Introduction: There are risk of fire accidents in Operating rooms during surgery. Experts estimate annually around 100 fire accidents occur in the operating rooms of United States’s hospitals. 10 to 20 of these accidents lead to severe injuries and about 1 to 2 lead to death. Despite such accidents rarely happen, but they can lead to serious injury or death of patients.

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Material and Method: This Cross-sectional questionnaire based survey was conducted among several hospitals belonged to Shiraz University of Medical Sciences. In this study, all personnel of operating rooms were investigated. Questionnaire were used to collect information and the chi-square test was applied to examine the relationship between the Knowledge of operating room personels on fire prevention and control methods, jobs and work experience. For statistical analysis SPSS14 were used.

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Result: In this study from 220 participants, about 19.72% had full awareness, 19.62% had partial knowledge, 19.37% had low awareness and 40.97% had no knowledge on fire prevention methods, concerning fire control methods. However, 76% of the participate had full awareness and 24% had no knowledge. Test result Statistically showed that the relationship between the awareness of operating room personnel to fire control methods and work experience were significant (P-value <0.05). But, the relationship between the knowledge of operating room to fire control methods and the type of jobs were not significant. Also no significant relationship were found between the level of awareness in operating room personnel to fire prevention methods, work experience and job title.

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Conclusion: The results indicated that the operating room staff awareness of fire prevention and control methods are low. The results also showed that awareness of fires prevention are lower than the awareness of fire control among the studied personel. Regarding to the potential risk of fire in the operating room, it is suggested that in order to increase awareness of vulnerable patients and personnel in operating conditions, measures like educational need assessment, training workshops on fire prevention and control methods should be implemented.