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1388/7/8، جلد ۱، شماره ۳، صفحات -
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
Cross-sectional study of extended spectrum beta-lactamase producing gram-negative bacilli from clinical cases in Khorramabad, Iran |
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| چکیده انگلیسی مقاله |
Introduction: Antibiotic resistance among bacteria in particular those producing Extended Spectrum Beta lactamases (ESBLs)has a very significant role in hospital acquired infections. Some of the gram negative bacilli including Klebsiella pneumoniaand Escherichia coli are known to be ESBL producers which cause uncontrollable infections because they are also oftenresistant to other antimicrobial agents. This study was designed to assess the ESBL producing gram-negative bacilli amongclinical isolates of inpatients at Shohada-ye Ashayer Hospital, Khorramabad, Iran. Materials and Methods: Samples were processed with routine laboratory methods and gram-negative bacilli were identifiedby standard tests. ESBL producing gram-negative bacilli were screened by MacConkey Agar containing 4 mg/liter ceftazidimeand confirmed with the double disk synergy method. Results: Fifty-three cases (23.6%) of 225 total isolated gram-negative bacilli were positive in terms of ESBL production.Klebsiella pneumoniae comprising 20 cases (8.9%) was the dominant organism producing ESBLs followed by Escherichiacoli (10 cases; 4.4%) and Pseudomonas aeruginosa (10 cases; 4.4%). The most ESBL producing organisms were found inurine samples (21 cases; 39.6%). Ten cases (18.9%) of isolates were from samples collected with sterile bronchoscopy. Conclusion: Results of the study indicated that ESBL producing gram negative bacilli are frequently isolated from ShohadayeAshaier Hospital. Regarding the high resistance of these strains against many of the antibiotics and even against carbapenems,health care professionals need to plan policies to fight the induction and spread of such strains |
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| کلیدواژههای انگلیسی مقاله |
Hospital acquired infection, Escherichia coli, Klebsiella pneumoniae, ESBL, Khorramabad, Iran |
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| نویسندگان مقاله |
52222---52223---52224--- |
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| نشانی اینترنتی |
http://ijm.tums.ac.ir/index.php/ijm/article/viewArticle/24 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Articles |
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