1391/7/29، جلد ۳۷، شماره ۲، صفحات -

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عنوان انگلیسی EVALUATION OF T LYMPHOCYTE SUBSETS IN CHILDREN WITH BETA THALASSEMIA MAJOR
چکیده انگلیسی مقاله Peripheral blood T lymphocytes and their subsets were studied in 31 patients with beta thalassemia major (age 2-12years) and compared with 14 age-arid sex-matched healthy controls. Three monoclonal antibodies (anti-CD3, anti CD-f, unti-CDS) were simultaneously applied for detection of Th (CD3-, CD4^), Tsk (CD3+, CD8+) and Th/Ts ratio by flow-cytometry respectively. The results of this study showed a slight increase in the number of Tlymphocytes, T 004^, TCDS+, and CD4'*/CDS* ratio; but this increase was not statistically significant (P>0.05). No primary defect in Tcell subsets was detected and it was suggested that continuous regulation of iron balance is an important factor in decreasing immunological disturbance.
کلیدواژه‌های انگلیسی مقاله Beta thalassemia major, T cell subsets,

نویسندگان مقاله 40140---40141---

نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/viewArticle/705
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زبان مقاله منتشر شده en
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