Background and Aim: Furcal perforation has a great impact on prognosis of endodontic treatments, requiring immediate and proper intervention. Gray MTA is applied as material of choice in repairing perforations. The aim of this study was to evaluate the repair of mechanical furcal perforations, histologically using white MTA and Portland cement and compare them with gray MTA.

Materials and Methods: In this experimental study, second to fourth mandibular and maxillary premolar teeth of five dogs received endodontic treatment, then the furcation area of the teeth were perforated and repaired as follow: gray MTA in group1, white MTA in group 2, Portland cement in group 3 and cotton pellet in group 4 (control). Animals were controlled for 4 months and sacrificed using an over dosage of sodium thiopental intravenous injection and perfusion of 10% formaldehyde. Chi-square and Fisher exact tests were used to compare hard tissue formation between groups and between each two groups, respectively. Non-parametric Kruskall Wallis and Dunn procedure were also used to compare degree of inflammation among groups and between each two groups, respectively.

Results: Gray MTA had more favorable results (90.9% hard tissue formation and only 9.1% severe inflammation) but the difference between gray MTA, white MTA and Portland cement was not statistically significant.

Conclusion: The difference between gray MTA, white MTA and Portland cement groups was not statistically significant for degree of inflammation and hard tissue formation. In conclusion both white MTA and Portland cement can be used instead of gray MTA to repair perforations in accordance to esthetic considerations.