Background and Aim: Given the high sensitivity of the medical field, a mistake can cause irreparable damage to human society. For this reason, finding the symptoms of the disease and the relationships between them to facilitate the improvement of diseases is inevitable. Therefore, the aim of the present study was to first identify the symptoms of neurofibromatosis type 1 by specialists, then determine the relationship between the symptoms and the degree of their impact on each other in order to determine the most important criterion in improving the disease.
Materials and Methods: The present study is of a developmental-applied type in terms of its purpose and of a descriptive-survey type in terms of its data collection method. The case study of the present study is spinal disorders, of which neurofibromatosis type 1 has been diagnosed as one of them based on the opinion of experts. Neurofibromatosis type 1 is a genetic disorder that causes tumors in the nervous tissue. Accordingly, in the present study, the criteria, which are the symptoms of the disease, were first determined using the opinion of a group of experts and the implementation of the fuzzy Delphi method. In the next step, a model for the causal relationships between the symptoms of the disease is presented. For this purpose, a fuzzy cognitive map is drawn using MATLAB, FCMapper and Pajek software, then backward and forward scenarios are presented for neurofibromatosis type 1 and the disease improvement scenario is determined.
Results: The results showed that hormonal changes, flat brown spots on the skin, freckles in the armpit and groin area, soft bumps on the face or under the skin, high blood pressure, respiratory problems, bumps on the iris of the eye (Lish nodules), tumor in the optic nerve-ocular glioma, short stature, bone deformity, learning disabilities-attention deficit hyperactivity disorder (ADHD) and larger than average head size are ranked first to twelfth, respectively. The causal relationships between the symptoms showed that the criterion of hormonal changes has the greatest impact on the criterion of freckles in the armpit or groin area; Therefore, if the hormonal changes criterion improves, neurofibromatosis type 1 will also improve.
Conclusion: The findings of this study have helped the medical community to have a better understanding of the symptoms of the disease so that doctors can improve their prevention and care recommendations based on the severity of the symptoms of the diseases.
