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Showing 3 results for C-Reactive Protein

H Arazi, M Ebrahimi, K Hosseini,
Volume 4, Issue 3 (3-2011)
Abstract

Background and Aim: Prevalence of anabolic steroids (ASs) consumption among bodybuilders has increased progressively. Therefore, the purpose of this study was to evaluate the effect of ASs consumption on C-reactive protein (CRP) in bodybuilders.

Materials and Methods: Sixty healthy men (age: 24/1± 9/1yr weight: 77±10 kg and height: 172±12 cm) participated in the study voluntarily. These subjects were selected from three groups. First group (FG) was bodybuilders who consumed ASs (n=20), second group (SG) was bodybuilders who did not consume ASs (n=20) and third group (TG) were untrained subjects as control (n=20). Blood samples were collected in fasting state (12 hours) at 09:00 for CRP assessment. Strength and volume of the forearm, pectoral major and femur muscles were measured via 1RM test and muscle circumstances, respectively. Speed was assessed by 30m speed test. Analysis of variance test and LSD post-hoc test was used.

Results: FG had significantly greater blood CRP (P<0/05) compared to other groups. However, differences between SG and TG were not significant. Muscle strength, and forearm and femur circumstances were greater in FG than other groups. Furthermore, this was greater in SG than TG. But chest circumstance was greater in FG and SG than TG only. There were no significant differences in speed between groups.

Conclusion: ASs consumption for muscle strength and volume improvement in bodybuilders is accompanied by higher level of CRP (as a cardiovascular risk factor).


Shahla Alikhani, Zaher Etemad, Kamal Azizbeigi,
Volume 15, Issue 3 (8-2021)
Abstract

Background and Aim: Sedentary life style increases risk of cardiovascular diseases (CVDs). Physical activity and green tea supplementation can reduce cardiovascular risk factors by improving inflammation and body composition. The aim of study was to determine benefits of 8 weeks of spinning training and green tea supplementation on risk factors cardiovascular and body composition in overweight women.
Materials and Methods: A total 32 overweight women based on BMI (Body Mass Index) (27.1±1.6) and (24.9±3.6 years) were randomly divided into three groups: Spinning+green tea (n=11), spinning+placebo (n=11) and control (placebo +no training) (n=10). Training groups carried out 8 weeks of spinning training with an intensity of 11-17 Rating of Perceived Exertion (RPE). Blood sampling were obtained 48 h before starting the interventions and then 48 h after last training session. Serum concentration of hs-CRP (high sensitive C-reactive protein) and blood level of fibrinogen were measured. In addition, BMI and BF% (Body fat percent), bioelectrical impedance analysis was performed.
Results: After 8 weeks of interventions only hs-CRP was significantly decreased in spinning+green tea group (P=0.005). In addition, fibrinogen (P=0.001), BF% (P=0.001) and BMI (P=0.001) were significantly decreased in both training groups. Also, there was significant difference of hs-CRP in the training groups (P=0.028). However, no significant difference of fibrinogen and BF% were observed between the training groups. In the case of fibrinogen both spinning+green and spinning+placebo groups had a significant difference with control group (P=0.004), (P=0.014) respectively. Regarding BF% and BMI only a significant difference wera between the spinning+green and control (P=0.006), (P=0.007) respectively.
Conclusion: It seems that spinning training has improved risk factors of cardiovascular and body composition. Indeed, green tea supplementation has increased the effectiveness of spinning training.


Mr Ali Asghar Shariati Aghamahalli, Masoumeh Habibian,
Volume 15, Issue 3 (8-2021)
Abstract

Background and Aim: Low-grade systemic inflammation, sedentary lifestyle, and vitamin D deficiency are considered risk factors for developing non-specific low back pain. The aim of this study was to investigate the effect of selective lumbar stabilization exercises with vitamin D intake on the level of hypersensitive C-reactive protein (hs-CRP) and 25-hydroxy vitamin D levels in women with chronic non-specific low back pain.
Materials and Methods: In this semi-experimental study with pretest–posttest design, 48 women with chronic low back pain were initially selected by available sampling method and then randomly divided into control, exercise, vitamin D and combined groups. Lumbar stabilization exercises were performed at different levels for 8 weeks. The vitamin D and combined groups received 50,000 IU vitamin D weekly. Data were analyzed using paired t-test, ANOVA and Kruskal-Wallis tests with a significant level of less than 0.05. 
Results: 25.64% and 74.26% of the subjects had insufficient levels of vitamin D (20-29 ng/ml) and vitamin D deficiency (less than 20 ng/ml), respectively. 8 weeks of lumbar stabilization exercises, vitamin D consumption, and the combined intervention decreased hs-CRP and increased 25-hydroxyvitamin D. In addition, the combined intervention had a stronger effect on lowering hs-CRP levels compared to the other two interventions. The effect of vitamin D intake and combined intervention on improving vitamin D status was greater compared to lumbar stabilization exercises.
Conclusion: It seems that lumbar stabilization exercises, vitamin D intake, and combined interventions can improve low-grade systemic inflammation in people with low back pain and low vitamin D levels by lowering hs-CRP and positively regulating 25-hydroxyvitamin D, but combined intervention is associated with greater effectiveness in reducing hs-CRP.


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