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Showing 2 results for Multiple Sclerosis

Reza Safdari, Abdorreza Naser Moghadasi, Sahar Khenarinezhad, Ehsan Ghazanfarisavadkoohi,
Volume 14, Issue 5 (1-2021)
Abstract

Background and Aim: Taking a wide range of medications in Multiple sclerosis (MS) patients can lead to side effects and drug interactions. Therefore, the use of intelligent systems such as drug monitoring systems can help in the effective and timely treatment of MS disease. In this regard, the present study was conducted to design, development, and evaluation of the drug monitoring system for multiple sclerosis patients.
Materials and Methods: The present descriptive-developmental study was performed in four stages. In the first stage, by searching the library resources and valid guidelines, the minimum data set was determined and provided to neurologists and MS fellowships in the form of checklists for validation. Then the software was designed logically and coded based on the opinion of experts. In the last stage, the software was evaluated by end-users.
Results: The information elements in the software design were categorized into patient demographic information, medical history, clinical signs, imaging procedures, laboratory tests for ocrelizumab and fingolimod drugs, counseling, and treatment data. Finally, the performance of the drug monitoring system was evaluated with an average of 7.9 and was approved by users.
Conclusion: The results of software evaluation showed that the drug monitoring system can help general practitioners, neurologists, and MS fellowships in monitoring and follow-up of patients and lead to increased patient safety.

Elahe Behmani, Rastegar Hoseini, Ehsan Amiri,
Volume 14, Issue 6 (1-2021)
Abstract

Background and Aim: Multiple sclerosis (MS) is a progressive disease of the central nervous system, of which the symptoms and problems reduce the quality of life. Recent research has identified sport exercises as an important part of healthy lifestyle in reducing the symptoms of the disease and improving the quality of life; however, the most effective type of exercise is not yet clearly known. The aim of this study was to provide information about the beneficial effects of exercise in MS patients and guidelines for prescribing exercise programs for them.
Materials and Methods: This article is an overview of the ways different sport exercises affect MS. To access scientific articles, databases of PubMed, SID, Google Scholar, and Mag Iran, and the keywords including multiple sclerosis (MS), aerobic training, resistance training, and combined training were used.
Results: Recent reports show that different types of sport exercises lead to a significant increase in the improvement of MS symptoms, although there are many discrepancies between researchers in prescribing different exercise programs (various training protocol, duration, and intensity). However, according to the results of studies, regular moderate-intensity exercise training leads to the functional benefits and improvement and control of the disease process without exacerbation of inflammation through various physiological mechanisms. thus, contrary to popular belief, modulated exercise training can have beneficial effects on MS patient.

Conclusion: Based on the findings of the present study, regular exercises (aerobic, resistance and combination) with moderate intensity improve the symptoms of MS and increase the quality of life.


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