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1390/8/21، جلد ۶، شماره ۱، صفحات -
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عنوان فارسی |
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چکیده فارسی مقاله |
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کلیدواژههای فارسی مقاله |
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عنوان انگلیسی |
Evaluation of Longitudinal Right Ventricular Mechanical Dyssynchrony before and Early after Cardiac Resynchronization Therapy: A Strain Imaging Study |
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چکیده انگلیسی مقاله |
Background: The right ventricular (RV) dyssynchrony has not been studied extensively and the existing literature has established the effect of cardiac resynchronization therapy (CRT) on the left ventricular (LV) dyssynchrony, but there is a dearth of data on the effect of CRT on the forgotten ventricle. We sought to evaluate the presence of mechanical right ventricular dyssynchrony in patients with systolic heart failure, selected for CRT, and track the changes early afterward utilizing the longitudinal strain analysis. Methods: Thirty-six patients with severe left ventricular systolic dysfunction, candidated for CRT, were enrolled in this study. Mechanical dyssynchrony was assessed using tissue Doppler echocardiography. The time interval between the onset of the QRS to the peak systolic longitudinal strain at the RV free wall and the septum was obtained. The RV mechanical delay was calculated as the absolute value of the difference in the time-to-peak measurements between the RV and septum. The RV dyssynchrony was defined as the calculated delay in strain imaging, which was ± 2 SD above the mean value for the control subjects (20 cases). The RV function was evaluated using the RV fractional area change (RVFAC), tricuspid annulus plane systolic excursion (TAPSE), and peak systolic strain values of the RV free wall. Four to 7 days after CRT implantation, echocardiographic reevaluations were done. Results: The calculated cut-off value for the RV dyssynchrony was 41.5 msec, according to which the pre-CRT analysis specified two patient groups: Group 1 (16 cases) with RV dyssynchrony and Group 2 (20 patients) without RV dyssynchrony. Significant improvement in the RV dyssynchrony was noted in Group 1 after CRT (30 ± 28.9 msec vs. 68.8 ± 21 msec; p value Conclusion: Early after CRT, the RV mechanical delay can improve and the significant improvement is seen in patients with baseline RV mechanical dyssynchrony. |
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کلیدواژههای انگلیسی مقاله |
Heart ventricles , Cardiac resynchronization therapy , Heart-assist devices , Ventricular function, right |
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نویسندگان مقاله |
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نشانی اینترنتی |
http://jthc.tums.ac.ir/index.php/jthc/article/viewArticle/194 |
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زبان مقاله منتشر شده |
en |
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نوع مقاله منتشر شده |
Original Articles |
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