Introduction: Eye discomforts and headache are prevalent among computer users. The aim of present study was to determine eye discomforts and headache associated with computer use among dormitory students of Tehran University of Medical Sciences.

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Material and Method: In this cross – sectional study, data were collected using MIRTH (Musculo skeletal Injury Reduction Tools for Health and Safety) questionnaire. The results were Analyzed using SPSS Software and with descriptive statistical indexes as well as correlation test.

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Result: of the 744 distributed questionnaires, 631 students completed the questionnaire (84.4%). The mean age for the studied population was 22.72± 3.6 years. The relative frequency of eye discomforts for the female and male student was 76.38% and 70.11% respectively. The correlation test showed significant relationship between eye discomforts as well as headache with gender, work hours’ with a computer per day and glass use (P-V < 0.05). Also, the correlation between eye discomforts and headache was statistically significant (P-V < 0.01).

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Conclusion: Eye discomforts and headache relating to the computer uses are prevalent among students. The condition is more prevalent among females and prolonged computer users. Interventional and training programs should be considered to prevent and reduction of related problems.