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1392/1/25، جلد ۴۳، شماره ۱، صفحات -
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
DETERMINATION OF SALIVARY CORTISOL IN HEALTHY CHILDREN AND ADOLESCENTS |
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| چکیده انگلیسی مقاله |
Recognized as a reliable tool for assessing the hypothalamus-pituitary-adrenal (HPA) axis, measurement of salivary cortisol plays an important role in both the clinical and research settings. To establish a normative data, which forms the basis for the usage of this valuable parameter, we gathered 8:00 h saliva samples from 94 healthy individuals aged 6-14 years. Cortisol levels were measured by radioimmunoassay technique, using Orion Diagnostica's coated tube technology. Based on mean±2SD, we established a normal range for salivary cortisol concentrations in this age group: 1.69 - 12.81nmol/L. Considering a confidence interval for upper and lower limits, there was an upper limit equal to 11.42 -14.29 nmol/L and a lower limit of 1.21 - 2.25 nmol/L. Regarding the results of this study, cortisol levels were age dependent, and although with a low correlation coefficient, there was a positive correlation between cortisol levels and weight and height. There was no correlation with BMI and no sex difference was found. |
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| کلیدواژه‌های انگلیسی مقاله |
"Salivary cortisol, normal range, adolescents, hypothalamus-pituitary-adrenal axis", |
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| نویسندگان مقاله |
36219---36220---36221--- |
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| نشانی اینترنتی |
http://acta.tums.ac.ir/index.php/acta/article/viewArticle/2807 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Article(s) |
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