1391/12/10، جلد ۸، شماره ۲، صفحات -

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عنوان انگلیسی Neuromyelitis optica mimicking multiple sclerosis-presentation of two cases
چکیده انگلیسی مقاله Introduction: Neuromyelitis optica (NMO) or devic disease is a relatively uncommon neurologic disease that often mimicks multiple sclerosis (MS) in clinical practice. It usually presents with recurrent attacks of optic neuritis and myelitis but unlike MS the attacks are often associated with some degrees of sequelae and there is no involvement of nervous system outside of the optic nerves and spinal cord particularly in the earlier phase of the disease. the constellation of findings including characteristic clinical behavior, imaging findings of the brain and spinal cord and the recent finding of antibody against aquaporin-4 water channels differentiates this disease from MS. Response of the attacks to corticosteroid may be inadequate and we may need plasma exchange for better symptomatic remission of acute attacks. To prevent further attacks, prophylactic treatment with immunosuppressive agents may be helpful. Two cases of NMO with characteristic clinical and neuroimaging features are presented that mimicked MS at first and with good response to plasma exchange despite the inadequate improvement following corticosteroid pulse therapy. Keyword: NEUROMYELITIS OPTICA-MULTIPLE SCLEROSIS-OPTIC NEURITIS-MYELITIS-CORTICOSTEROID PLASMA EXCHANGE
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نویسندگان مقاله 56153---56154---

نشانی اینترنتی http://ijnl.tums.ac.ir/index.php/ijnl/article/viewArticle/153
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