1393/6/17، جلد ۹، شماره ۳، صفحات -

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عنوان انگلیسی Morphological and Genetic Characteristics of the Liver Hydatid Cyst of a Donkey with Iran Origin
چکیده انگلیسی مقاله Abstract Background: No data is available on morphology and genetic characteristics of Echinococcus granulosus derived from donkeys of Iran, despite of its existence in don­keys. In the present study morphometric variations of the rostellar hooks of protoscole­ces and genotype characteristics of hydatid cyst of donkey from Iran were determined. Methods: Protoscoleces prepared from hydatid cyst of donkey of Iran were morpho­metric and genetic analyzed. The genetic analysis was done using Cox 1 gene by comparative sequence analysis. Results: Our morphometric results showed that donkey of Iran shares 6 out of 7 determined parameters with donkeys of Jordan and 4 out of 7 with 4 available data with Switzerland donkeys. Morphological similarities and dissimilarities were ob­served with sheep-dog (G1) and camel-dog strains (G6) of Iran. The nucleotide sequence alignment showed that the partial sequence of Cox 1 from donkey had 91% homology with query coverage of 99% to the corresponding sequence of E. equinus , 90% homology to the E. felidis , 90% homology to E. ortleppi , 89% homol­ogy to the E. shiquinus , 89% homology to the E. vogeli , 89% homology to the E. oligarthrus , 88% homology to the E. canadensis and 83% homology to the Taenia so­lium . Additionally, the amino acid sequence of this gene has also some differences between this strain and all known strains of E. granulosus even with E. equinus (G4). Conclusion: Despite of common morphological characteristics of Iranian donkey hydatid cyst with those of donkeys of other parts of the world, genetically it has its own entity. Keywords: Echinococcus granulosus , Morphometric, DNA, COX I, Donkey, Iran
کلیدواژه‌های انگلیسی مقاله Keywords: Echinococcus granulosus , Morphometric, DNA, COX I, Donkey, Iran

نویسندگان مقاله 53860---53861---53862---

نشانی اینترنتی http://ijpa.tums.ac.ir/index.php/ijpa/article/viewArticle/1301
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