Idiopathic (primary) hyperhidrosis is defined as an excessive sweating with no clear cause and usually results in social, psychological, and professional disturbances.

In this study, tap water and normal saline iontophoresis were used in a 21-year-old female suffering from severe idiopathic palmoplantar hyperhidrosis.The result of 8 sessions iontophoresis showed that tap water and normal saline iontophoresis are effective in treatment of idiopathic hyperhidrosis. However, in contrast with other studies, normal saline iontophoresis was twice more effective than tap water iontophores. Quality of life of the patient was improved.