1391/12/2، جلد ۴۲، شماره ۲، صفحات -

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عنوان انگلیسی The Present Status of Cutaneous Leishmaniasis in a Recently Emerged Focus in South-West of Kerman Province, Iran
چکیده انگلیسی مقاله Background: The objective of this study was to assess the magnitude of the cutaneous leishmaniasis (CL) disease and identification of the causative agent by nested-PCR for current control strategy. Methods: This study was carried out as descriptive house-to-house visits in Orzoieh district in Kerman Province, south?east Iran, during 2011-2012. A questionnaire was completed for each individual consisting of demographic and clinical data. Suspected individuals were examined by direct smear microscopy and subsequent identification by nested-PCR. X 2 -test was used for any significance ( P <0.05). Results: A total of 18308 inhabitants (mean age; 22.7 yr) consisting of 9011 males (49.2%) and 9297 females (50.8%) were examined for the presence of active or chronic lesions. The overall prevalence was 4.7%, including 30 cases of active and 839 cases of scar, distributed more significantly ( P <0.01) in females (5.2%) than males (4.3%). Individuals <10 years of age showed the highest (6.3%) and >50 years the lowest rate of CL disease, respectively ( P <0.001). The proportion of infection was the highest in Soltanabad (14.7%), followed by Vakilabad (6.8%), Dolatabad (3.2%) and Shahmaran (2.8%). The majority of cases had 2 lesions (mean; 2.1 lesions). Hand was the most common site of involvement (35%), and then face (26%), and multiple locations (39%). Nested-PCR displayed 29 isolates as Leishmania major and one isolate L. tropica . The CL disease first emerged in 1998 as epidemic in the area and appeared endemics, thereafter. Conclusion: L. major was the sole species caused ZCL. These findings are necessary for future control programs and strategic planning.
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نویسندگان مقاله 1112---1113---1114---1115---1116---

نشانی اینترنتی http://ijph.tums.ac.ir/index.php/IJPH/article/viewArticle/2763
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