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Dosing of Warfarin in Iranian Adult Patients with An Artificial Heart Valve Using Artificial Neural Networks
Azam Orooji , Mostafa Langarizadeh , Maryam Aghazadeh, Mehran Kamkarhaghighi, Marjan Ghazisaiedi , Fateme Moghbeli,
Volume 12, Issue 4 (11-2018)
Abstract 
Background and Aim: Artificial intelligence is a branch of computer science that has the ability of analyzing complex medical data. Using artificial intelligence is common in diagnosing, treating and taking care of patients. Warfarin is one of the most commonly prescribed oral anticoagulants. Determining the exact dose of warfarin needed for patients is one of the major challenges in the health system, which has attracted the attention of researchers. The purpose of this study was to determine the exact dose of warfarin needed for patients with artificial heart valves using artificial neural networks (ANN).
Materials and Methods: A total of 9 multi-layer perceptron ANNs with different structures were constructed and evaluated based on a dataset including 846 patients who had referred to the PT clinic in Tehran Heart Center in the second half of the year 2013. Finally, the best structure of ANN for warfarin dose was investigated. All simulations including data preprocessing and neural network designing were done in MATLAB environment.
Results: The effectiveness of ANNs was evaluated in terms of classification performance using 10-fold cross-validation procedure and the results showed that the best model was a network that had 7 neurons in its hidden layer with an average absolute error of 0.1, turbulence rate of 0.33, and regression of 0.87. 
Conclusion: The achieved results reveal that ANNs are able to predict warfarin dose in Iranian patients with an artificial heart valve. Although no system can be guaranteed to achieve 100% accuracy, they can be effective in reducing medical errors.

Comparison of Data Mining Algorithms' Efficiency in Thyroid Disease Diagnosis
Mohsen Rezaei, Nazanin Zahra Jafari, Hossein Ghaffarian, Masoud Khosravi Farmad3, Iman Zabbah, Parvaneh Dehghan,
Volume 13, Issue 5 (1-2020)
Abstract
Background and Aim: Timely diagnosis and treatment of abnormal thyroid function can reduce the mortality associated with this disease. However, lack of timely diagnosis will have irreversible complications for the patient. Using data mining techniques, the aim of this study is to determine the status of the thyroid gland in terms of normality, hyperthyroidism or hypothyroidism.
Materials and Methods: Using supervised and unsupervised methods after data preprocessing, predictive modeling was performed to classify thyroid disease. This is an analytical study and its dataset contains 215 independent records based on 5 continuous features retrieved from the UCI machine learning data reference.
Results: In supervised method, multilayer perception(MLP), learning vector quantization(LVQ), and fuzzy neural network(FNN) were used; and in unsupervised method, fuzzy clustering was employed. Besides, these precision figures(0.055, 0.274, 0.012 and 1.031) were obtained by root mean square error(RMSE) method, respectively.
Conclusion: Reducing the diagnosis error of thyroid disease was one of the goals of researchers. Using data mining techniques can help reduce this error. In this study, thyroid disease was diagnosed by different pattern recognition methods. The results show that the fuzzy neural network(FNN) has the least error rate and the highest accuracy.

Automatic Spelling Correction in Persian Sonography Text with Neural Networks
Seyed Mohammad Sadegh Dashti, Amid Khatibi Bardsiri, Mehdi Jafari Shahbazzadeh,
Volume 18, Issue 1 (3-2024)
Abstract
Background and Aim: Medical reports and electronic health records are critically important for diagnosis, treatment, patient protection, and medical research. Correcting spelling errors in medical texts is essential to ensure accurate interpretation of information. This research was conducted to automatically correct spelling mistakes in Persian medical texts using neural networks.
Material and Methods: In this study, which was conducted in 2023, a computational model based on artificial intelligence neural networks and dual embedding techniques was developed using Python in a Windows environment. The dual embedding model was fine-tuned for correcting spelling errors in Persian sonography texts. The proposed model employs various techniques for automatic error detection, including dictionary lookup approach and contextual similarity coefficients. Furthermore, features specific to text processing, such as Edit-Distance, along with similarity coefficients, were utilized to automatically select the most appropriate substitute for a misspelled word. The training and testing data for the current model were sourced from a collection of sonography texts from the Imam Khomeini Hospital’s sonography clinic in Tehran.
Results: The proposed model which is based on artificial neural networks, leverages a novel dualembedding architecture to select the best candidate words for correcting both non-word and real-word errors. According to the evaluation results on Persian sonography text, the proposed model achieved an F-Measure accuracy of 90.5% in detecting real-word errors. Furthermore, it demonstrated an impressive 90% accuracy in automatically correcting these real-word errors. Additionally, the model exhibited a strong performance, achieving 90.8% accuracy in correcting non-word errors.
Conclusion: Based on the evaluation results, the proposed method is robust against various changes in word forms and can effectively manage a wide range of morphological and semantic errors, including replacements, transpositions, insertions, and deletions in medical texts. The integration of EditDistance with textual similarity coefficients extracted from the dual embedding model significantly enhanced the accuracy of spelling corrections in Persian sonography texts, ensuring greater validity of such documents. The authors believe that the proposed model represents a significant advancement in the detection and correction of spelling errors in Persian sonography texts.

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