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Showing 7 results for Obesity
The Study of prevalence of Hypercholesterolemia and some relative factors in Golestan province
Ghr Veghari, Hr Joshaghani, Sa Hoseini, Sm Sedaghat, F Nik Nezhad, Ah Angizeh, E Tazik, P Maharloei,
Volume 3, Issue 3 (3-2010)
Abstract

Background and Aim: Cardiovascular disease is the first and for most factor for mortality in adults and hypercholesterolemia (HC) is a susceptible agent for them. The main objective of this study is to determine the of prevalence of HC and some risk factors related to it in adults in Golestan province  in 2006.

Materials and Methods: This is a Crossectional-Descriptive study based on population and 1995 cases (997 men and 998 woman) between 25- 65 years old, were chosen by cluster and stratify sampling in Golestan adult population. We interviewed all the cases and determined anthropometric and biochemical indexes. Data was analyzed by SPSS.14 software. HC was defined as serum cholesterol levels over 200 mg/dl.

Results: Mean age was 39.2 year and mean ±SD of serum cholesterol in men and women was 196.7±39.11 and 209.4± 42.9 respectively. Prevalence of HC showed significant deference between men (44.7%) and women (57%) (P<0.05). There is a  significant difference between age groups, region, physical activity and BMI in the mean value of serum cholesterol (P<0.01) but regarding economic status it is not significant. Prevalence of HC in abdominal obese and healthy group is 63.2% and 41% respectively and statistical difference is significant (P<0.05). The people of Golestan province consume fruits , vegetables and fish 4.84, 3.65 and 2 days in a week  respectively and  vegetable and fish are consumed more in HC group than in non- HC group. The consumption of hydrogenated oil, liquid oil and other type of oils is 85.4% ,14% and 0.7% respectively, and in HC people the intake of liquid oil is slightly higher than others, but statistical differences is not significant.  

Conclusions: HC is one of the most health problems in Golestan province and women suffer from it more then men. Life style and food behavior are two risk factors for it. Thereby correction of food and social behavior can decline incidence of cardiovascular disease.


The Prevalence Of Obesity In Primary Schools Of Golestan Province Of Iran
Gholam Reza Veghari, Reza Rahmati,
Volume 5, Issue 4 (1-2012)
Abstract

Background and Aim: Underlying factors of Obesity is various and the main aim of this study was to evaluate the prevalence of obesity and some socio-demographic related factors among Iranian northern primary school children in year 2010.

Materials and Methods: This is a crossectional-descriptive study that was performed on 7399 primary school children (3934= male and 3465=female) from 112 schools that were chosen by two step sampling (cluster and simple random). The number schools were equal with respect to residential area and sex. Center of Disease Control and prevention (CDC) criteria was used for comparing anthropometric indexes.

Results: Linear regression analysis revealed that weight, height and BMI increase 2.70 kg, 4.62 cm and 0.42 kgm-2 in boys (P=0.001) and 3.12 kg, 5.19 cm and 0.52 kgm-2 in girls (P=0.001) in each of years, respectively. Highest and lowest obesity was observed in Gomishan and Ramian districts, respectively. Results of logistic regression analyses showed that the risk of overweight and obesity was 1.203 times in male as compared to females[1.078-1.341, CI 95%], 1.382 times in urban as compare to rural areas[1.240-1.541, CI 95%] and 2.297 times in high economic group as compared to low economic group[1.911-2.761, CI 95].

Conclusion: Obesity was a health problem in primary school children in Golestan province and urbanization and rise of economic status was a risk factor.


Obesity Among Female Adolescents Of Tehran Schools 
Masumeh Shakeri, Yusef Mojtahedi, Javad Naserian, Maryam Moradkhani,
Volume 6, Issue 5 (1-2013)
Abstract

Background and Aim: Obesity in childhood can cause obesity and its related complications in adulthood. This study was aimed to determine the correlateion between obesity among female adolescents and its related complications of Tehran schools in 2011.

