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Showing 3 results for Fibrinogen
Response of Lipoprotein a, Blood Coagulation and Fibrinolysis Factors to Aerobic Exercise in Overweight Women
Roghayeh Shad, Nahid Bijeh, Mehrdad Fathi,
Volume 12, Issue 6 (3-2019)
Abstract
Background and Aim: Despite the significant progress in the field of health, Cardiovascular diseases are the leading cause of death among people. For this purpose, the present study was conducted to evaluate the effect of eight weeks of aerobic exercise on lipoprotein a, blood coagulation and fibrinolysis factors in overweight women.
Materials and Methods: In this semi experimental study with pre and post-test design, 21 overweight women subjects aged between 20 and 30 were randomly selected from experimental (10 people) and control (11 people). The aerobic exercise protocol consisted of five sessions per week for 30 minutes and with an intensity of 55%-75% heart rate reserve (HRR). Blood samples were collected from subjects in two stages to evaluate the considered variables. Measurement of levels of Lipoprotein a, Fibrinogen, PT, PTT, Platelet counts and Hemoglobin. For data analysis, repeated measures of variance analysis at a significant level of 5 hundredths were used by employing SPSS software.
Results: The mean values of Lipoprotein a, Fibrinogen, PT and Platelet counts in the control group showed no significant change after eight weeks of training (P>0.05). While PTT changes in the both groups was significant in the post-test compared to the pre-test (P=0.006). The inter-group difference, in any of the variables between the experimental and control groups, was not significant (P>0.05).
Conclusion: Eight weeks of aerobic training had no effect on Lipoprotein a and blood coagulation and fibrinolysis factors, however, this training program can take effective steps in improving health promotion in overweight women.

The Effect of Eight Weeks of Aerobic Training on Serum Lipid Profile and Serum Level of Fibrinogen in Middle-Aged Men with Heart Failure
Malihe Shamsizadeh, Seyed Mahmood Hejazi, Shima Minaee, Hoda Haghir, Laaya Rajayi,
Volume 14, Issue 1 (3-2020)
Abstract
Backgrounds and Aim: Cardiovascular diseases, especially atherosclerosis, are among the main causes of mortality in developing countries of Asia and West Asia. The purpose of this study was to investigate the effect of eight weeks of aerobic training on serum lipid profile and fibrinogen in middle-aged men with heart failure.
Materials and Methods: Twenty men with aged 50 to 60 years, with heart failure grade 1 to 3, and heart power of less than 45% were selected and then randomly divided into experimental and control groups. Aerobic exercise was included of eight weeks of aerobic training with intensity of 35-65% of maximal heart rate with a three-session frequency per week. Fasting blood samples were collected from participants before and after of eight weeks. Data were analyzed by Paired sample t-test and Independent sample t-test.
Results: The results showed that after eight weeks of intervention, mean changes of HDL, TC / HDL ratio and fibrinogen were statistically significant (P<0.05). On the other hand, mean changes in LDL, TG, TC and LDL / HDL ratio were not significant (P>0.05).
Conclusion: The results of this study indicate that performing aerobic exercises along with drug therapy can be useful as a good way to prevent cardiovascular disease in people with heart failure

Benefits of Spinning Training and Green Tea on Risk Factors of Cardiovascular in Overweight Women
Shahla Alikhani, Zaher Etemad, Kamal Azizbeigi,
Volume 15, Issue 3 (8-2021)
Abstract
Background and Aim: Sedentary life style increases risk of cardiovascular diseases (CVDs). Physical activity and green tea supplementation can reduce cardiovascular risk factors by improving inflammation and body composition. The aim of study was to determine benefits of 8 weeks of spinning training and green tea supplementation on risk factors cardiovascular and body composition in overweight women.
Materials and Methods: A total 32 overweight women based on BMI (Body Mass Index) (27.1±1.6) and (24.9±3.6 years) were randomly divided into three groups: Spinning+green tea (n=11), spinning+placebo (n=11) and control (placebo +no training) (n=10). Training groups carried out 8 weeks of spinning training with an intensity of 11-17 Rating of Perceived Exertion (RPE). Blood sampling were obtained 48 h before starting the interventions and then 48 h after last training session. Serum concentration of hs-CRP (high sensitive C-reactive protein) and blood level of fibrinogen were measured. In addition, BMI and BF% (Body fat percent), bioelectrical impedance analysis was performed.
Results: After 8 weeks of interventions only hs-CRP was significantly decreased in spinning+green tea group (P=0.005). In addition, fibrinogen (P=0.001), BF% (P=0.001) and BMI (P=0.001) were significantly decreased in both training groups. Also, there was significant difference of hs-CRP in the training groups (P=0.028). However, no significant difference of fibrinogen and BF% were observed between the training groups. In the case of fibrinogen both spinning+green and spinning+placebo groups had a significant difference with control group (P=0.004), (P=0.014) respectively. Regarding BF% and BMI only a significant difference wera between the spinning+green and control (P=0.006), (P=0.007) respectively.
Conclusion: It seems that spinning training has improved risk factors of cardiovascular and body composition. Indeed, green tea supplementation has increased the effectiveness of spinning training.

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