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1392/9/30، جلد ۲، شماره ۱، صفحات -
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
Antimicrobial effect of Nano-Zinc Oxide and Nano-Chitosan particles in Dental Composite used in Orthodontics |
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| چکیده انگلیسی مقاله |
Background: Incidence of white spots due to demineralization of enamel and gingival problems is an unacceptable result of orthodontic treatment . Plaque accumulation and bacterial biofilm growth are responsible for these phenomenons. The resin-based dental composites used as bonding agents in orthodontics play a major role in mentioned problems. As recent researches assert the antimicrobial effects of chitosan(Cs) and zinc oxide(ZnO) nanoparticles(NPs), it seems that adding these nanoparticles to the composite can be beneficial in reducing the number and function of microorganisms. Methods : Antibacterial effectiveness of ZnO-NPs and CS-NPs was assessed in four groups against Streptococcus mutans , Streptococcus sanguis and Lactobacillus acidophilus grown both planktonic and as biofilm on composites. One group as the unmodified control group and three groups consisting of three different concentrations of ZnO-NPs and CS-NPs mixture : 1%, 5% and 10% (1:1 w/w). 10 8 CFU/ml microorganism suspensions were provided with spectrophotometer. Biofilm formation was quantified by viable counts. Disc Agar Diffusion test was carried out to determine antimicrobial effects of nanoparticles by measuring the inhibition diameter on BHI plates. And finally viable counts of microorganisms on days 3, 15 and 30 were collected for the antimicrobial effects of eluted components from composite discs. Results : In biofilm formation test a reduction in bacterial counts was observed with 10% nanoparticle-containing composites compared with their unmodified counterpart . In the disc agar diffusion test only 10% nanoparticle-containing specimens showed statistically significant inhibition . The only noticeable data in eluted component test was on day 30 for 10% nanoparticle-containing discs, inhibiting L. acidophilus. Conclusion: It seems that mixture of ZnO-NPs and CS-NPs has induced an antibacterial activity in resin composite; especially in 10% weight concentrations which was significantly higher than other groups . Keywords: nano-chitosan, nano-zinc oxide, antimicrobial |
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| کلیدواژههای انگلیسی مقاله |
Keywords: nano-chitosan, nano-zinc oxide, antimicrobial |
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| نویسندگان مقاله |
57103---57104---57105---57106---57107--- |
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| نشانی اینترنتی |
http://jmb.tums.ac.ir/index.php/jmb/article/viewArticle/140 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Original Articles |
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