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1391/12/15، جلد ۵، شماره ۲، صفحات -
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
The relationship between patent foramen ovale (PFO) and migraine headache |
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| چکیده انگلیسی مقاله |
Introduction: Migraine is defined as an often familial symptom complex of periodic attacks of vascular headache, usually temporal and unilateral in onset. Approximately 12% of population or 27 million people in the United States alone have migraine headaches. Many studies have been done to evaluate different risk factors for migraine headaches. Recently, the probable association between migraine with aura and right to left shunts has been found. These shunts are usually across a large patent foramen ovale (PFO). Objectives: The aim of this study was to evaluate the prevalence of PFO among migraineurs by means of Transcranial Doppler Ultrasonography (TCD). Methods: A total of 56 migraine patients consecutively admitted to the neurology outpatient clinic of Firouzgar hospital were studied. The diagnosis of migraine was based on the criteria adopted by the International Headache Society (IHS). All the migraineurs underwent TCD in order to detect PFO in their atrial septum. Subsequently, Transesophageal Echocardiography (TEE) was done in migraineurs with TCD evidence of PFO. The data were analyzed using SPSS v.13 software. Chi 2 'Independent T-test and Mann- Whitney U-test were used in analysis. Results: The mean age of the patients was 30.75(SD=1.17) years. The migraineurs were 14(25%) males and 42(75%) females. Additionally, 26(46.4%) had migraine with aura and 30(53.6%) had migraine without aura. The result of TCD shows that the prevalence of PFO was 32.1% (18 out of 56) in migraineurs; which is significantly higher than normal population (20%, P=0.023). By the way, the prevalence of PFO was higher in migraineurs with aura (38.5%) than migraineurs without aura (23.7%). PFO was confirmed in 14 out of 18 (77.8%) migraineurs with aura by means of TEE. Conclusion: PFO is more common in patients with migraine headache especially in migraineurs with aura. The association between migraine with aura and PFO suggests that the two entities are comorbid and may share a similar inheritance pattern. Many migraineurs may also benefit a significant improvement in frequency of headache attacks following PFO closure. Keyword: Migraine, Patent Foramen Ovale (PFO), Transcranial Doppler Ultrasonography (TCD) |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
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| نشانی اینترنتی |
http://ijnl.tums.ac.ir/index.php/ijnl/article/viewArticle/216 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Original Article(s) |
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