|
|
1393/7/27، جلد ۵۲، شماره ۱۰، صفحات -
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژههای فارسی مقاله |
|
|
| عنوان انگلیسی |
Evaluation of the Expression of P-Glycoprotein in Propoxur-Resistant Caco-2 Cells |
|
| چکیده انگلیسی مقاله |
There is a great concern about the effect of propoxur, as one of the more common N-methyl carbamate pesticides, on human health due to its extensive use in agricultural and non-agricultural applications. Caco-2 cells became resistant to propoxur, and the resistance was confirmed through MTT assay. Then the cell membrane integrity and P-glycoprotein expression were measured by LDH assay and western blot analysis, respectively and compared to the parent cells. Contrary to what was expected, the expression of P-glycoprotein in propoxur resistant cells was lower than parent cells. Conclusion: This study indicates that the resistance to propoxur may not be related to P-glycoprotein expression directly, since P-glycoprotein expression has decreased in these cells. |
|
| کلیدواژههای انگلیسی مقاله |
Propoxur; Toxicity; P-glycoprotein; Resistant |
|
| نویسندگان مقاله |
38419---38420---38421---38422---38423---38424---38425--- |
|
| نشانی اینترنتی |
http://acta.tums.ac.ir/index.php/acta/article/viewArticle/5050 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
|
| نوع مقاله منتشر شده |
Original Article(s) |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|
