1392/2/28، جلد ۵، شماره ۲، صفحات -

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عنوان انگلیسی Helicobacter pylori infection and pediatric asthma
چکیده انگلیسی مقاله Objective: Childhood infectious diseases are one of the most known environmental pathogenic causesof childhood asthma. The high prevalence of both Helicobacter pylori infection and asthma in our country prompted us to assess anyprobable association between them in childhood. Methods : This cross-sectionalstudy recruited 196 children aged 6 to 12 years old comprising 98 asthmatic (case group) and 98 healthy (control group) individuals. Urea breath test was performed for all of the children and H. pylori infection was compared between the two groups according to the urea breath test results. Results :Urea breath test was positive in 18 asthmatic (18.36) and 23 (23.36) healthy subjects but was not significantly different between the case and controls(p=0.380).Furtheranalysis in the asthmatic group revealed association of H. pylori infection withage (p<0.001) and duration of asthma (p=0.010). However, no significant correlation was found between sex, severity of asthma, controledasthma  or abnormal pulmonary function testswith H. pylori infection (p= 0.804, 0.512 ,0.854 and 0.292, respectively). Conclusion :Given the results of the study, H. pylori infection was not significantly differentbetween asthmatic and healthy children.In asthmatic patients, there wasnosignificant association between H.pylori infection andsex,severity of disease, control status of disease andnormal or abnormal pulmonary function tests. H. Pylori infection had a significant association withincreasing age and duration of asthma.  
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نویسندگان مقاله 51754---51755---51756---51757---51758---51759---

نشانی اینترنتی http://ijm.tums.ac.ir/index.php/ijm/article/viewArticle/365
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