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1391/7/22، جلد ۴، شماره ۳، صفحات -
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
The Association Between Hypothyroidism and Anemia: a Clinical Study |
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| چکیده انگلیسی مقاله |
Introduction: Hypothyroidism is diagnosed by elevated thyroid stimulating hormone (TSH) and normal or decreased serum levels of T4 or T3, and is associated with a wide range of m etabolic abnormalities, including anemia. This clinical study aimed to assess the improvement of anemia in patients with primary hypothyroidism following administration of levothyroxine in Iranian population. Materials & Methods: The effect of levothyroxine in 70 patients with hypothyroidism was examined and the improvement of anemia in patients who had a poor or good response to levothyroxine was assessed during a 3 month follow-up. Results: Three months after treatment, the levels of TSH in 64 patients with hypothyroidism (91.4%) significantly decreased to a normal limit (TSH< 2.5 IU/ml). Forty three out of 70 patients (61.4%) had a concurrent anemia. A significant difference was found in the levels of hematologic parameters between those who had a good response (TSH< 2.5 IU/ml) and those with poor responses to the treatment (TSH ≤ 2.5 IU/ml) (p< 0.05). Conclusions: Current study showed a high rate of association between anemia and hypothyroidism in Iranian population. Improvement in hypothyroidism and its associated anemia was observed in majority of patients (more than 90%), indicating a dual benefit for hypothyroidism treatment. Less than 10% of patients poorly responded to levothyroxine, with no clear reasons. |
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| کلیدواژه‌های انگلیسی مقاله |
Anemia, Hypothyroidism, Iran, Levothyroxine, |
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| نویسندگان مقاله |
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| نشانی اینترنتی |
http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/viewArticle/249 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Articles |
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