1392/2/23، جلد ۴۲، شماره ۵، صفحات -

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عنوان انگلیسی Immunoglobulin A Nephropathy and Malaria falciparum Infection; a Rare Association
چکیده انگلیسی مقاله Glomerular involvement occurs as a rare form of renal manifestation in Plasmodium falciparum malaria. Here, we report a rare case of falciparum malaria-associated IgA nephropathy. A 28-year-old man was admitted because of fever and abdominal pain. Ultrasound and computed tomography (CT) showed right kidney pyonenphrosis. Despite placing a nephrostomy tube, fever continued. Repeated CT was in favor of focal pyelonephritis. In addition, peripheral blood smear suggested malaria. Anti-malarial drugs were initiated and right nephrectomy was performed. One year after recovery from malaria, a persistent rise in serum creatinine was detected. A left kidney biopsy showed mesangial proliferation and dominant IgA deposits in immunofluorescence study while C 1 q was not deposited. The impression was IgA nephropathy with M 1 E 0 S 0 T 0 of Oxford classification. The patient was prescribed a combination of low dose prednisolone and angiotensin converting enzyme inhibitor. Six months after treatment serum creatinine decreased from 1.6 mg/dL to 1.3mg/dL and urine abnormalities were disappeared. Our findings suggest that malaria infection might be associated with IgA nephropathy. Keywords: IgA nephropathy, Malaria, Plasmodium falciparum
کلیدواژه‌های انگلیسی مقاله Keywords: IgA nephropathy, Malaria, Plasmodium falciparum

نویسندگان مقاله 1192---1193---1194---1195---1196---

نشانی اینترنتی http://ijph.tums.ac.ir/index.php/IJPH/article/viewArticle/3203
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