|
|
1393/2/3، جلد ۲۰۱۴، شماره ۴، صفحات -
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژههای فارسی مقاله |
|
|
| عنوان انگلیسی |
Folate and homocysteine levels and their relationship with dietary intakes in Iranian helicobacter pylori infected patients and healthy subjects, a case- control study |
|
| چکیده انگلیسی مقاله |
Abstract- The relationship between HP (HP) infection and the concentration of folate or homocysteine is still unclear. The aim of the present study is to assess the effect of HP infection on folate and homosysteine concentrations in HP infected and healthy subjects. We also assessed dietary intakes of folate, vitamins B 6 and B 12 in two groups. In this case-control study, 44 subjects with Hp-infection and 46 healthy controls were studied. Participants were recruited from the patients referred to the central laboratory of Tabriz university of medical sciences. Blood samples were collected to determine serum folate and homocysteine levels. The presence of both IgG and IgA in serum was considered as HP positive. Dietary intakes were assessed in all subjects by 24-hour dietary recalls by trained interviewers for 3 days. The mean concentration of serum folate was significantly lower in Hp-positive patients than in controls (8.49 nmol/L vs. 10.95 nmol/L, respectively; P=0.01). Although the mean concentration of serum homocystein differed between groups, statistical significance was missed (HP infected patients: 9.35 µmol/L; healthy subjects: 8.96 µmol/L; p=0.064). Macro- and micronutrient intakes showed no significant difference between participants with and without HP infection. In logestic regression models, there was a negative relationship between folate concentration and HP infection even after controlling for confounding factors (OR=0.82; 95%CI=0.79-0.97). In this study, we showed that there was a negative relationship between HP infection and serum folate levels but the homocysteine status was not differed significantly between HP-positive and HP-negative subjects. |
|
| کلیدواژههای انگلیسی مقاله |
Folate; homocysteine; Helicobacter pylori |
|
| نویسندگان مقاله |
40485---40486---40487---40488--- |
|
| نشانی اینترنتی |
http://acta.tums.ac.ir/index.php/acta/article/viewArticle/5372 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
|
| نوع مقاله منتشر شده |
Original Article(s) |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|
