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1391/12/15، جلد ۵، شماره ۲، صفحات -
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Comparison of the effects of anti-helicobacter pillory versus classic anti-migraine drugs in decreasing the frequency of migraine attacks among the migraine's patients with seropositive helicobacter pitter infection |
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| چکیده انگلیسی مقاله |
Introduction: Migraine is a common disease with prevalence 18.2% in women and 6.5% in men. Recent studies have suggested an association between Helicobacter pylori and migraine and also usefulness of the eradication treatment on headache. The aim of the present study was to assess effect of H.P eradication versus effect of classic anti migraine drug on severedity and frequency and disability of migraine headache. Materials and Methods: A total 63 consecutive patient with migraine (with & without aura) with serologic evidence of HP infection divided to 3 equal groups (21subject) and were matched for sex and age and treated by 3 modality (Anti HP drugs, classic anti migraine drugs and combination of two drugs). HP infection was assessed by ELISA evaluation of specific IgG antibody and eradication control of HP was made by ELISA again after 6 month. The diagnosis and classification of migraine was made according to International headache society (HIS) criteria. Ne assessed the frequency and severity of clinical attacks of migraine according by MIDAS questionnaires before and after 3 modality of treatment during 6 month period of observation. Results: Approximately 66.7 of subject treated with Anti HP drugs had MIDAS score below 5 versus 61.7% of patients received classic anti migraine drugs (P<0.001). MIDAS Grad equal or less 2 observed in all eradicated patients. Effect of combination therapy was higher than effect of each therapy alone (P=0.015) and 81%of patient received combination therapy had MIDAS Grade equal one. Conclusion: Our study suggests H.P should be examined in migranous patients and eradication of the infection may be helpful for the treatment of the disease & effect of combination therapy is better. Keyword: Migraine:Helicobacterpylori, Midas, Treatment |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
55362---55363--- |
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| نشانی اینترنتی |
http://ijnl.tums.ac.ir/index.php/ijnl/article/viewArticle/219 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Original Article(s) |
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