| چکیده انگلیسی مقاله |
Background: Lead toxicity is a medical problem in Iran. Therefore we aimed to evaluate clinical findings and possible complications of lead poisoning in the workers of two traditional-tile-factories. Materials and Methods: Researchers visited workers in the factories and collected data by direct history taking and physical examinations. data were recorded in previously designed forms. Blood sampling was performed for biochemical, toxicological and hematologic studies. Blood and Urine lead concentration were measured by an atomic absorption technique (Heated Graphite Atomisation) using Perkin-Elmer 3030 instrument. Data were analyzed by SPSS-11.5 software and Chi-square, student T-test and Pearson correlation tests were used accordingly. The numerical data were expressed as mean x standard deviation. Results: Overall 108 male subjects ages 37±7.8 years were studied. Length of daily lead exposure was 9.8±6 years. Lead concentration in 2004 and 2005 were 520.5±323.2 and 361.5±176.9 mg/L, respectively. The subjective findings were mainly on the central nervous system such as loss of memory (57%), moodiness (56.1%), agitation (47.7%), drawsiness (36.4%), headache (29.9%).The main objective clinical findings were peripheral neuropathy of upper limb (37%), suppression of deep tendon reflexes in upper limbs (25.7%), tremor (23.3%), peripheral neuropathy of lower limbs (17%). Conclusion: This study showed that lead has toxic effects on the teeth (bone), central and peripheral nervous system, hematologic and renal function, and also changes in serum lipid concentration. Keyword: Occupational Toxicity, Lead, Poisoning, Traditional Tile Factory, Neuropathy |