Materials and Methods: In this cross-sectional study, 810 female adolescents, aged 12-16 years old, studying in schools of Tehran University of Medical Sciences were selected using multi-stage random sampling. Height and weight of the participants were measured and their BMI calculated. Data were collected using a questionnaire. Validity and reliability of the questionnaire was confirmed using content validity and test-retest. Using BMI, the participants were categorized into obese(BMI>95 percentile for age and gender) and overweight(BMI between 85 and 95 percentiles for age and gender) individuals. Data were analyzed using the Chi-squared test, Fisher's exact test, ANOVA, and multivariate logistic analysis.

Results: The prevalence of overweight and obesity in our study were 4.4%(95% CI 4/2-6/4) and 14/1%(95% CI 10/25-15/3), respectively. There was a statistically significant relationship between obesity and TV watching(p<0.001).

Conclusion: Based on our findings, further investigations are recommended to determine factors affecting overweight.


Investigation Of Adiponectin To Leptin Ratio, Insulin Resistance And Pulmonary Function Profile In Obese Chronic Asthmatic Males
Farzad Nazem, Behzad Keshavarz,
Volume 7, Issue 2 (7-2013)
Abstract

Background and Aim: Plasma leptin, adiponectin (as theadipokines) and related obesity – HOMA index in the obese men are introduced as a predictive metabolic indicators for asthmatic individuals. However, under asthma conditions, role of cariometabolic variables interaction for altering clinical pulmonary indexes aren't clear. In the present study, the relationship between plasmatic adiponectin to leptin ratio (adipo/lep) with respiratory capacities & HOMA in the chronic asthmatic males are investigated.

Materials and Methods: Thirty nine obese males with mild to moderate asthma with an average age of 38±2.6 ys and BMI 31.4 ± 1.06 kg/m2 voluntarly participated in this study. Baseline plasmatic leptin, adiponetin, insulin and glucose levels were determined after 10-12 hours fasting overnight. FEV1/FVC, PEF% and FEF 25%-75% were determined by standard method. A pearson correlation test was used to analyse data.

Results: There were no significant correlation between WHR , BMI with metabolic risk factors (P>0.05). Relationship markedly observed among HOMA with adipo/ lep ratio and leptin levels respectively (P<0.05), Also a marked negative correlation between adipokine ratio and leptin level was obtained (P<0.05). From view of respiratory efficiency, FVC% and FEV1/ FVC were maingly corrected with baseline leptin&adiponectin levels (P<0.05).

Conclusion: Inconclusion,it seems that adipo/lep ratio biomarker plays as a clinical diagnosis index for HOMA index than baseline leptin or adiponectin levels. However, these findings showed that FEV1/FVC & adipo/lept ratios are accounted as valuable indicators for evaluating the obesity syndrome and pulmonary efficiency in the asthma disease.


The Role Of Eating Attitude On Obesity-Related Eating Behavior In Overweight And Obese Women Of Urmia In 2012
Maryam Mataji Amirrood , Mohammad Hosein Taghdisi, Mahmood Reza Gohari, Farzad Shidfar,
Volume 8, Issue 6 (3-2015)
Abstract

Background and Aim: Identifying obesity-related eating behavior predictors especially in women, who have a key role in their family's food basket, has a great importance in the prevention of obesity. The purpose of the present study is to determine the role of eating attitude on obesity-related eating behavior in overweight and obese women in Urmia.

Materials and Methods: The present descriptive-analytical study was performed on 100 overweight or obese women covered by Shahid Nikkhah and No. 13 Health Centers in Urmia. Sampling was conducted through c onvenience method and women with a BMI equal to or more than 25 (kg/m2) were selected. Following their informed consent, they completed the questionnaires about demographic characteristics , attitude, and food behavior checklist. Data analysis was conducted using SPSS software version 18 and descriptive and inferential statistics (Chi-square , analysis of variance and regression ) at 0.05 significance level .

Results: The result confirmed that there was a significant relationship between attitude and poor , average and good eating behavior groups of women (p=0.003).

