1387/9/24، جلد ۱۶، شماره ۲، صفحات ۲۸-۳۳
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عنوان انگلیسی Osteoporosis in postmenopausal diabetic women; prevalence and related factors
چکیده انگلیسی مقاله   Introduction: Diabetes mellitus and osteoporosis are two frequent medical conditions with an increasing prevalence in elderly. This study is conducted to evaluate osteoporosis in postmenopausal females with type 2 diabetes mellitus in Sanandaj, the provincial center of Kurdistan province in the west of Iran. Methods: From an initial population of 2500 women with type 2 diabetes, 242 postmenopausal women were randomly selected and were compared with 221 non-diabetic postmenopausal women, matched by age and body mass index (BMI). Bone mineral density (BMD) was measured at the L2-L4 vertebrae (anteroposterior projection) and femoral neck with dual energy X-ray absorptiometry (DXA). The statistical significance was set at a P value of .05 or lower.Results: Prevalence of femoral neck osteoporosis in diabetic women was 30.2 percent (73 cases) and osteopenia was 48.3 percent (117 cases). Osteoporosis prevalence in spine was 7.9 percent (19 cases) and ostropenia was 46.3 percent (112 cases). Osteoporosis in both femoral neck (P=0.001) and spine (P=0.04) were significantly higher in patients than in controls. Correlation between HbA1c and femoral neck (p=0.11, correlation coefficient=0.04) and also spine (p=0.10, correlation coefficient= -0.12) T score was not significant. No significant correlation was found between osteoporosis with presence of microalbuminuria (P=0.91), retinopathy (P=0.33), hypertension (P=0.70), ischemic heart disease (P=0.57) and insulin therapy (P=0.08).Conclusion: This study shows that type 2 diabetic patients have significantly lower T score values and more frequency of osteoporosis than healthy postmenopausal women.
کلیدواژه‌های انگلیسی مقاله Iran, meta-analysis, trend of infertilityGated myocardial perfusion SPECT, Quantification, segmental scoring, Meckel’s scan, Meckel’s diverticulum, Gastrointestinal bleeding, Technetium Pertechnetate scintigraphy, Thiosemicarbazone, 191Os, Radiolabeling, Biodistribution, RBBB, Myocardial perfusion, Gated SPECT, Coronary artery disease, Effective dose, Nuclear medicine procedures, Collective effective dose, Tc99m MIBI parathyroid scintigraphy, Myocardium perfusion gated SPECT, Parathyroid adenoma, Skeletal scintigraphy, Fluid restriction, Tc-99m MDP, Image quality, Bone to soft tissue ratio, Radiology, Nuclear medicine, Medical imaging, Bibliometric study, Iran, Hyperthyroidism, Radioactive iodine, Sexual hormones, Semen analysis, Attenuation correction, Artifact, Color intensity, SPECT, Thyroid, I-131, Absorbed ratio, Monte-Carlo, Absorbed dose, MCNP-4A, Carcinoid Tumor, Liver metastases, ¹³¹I-MIBG scintigraphy, Quality Control, PET, 82mRb, 82Kr, Myocardial perfusion, Drug delivery systems, Gamma-scintigraphy, Neutron activation, Pharmacoscintigraphy, Post stroke dementia, Cerebral perfusion SPECT, ECD, 99mTc-DTPA, Renography, Deconvolution, Renal transit time parameters, Nuclear medicine, PET tracer, Gallium, Copper, Tc-94m, Minimally invasive radio-guided surgery, Hyperparathyroidism, Tc-99m sestamibi, Parathyroid adenoma, Parathyroid hyperplasia, Bombesin, 99mTc, Tumor, HYNIC, Radioiodine therapy, TLD, Thyroid cancer, Absorbed dose, Myocardial perfusion scan, Ischemic heart disease, Risk factors, Demographic data, Military hospital, Evidence based medicine, Nuclear medicine, Evidence based medicine, Nuclear medicine, Critical appraisal, Sensitivity, Specificity, Cavernous hemangioma, Radionuclide imaging, 99mTc-RBC, Attenuation correction, Myocardial perfusion, SPECT, Radio-iodine therapy, Liothyronine, Thermoluminescent dosimeter, Accumulated dose, Exposure rate, 106Ru eye plaque, Dose calculation, Mathematical human eye model, MCNP4C code, Sentinel lymph node, Tc-99m antimony sulfide colloid, Lymphoscintigraphy, Skin marking, Osteoporosis, Type 2 diabetes, Postmenopausal, BMD,
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