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Association between Iron, TIBC and Ferritin with Thyroid Hormones Levels in Patients Referred to Shouride Clinic Laboratory
Roya Sehat, Esmaeil Shahabi Satlsar, Parichehr Hanachi,
Volume 13, Issue 2 (7-2019)
Abstract
Background and Aim: Iron deficiency is one of the most common nutritional disorders in the world, and it may affect the metabolism and function of a number of proteins, including the level of thyroid hormones. As such, fluctuations in the level of thyroid hormones may also affect the body's iron status. The present study aimed to evaluate the relationship between thyroid hormones and the status of iron stores.
Materials and Methods: The study populations included referral patients to laboratory of Shourideh clinic in Mashhad, Iran. Fe, Ferritin, TIBC (total iron-binding capacity), TSH, T4, T3, and CRP tests were performed with a physician's request. The target sample size was a total of 420 patients including 287 women and 133 men with an average age of 41.5 years. TSH and Ferritin test were measured by Elisa method, Fe and TIBC were measured by automated method.
Results: The results showed no significant relationship between the body's iron status and thyroid hormones level (P˃0.05). Interestingly, in subjects with lower iron level, TSH was at the highest level and T4 was at the lowest level. However, no positive relationship was found between iron status and T3 level.
Conclusion: Although, there was no significant relationship between iron status and thyroid hormones level in the present study, it seems that the fluctuations of each of them may affect somehow the other.

The Effect of Eight Weeks Aerobic Training on Serum Ferritin Level, Glycemic and Lipid Indices in Women with Type 2 Diabetes
Atefeh Helmi Siyasi, Nahid Bijeh, Elham Hakak Dokht, Gholam Rasul Mohammad Rahimi,
Volume 15, Issue 2 (5-2021)
Abstract
Background and Aim: Recent studies indicate that increased body iron stores have been associated with the development of glucose intolerance and type 2 Diabetes. Ferritin is the most important iron storage protein in the body, which is used to evaluate disorders associated with iron metabolism. The aim of this study was to examine the effect of eight weeks of aerobic training on serum ferritin level, glycemic and lipid indices in women with type 2 Diabetes.
Material and Methods: Twenty Diabetic women aged 45-55 years were selected voluntarily and divided into experimental (n=10) and control (n=10) groups. The experimental group participated in the aerobic training program for eight weeks, three 60-minutes sessions per week with an intensity of 55-65% of heart rate reserve. The control group did not participate in any activity during the intervention period. Serum ferritin, glycemic and lipid indices were evaluated before and after eight weeks and then data were analyzed by SPSS software.
Results: Ferritin (P=0.012), insulin (P=0.004), fasting glucose (P=0.041), insulin resistance index (P=0.012), total cholesterol (P=0.041), and triglyceride (P=0.005) significantly decreased, while the mean of HDL(P=0.012) significantly increased in the experimental group. Moreover, the results showed that changes in ferritin (P=0.002), insulin (P=0.014), insulin resistance index (P=0.001) and TG (P=0.010) were statistically significant between the experimental and control groups.
Conclusion: Women with type 2 Diabetes can benefit from moderate-intensity aerobic exercise programs to improve their glycemic and lipid profile, as well as iron metabolism abnormalities.

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