  Regression analysis revealed a positive and significant relationship between eating behavior and attitude scores (p=0.004, r=0.285) . Also, prediction of observed distribution in eating behavior was confirmed by age , anthropometric indices and demographic factors in addition to eating attitude .

Conclusion: The study results confirmed the predictive role of eating attitude on obesity-related eating behavior. Therefore, it is recommended that correction of eating attitude be emphasized in the promotion of healthy eating behavior.


FAS and ACC dysfunction in visceral Adipose Tissue
Ehsan Khalili, Naghmeh Janat Alipour, Reza Meshkani, Karamolah Tolabi, Solaleh Emamgholipour,
Volume 14, Issue 2 (5-2020)
Abstract
Background and Aim: A great interest for determining the particular mechanisms underlying lipogenesis and adipogenesis has been raised among researchers in order to fight obesity. We aimed to investigate the gene expression of FAS and its role in regulation of lipogenesis and adipogenesis in visceral adipose tissues from obese and normal-weight subjects.
materials and Methods: A total of.participants including 40 obese patients(BMI≥35 kg/m2 according to WHO criteria) and 20 healthy subjects(BMI=18.8-24.9 kg/m2 according to WHO criteria) were recruited from who were referred to Erfan, Loghman Hakim, Sina, and Imam Khomeini hospitals bypass or sleeve gastrectomy surgeries in obese ones and elective surgery in controls. Participants were all woman aged from 20-50 years and postmenopausal subjects were not included in this study. Isolated total RNA from adipose tissue was used to synthesize complementary DNA(cDNA) and quantitative real-time PCR was performed for analyzing the gene expression of FAS, and ACC. Data was normalized to geometric means of GAPDH and β-actin expression levels.
Results: in VAT from obese subjects, gene expression of FAS was higher than in those from controls. We found a positive correlation between genes expression of FAS and ACC with obesity indices.
Conclusion: It appears that obesity is associated with dysregulation of FAS genes involved in lipogenesis and adpogenesis.

The Association of Dietary Insulin Index and Load with Resting Metabolic Rate (RMR) in Women Referred to Health Centers of Tehran University of Medical Sciences
Hossein Hassani, Maryam Arab-Moorchegani, Narges Parsaie, Mahshid Rezaei, Khadijeh Mirzaei, Hossein Imani, Mir Saeed Yekaninejad,
Volume 16, Issue 2 (5-2022)
Abstract
Background and Aim: Currently, utilizing different nutritional indicators to investigate the association between diet and various diseases is considered in previous studies, which is related with some chronic diseases. However, no studies have studied the connection between the indicators with the rate of metabolism at rest (RMR). Therefore, the present study aimed to determine the relationship between dietary index and insulin load with resting metabolic rate (RMR) in overweight and obese women
Materials and Methods: A total of 280 healthy overweight and obese women (aged 18-50 years) who were referred to community health centers of Tehran University of medical sciences were included. In this study anthropometrics measurements such as weight, height, waist circumference, waist to hip ratio, body mass index, fat percentage, and fat-free mass were evaluated for every participant. Data on dietary intakes were collected using 147 semi-quantitative food frequency questionnaire (FFQ). DII and DIL were calculated using food insulin index values published earlier. To assess the RMR, indirect calorimetry was used. 
Results: Mean age of study participants was 36.4±8.38 years. Although a significant association was seen between DII and RMR in a crude model (P=0.04); adjusting for different confounders made this significant relationship between DII and RMR insignificant. In addition, the dietary insulin index had no significant relationship with the amount of RMR/kg (p=0.63) and RMR/FFM (p=0.73).
Conclusions: Based on the results of this cross-sectional study, it seems that the insulin index and insulin load of the diet are not associated to the rate of resting metabolism. However, due to the limitations of this study, findings can only confirm or reject the hypothesis under further studies. It is also necessary to determine the role of dietary insulin indicators on human health, especially with a Study Prospective Design

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