1388/10/8، جلد ۱۷، شماره ۲، صفحات ۲۶-۳۳

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عنوان انگلیسی Performance comparison of four commercial GE discovery PET/CT scanners: A monte carlo study using GATE
چکیده انگلیسی مقاله   Combined PET/CT scanners now play a major role in medicine for in vivo imaging in oncology, cardiology, neurology, and psychiatry. As the performance of a scanner depends not only on the scintillating material but also on the scanner design, with regards to the advent of newer scanners, there is a need to optimize acquisition protocols as well as to compare scanner performances on an objective basis. In this study we evaluate and compare the performance of 4 Commercial GE PET/CT cameras, the (i) BGO-based Discovery LS PET/CT (DLS), (ii) the BGO-based Discovery ST PET/CT (DST), (iii) the BGO-based Discovery STE PET/CT (DSTE) and finally (iv) the LYSO-based Discovery RX PET/CT (DRX) scanner using the Geant4 Application for Tomographic Emission (GATE). GATE is an open source Monte Carlo simulation platform developed for PET and SPECT studies and is supported by the OpenGATE collaboration. In accordance with the National Electrical Manufactures Association (NEMA) NU 2-2001 protocols, the validation of models is carried out against actual published measurements and the performance comparison is done for sensitivity, scatter fraction and count rate performance, showing very similar performance compared with published results, thus enabling investigations to better model system performance (e.g. resolution degradation) within the reconstruction task.. The simulated results demonstrate highest sensitivity performance with the DST (though with the highest scatter fraction), and highest NECR performance for the LYSO-based DRX, The results also show that DRX, DLS and DSTE PET/CT cameras have nearly the same amount of scatter fraction.
کلیدواژه‌های انگلیسی مقاله Iran, meta-analysis, trend of infertilityGated myocardial perfusion SPECT, Quantification, segmental scoring, Meckel’s scan, Meckel’s diverticulum, Gastrointestinal bleeding, Technetium Pertechnetate scintigraphy, Thiosemicarbazone, 191Os, Radiolabeling, Biodistribution, RBBB, Myocardial perfusion, Gated SPECT, Coronary artery disease, Effective dose, Nuclear medicine procedures, Collective effective dose, Tc99m MIBI parathyroid scintigraphy, Myocardium perfusion gated SPECT, Parathyroid adenoma, Skeletal scintigraphy, Fluid restriction, Tc-99m MDP, Image quality, Bone to soft tissue ratio, Radiology, Nuclear medicine, Medical imaging, Bibliometric study, Iran, Hyperthyroidism, Radioactive iodine, Sexual hormones, Semen analysis, Attenuation correction, Artifact, Color intensity, SPECT, Thyroid, I-131, Absorbed ratio, Monte-Carlo, Absorbed dose, MCNP-4A, Carcinoid Tumor, Liver metastases, ¹³¹I-MIBG scintigraphy, Quality Control, PET, 82mRb, 82Kr, Myocardial perfusion, Drug delivery systems, Gamma-scintigraphy, Neutron activation, Pharmacoscintigraphy, Post stroke dementia, Cerebral perfusion SPECT, ECD, 99mTc-DTPA, Renography, Deconvolution, Renal transit time parameters, Nuclear medicine, PET tracer, Gallium, Copper, Tc-94m, Minimally invasive radio-guided surgery, Hyperparathyroidism, Tc-99m sestamibi, Parathyroid adenoma, Parathyroid hyperplasia, Bombesin, 99mTc, Tumor, HYNIC, Radioiodine therapy, TLD, Thyroid cancer, Absorbed dose, Myocardial perfusion scan, Ischemic heart disease, Risk factors, Demographic data, Military hospital, Evidence based medicine, Nuclear medicine, Evidence based medicine, Nuclear medicine, Critical appraisal, Sensitivity, Specificity, Cavernous hemangioma, Radionuclide imaging, 99mTc-RBC, Attenuation correction, Myocardial perfusion, SPECT, Radio-iodine therapy, Liothyronine, Thermoluminescent dosimeter, Accumulated dose, Exposure rate, 106Ru eye plaque, Dose calculation, Mathematical human eye model, MCNP4C code, Sentinel lymph node, Tc-99m antimony sulfide colloid, Lymphoscintigraphy, Skin marking, Osteoporosis, Type 2 diabetes, Postmenopausal, BMD, Streptokinase, Gallium-67, Thrombosis, SPECT, Radiopharmaceuticals, Breast uptake, Myocardial perfusion scan, Tc-99m sestamibi, Tc-99m pertechnetate scan, Meckel’s diverticulum, Gastrointestinal bleeding, PET, Sensitivity, SPECT, Spatial resolution, Temporal resolution, Dynamic imaging, Attenuation, Collimator, Random coincidence, Animal imaging, Dual isotope imaging, Time-of-Flight, Artifact, Bone scan, Catheter, PSA, Prostate, RIA, Standard matrix, Human serum, Myocardial perfusion scan, Leptin, BMI, [14C]Clozapine, Radiochemical purity, High performance liquid chromatography, Liquid scintillation spectrometer, Renography, Diuretic, 99mTc-DMSA, Differential renal function, Complications, Dipyridamole, Blood pressure changes, 99mTc-MIBI, Brain SPECT, Brain tumor recurrence, Radiation necrosis, Neuroendocrine tumors, Somatostatin receptors, Targeted therapy, Sm-153, EDTMP, Radiopharmaceutical, Therapy, Biological evaluation, Ursodeoxycholic acid, Hepatobiliary scintigraphy, 99mTc-BRIDA, Infantile jaundice, Neonatal hyperbilirubinemia, Positron emission tomography (PET), Scanner performance, Gate,

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