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1392/9/30، جلد ۲، شماره ۱، صفحات -
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
Effect and properties of surface-modified copper doped ZnO nanoparticles (Cu:ZnO NPs) on killing curves of bacterial pathogensBackground Nanoparticles have significant potential for their usefulness in biological applications particularly their antimicrob |
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| چکیده انگلیسی مقاله |
Abstract Background Nanoparticles have significant potential for their usefulness in biological applications particularly their antimicrobial activity. The current study aimed to determine the e ffect and properties of surface-modified copper doped Cu:ZnO NPs . Materials and Methods Preparation of in situ surface-modified copper doped ZnO nanoparticles (Cu:ZnO NPs) was done according to standard procedure. Assay for antimicrobial activity of Cu:ZnO NPs against bacterial pathogens was carried out based on disc diffusion method. Determination of shelf life, thermal and pH stability of antibacterial activity of Cu:ZnO NPs was done and residual activity was determined against the target cultures. Results FTIR spectra indicate that the nanomaterials synthesized have higher peak intensity compared with reagent grade ZnO. According to the SEM image the nanoparticles synthesized have different size and heterogeneous morphology; among them nanorods and spherical nanoparticles are more obvious. 400 ppm of Cu:ZnO NPs gave zones of inhibition with diameters of 9.0 – 16 mm against the target cultures. Amongst the target cultures, E. coli was the most sensitive to the Cu:ZnO NPs inhibition zone diameter 16 mm; whereas, 9 mm wide inhibition zone was obtained against S. aureus . The Cu:ZnO NPs was fairly stable for a period of 60 days at room temperature (RT) showing lost of only 20% and 30 % antibacterial activity as tested against E. coli and S. aureus respectively (data not shown). Stability of Cu:ZnO NPs at different pH (5-9) and temperature (40-70 0 C) was checked. The Cu:ZnO NPs was quite stable at this pH and temperature range tested against both E. coli and S. aureus . Conclusion Surface-modified copper doped Cu:ZnO NPs have significant potential for their usefulness as antibacterial agents. Key words : Cu:ZnO NPs, antibacterial, properties. Normal 0 false false false EN-US X-NONE AR-SA |
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| کلیدواژههای انگلیسی مقاله |
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| نویسندگان مقاله |
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| نشانی اینترنتی |
http://jmb.tums.ac.ir/index.php/jmb/article/viewArticle/113 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Original Articles |
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