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1393/8/5، جلد ۱۴، شماره ۱، صفحات -
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عنوان فارسی |
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چکیده فارسی مقاله |
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کلیدواژههای فارسی مقاله |
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عنوان انگلیسی |
Flow Cytometry Applications in the Study of Immunological Lung Disorders |
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چکیده انگلیسی مقاله |
Normal 0 false false false EN-US X-NONE AR-SA The use of flow cytometry in the clinical laboratory has grown substantially in the past decade. Flow cytometric analysis provides a rapid qualitative and quantitative description of multiple characteristics of individual cells. For example, it is possible to detect the cell size and granularity, aspects of DNA and RNA content and the presence of cell surface and nuclear markers which are used to characterize the phenotype of single cells. Flow cytometry has been used for the immunophenotyping of a variety of specimens including whole blood, bone marrow, serous cavity fluids, (cerebrospinal fluid) CSF, urine and all types of body fluids. The technique has also been applied to human bronchoalveolar lavage (BAL) fluid, peritoneal fluids and blood. In this review, we describe the current status of the application of flow cytometry as a diagnostic tool in various lung diseases. We focus on the analysis of BAL cell composition in chronic obstructive lung disease (COPD), asthma, lung cancer, sarcoidosis, tuberculosis and idiopathic eosinophilic pneumonia (IEP). |
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کلیدواژههای انگلیسی مقاله |
Asthma; Broncho alveolar lavage (BAL); COPD; Flow cytometry; Lung disease; Sarcoidosis |
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نویسندگان مقاله |
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نشانی اینترنتی |
http://ijaai.tums.ac.ir/index.php/ijaai/article/viewArticle/1096 |
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زبان مقاله منتشر شده |
en |
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نوع مقاله منتشر شده |
Articles |
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