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1392/2/23، جلد ۴۲، شماره ۵، صفحات -
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Gastrointestinal Helminth Infection in Pregnancy: Disease Inci-dence and Hematological Alterations |
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| چکیده انگلیسی مقاله |
Background: The incidence and hematological effects of helminth infection during pregnancy were investigated among pregnant women in Isiala, Mbano, Southeast Nigeria. Methods: Totally 282 pregnant women were enlisted for the study between October 2011 and September 2012.? Stool samples were examined for intestinal helminths using formalin-ether sedimentation technique. Hemoglobin (Hb) and Packed Cell Volume (PCV) levels were evaluated in venous blood samples using Sahli?s and microhaematocrit methods respectively. Results: Forty six (16.3%) subjects were infected with at least one helminth parasite; 24 (8.5%) hookworm, 14(5.0%) and 2(0.7%) A . lumbricoides and Trichuris trichiura infections respectively. Intestinal helminthiases in pregnant women was significantly associated with age ( P <0.05). The prevalence of intestinal helminthiases by parity was also significantly different ( P <0.05) with primigravidae having the highest infection rate (27.5%). Hematological assessment showed that the prevalence of anemia among the women was 58.9% (mean?SD = 9.3?1.0). The differences in hemoglobin levels by age groups was statistically significant ( P <0.05). The contributory effect of gastrointestinal helminths in anemia showed that infected pregnant women had lower mean hemoglobin (8.60?0.22g/dl) than the uninfected (9.72?0.07g/dl). Significant difference ( t -value = 5.660, P <0.05) was observed between the Hb of the infected and uninfected pregnant women. In addition, infected pregnant women had mean PCV of 26.09?0.65% while the uninfected had 34.54?2.96%. The mean PCV of infected pregnant women was significantly different ( t -value= 0.013, P <0.05) from that of the uninfected. Conclusion Anti-helminthic therapy after the first trimester should be part of the antenatal programme. Intestinal helminth infection showed significant negative correlation with Hb and PCV and contributed moderately to anemia. Keywords: Anemia, Hematology, Hookworm, Hemoglobin, Packed cell volume |
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| کلیدواژه‌های انگلیسی مقاله |
Keywords: Anemia, Hematology, Hookworm, Hemoglobin, Packed cell volume |
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| نویسندگان مقاله |
1169---1170---1171---1172--- |
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| نشانی اینترنتی |
http://ijph.tums.ac.ir/index.php/IJPH/article/viewArticle/3197 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Articles |
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