, conveniently and economically, for use in industrial and agricultural purposes, removing oil pollutants and reducing environmental surface tension, etc. which can be advantages.

Fahimeh Mohammadi, Maryam Shekofteh, Maryam Kazerani,
Volume 18, Issue 3 (7-2024)
Abstract

Background and Aim: The growth and development of scientific fields depends on correct and accurate planning and a general and comprehensive understanding of the structure of these fields. Scientific maps are a type of scientometric methods that help to understand the current state of scientific fields and reveal their internal structure. The aim of the present study is to analyze co-authorship and word co-occurrence maps of scientific publications of Iran in the field of endocrinology and metabolism.
Materials and Methods: This is a cross-sectional scientometrics study. The research population is all scientific publications of Iran in the field of Endocrinology and Metabolism on the Web of Science. The co-authorship and co-word maps were analyzed using VOSviewer, Gephi, and NodeXL software. Network analysis was done using social network analysis indicators. Thematic clusters and emerging subjects were also identified through the examination of word co-occurrence networks.
Results: The total scientific publications of Iran in the field of endocrinology and metabolism on the Web of Science was 4847 documents. The co-authorship network is a type of sparse network. The value of the cluster coefficient of this network was 0.212 and its diameter was 11. The average degree of the co-authorship network (6.62) shows that each node is connected with about 6 other nodes on average. The diameter of the co-authorship network is 11. The most productive and influential outhors are Azizi F and Larijani B. Six thematic clusters were identified in the word co-occurrence network, the largest one is oxidative stress and gene expression, followed by the obesity and diabetes cluster. The word “autoimmunity” is one of the emerging words in this field.
Conclusion: Iran’s research in the field of Endocrinology and Metabolism shows an increasing trend, but there is little cooperation between the authors of the field. Their co-authorship networks are sparse, and the authors’ tendency to form clusters is low. Therefore, planning is needed to increase scientific cooperation and the density of networks. It is suggested that the researchers of this field pay attention to the thematic clusters of the co-word network and emerging subjects in the design of their future research.

Somayyeh Zakerabasali, Farnaz Salehian,
Volume 18, Issue 3 (7-2024)
Abstract

Background and Aim: Today, information dashboards are the main tools for understanding and extracting knowledge from large data sets and can be used in various forms by healthcare providers. At the same time as the COVID-19 epidemic, several information dashboards were designed and developed. Still, due to the speed of the spread of this virus, there was no opportunity to evaluate them. Therefore, this research was conducted to evaluate the usability of the Covid-19 management dashboard.
Materials and Methods: This descriptive-cross-sectional study was conducted on the management dashboard of Shiraz University of Medical Sciences. The dashboard was evaluated using an exploratory evaluation method with the participation of three medical informatics experts. Each of the evaluators evaluated the system independently and identified its problems by using thirteen principle checklist. Then, with the presence of all evaluators, the list of identified problems was combined, repeated problems were removed from the list and a single list was prepared. In this joint meeting, any disagreements about the problems found by the evaluators were discussed and reached a common opinion. Finally, the evaluators determined and reported the severity of the problems.
Results: In this evaluation, a total of 79 usability problems were identified. The highest number of problems was related to the feature “Help and Documentation” (12 problems), and the lowest number of problems was related to the features “Aesthetic and Minimalist Design” (2 problems) and “Privacy” (1 problem). 45.58% of the identified problems were in the category of major problems. The average degree of severity of the problems was from 2.05 (minor problem) related to the feature of “Pleasurable and Respectful Interaction with the User” to 2.99 (major problem) related to the feature of “User Control and Freedom”. Also, the average severity of problems was calculated as 2.5, classified in the range of minor problems.
Conclusion: The heuristic evaluation method identifies user interface problems of information systems and dashboards using predetermined standards. If these problems are not resolved, they will cause users’ time wasted, errors to increase, information quality to decrease, and users’ dissatisfaction and confusion.

Fateme Hami Kargar, Narges Nikkhah Ghamsari, Mohammad Ganji,
Volume 18, Issue 4 (10-2024)
Abstract

Background and Aim: Breast cancer treatment is associated with changes in women’s bodies. Changes that are related to their femininity in addition to the appearance aspect and can face challenges in the part of women’s identity that is related to their body. This research deals with the process of changes in women’s physical identity in the context of culture and society
Materials and Methods: A qualitative method was used for the research, and in this regard, in-depth and semi-structured interviews were conducted with 15 women from Tehran who had undergone treatment for breast cancer, along with 5 companions who were alongside the patients during their illness, and 3 surgical doctors. The interviews focused on the experiences, emotions, and actions of the women in response to bodily changes. Sampling was conducted through purposive and snowball sampling methods. The thematic analysis technique developed by Braun and Clarke was employed for analyzing the interviews.
Results: The participating women were aged 27 to 65 years, with 8 holding bachelor’s degrees or higher. Seven women were housewives, 8 were employed, and 13 had undergone mastectomies. The main themes identified include changes in the female body, societal challenges, disruption of body image, support and companionship, economic constraints, and the redefinition of body image. These themes explain the process of women’s coping with bodily changes. Following bodily changes, women face challenges from society. Society judges women’s bodies after these changes and views them negatively. Furthermore, women experience dissatisfaction with their bodies, perceiving them as inadequate for fulfilling feminine roles and responsibilities as wives and mothers. However, over time, through acceptance of the changes and body management, women strive to reconstruct their body image. In addition, the women’s economic situation and the support and companionship of those around them—manifesting as acceptance of the bodily changes and emotional support—can facilitate the acceptance of these changes.
Conclusion: Given the importance of the body in defining femininity, women, after experiencing breast cancer, face not only the suffering of the disease but also identity challenges. Therefore, breast cancer treatment, alongside clinical interventions, requires societal awareness of how to interact with affected women.


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