Volume 81, Issue 3 (June 2023)
Tehran Univ Med J 2023, 81(3): 232-238 |
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Taghizadeh A, Pourali L, Joudi M, Makvandi B, Hasanzadeh E, Ahmadi Simab S, et al . Recurrence and survival in early breast cancer subtypes. Tehran Univ Med J 2023; 81 (3) :232-238
URL: http://tumj.tums.ac.ir/article-1-12431-en.html
URL: http://tumj.tums.ac.ir/article-1-12431-en.html
Ali Taghizadeh * 
1, Leila Pourali2 , Mona Joudi1 , Bahareh Makvandi2 , Elahe Hasanzadeh3 , Saeideh Ahmadi Simab4 , Golshid Nouri Hosseini5 , Mehrdad Gazanchian5
1, Leila Pourali2 , Mona Joudi1 , Bahareh Makvandi2 , Elahe Hasanzadeh3 , Saeideh Ahmadi Simab4 , Golshid Nouri Hosseini5 , Mehrdad Gazanchian5
1- Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
2- Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3- Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
4- Buali Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
5- Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
2- Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3- Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
4- Buali Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
5- Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
Abstract: (575 Views)
Background: Breast cancer is the most common type of cancer in many countries, accounting for over 18% of all cancers in females. There are more than one million new cases of breast cancer each year. Most women diagnosed with breast cancer are over the age of 50, but younger women can also get breast cancer. About one in seven women are diagnosed with breast cancer during their lifetime. There's a good chance of recovery if it's detected at an early stage. In Iran, breast cancer is the most common cancer among women, making up 21.4% of all female cancers. The mortality rate of this cancer is 4.33 for every 100,000 people. The purpose of this research is to see how often different kinds of early breast cancer come back and how long people live after being diagnosed.
Methods: This retrospective study evaluated the medical records of 500 breast cancer patients at two hospitals in Mashhad, Iran during April 2006 to March 2016. We used SPSS software, version 16 (SPSS Inc., Chicago, IL, USA) to analyze data. A P value less than 0.05 means that the results are considered statistically significant.
Methods: This retrospective study evaluated the medical records of 500 breast cancer patients at two hospitals in Mashhad, Iran during April 2006 to March 2016. We used SPSS software, version 16 (SPSS Inc., Chicago, IL, USA) to analyze data. A P value less than 0.05 means that the results are considered statistically significant.
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Results: We included 230 women with breast cancer. The average overall survival was 130.7 months, with 83.2% of people surviving for five years and 78.8% surviving for 10 years. The stage of the disease is strongly linked to the recurrence (P=0.000). Additionally, the specific type of disease is also strongly related to disease recurrence (P=0.01) or metastasis (P=0.01). Patients who have the triple-negative subtype had the highest chance of the cancer spreading and recurrence compared to patients with other subtypes.
Conclusion: The different types of breast cancer are strongly linked to the disease recurrence or metastasis. Patients with triple-negative subtypes had the most cases of cancer spreading to other parts of the body and coming back again, compared to other subtypes. Our findings also showed that patients with the triple-negative disease had the worst overall and disease-free survivals. |
Type of Study: Original Article |
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