Tehran University Medical Journal

Background and Aim: Due to the increased usage of carbamazepine, phenytoin and Sodium Valproate, a higher number of intoxication is to be expected. The aim of this Study is demographic evaluation of this agents.

Materials and Methods: In this cross-sectional survey we studied 93 patients who were poisoned with these drugs from July 2003 until July 2004, in Loghman Hakeem hospital, Tehran, Iran.

Results: In this study we found these results: 36.6 % were male and 63.4 % of patients were female mean age of patients were about 24.5 y. twenty nine present (29) % were routinely on these drugs. Mean time between consumption and admission was 6 hours and 56% of them had decreased level of consciousness and 90% had high serum level of drugs. 80% of them showed complications such as respiratory distress, Urinary tract infection and etc and 4.5% of patients admitted in ICU and mortality rate was 2%

Conclusion: Results of this study are compatible with other studies and according to high prevalence of overdose with these drugs we must focus on prevention factors like education for suitable management, good care, psychiatric consult and proper Treatment.