|
|
1391/12/15، جلد ۵، شماره ۲، صفحات -
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Serum testosterone level study in multiple sclerosis patients |
|
| چکیده انگلیسی مقاله |
Background: Multiple sclerosis (MS) is the most common demyelinating disease. Autoimmune basis have been confirmed for the pathogenesis. Testosterone (TES) has the role in these immune mechanisms. Its serum level in MS had significant changes in other reports. The purpose of this study is to survey these changes in patients. Materials & Methods: In this cross sectional study 50 MS patients were selected for TES study. The same number of controls with sex and age matching were studied. Special diseases and drug users were excluded from our study. RIA was used for serum level determination of hormones. Results: In TES level survey, male patients had lower level of TES than controls significantly (3.01±1.45ng/ml versus 5.59±1.28ng/ml, P value< 0.0001). TES level female patents' had not significant changes. Conclusion: According to studied changes an hormone, TES have negative relation with MS in male patients. Further study for determination of causality relation and drug effect in endocrine system in MS pathogenesis are suggested. Keyword: Multiple Sclerosis, Testosterone, Male, Female |
|
| کلیدواژه‌های انگلیسی مقاله |
|
|
| نویسندگان مقاله |
55354---55355---55356---55357--- |
|
| نشانی اینترنتی |
http://ijnl.tums.ac.ir/index.php/ijnl/article/viewArticle/217 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
|
| نوع مقاله منتشر شده |
Original Article(s) |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|
