Volume 82, Issue 7 (October 2024)
Tehran Univ Med J 2024, 82(7): 553-564 |
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Jan Faza M, Rahimi M R. The effect of eight weeks of physical activity with vitamin D supplementation on endothelial indices in hypertensive patients. Tehran Univ Med J 2024; 82 (7) :553-564
URL: http://tumj.tums.ac.ir/article-1-13225-en.html
URL: http://tumj.tums.ac.ir/article-1-13225-en.html
1- Department of Exercise Physiology, Faculty of Humanities, University of Kurdistan, Sanandaj, Iran. , m.janfaza@urmia.ac.ir
2- Department of Exercise Physiology, Faculty of Humanities, University of Kurdistan, Sanandaj, Iran.
2- Department of Exercise Physiology, Faculty of Humanities, University of Kurdistan, Sanandaj, Iran.
Abstract: (1471 Views)
Background: The aim of our study was to evaluate the effect of 8 weeks of aerobic exercise with vitamin D supplementation on indulin-1 and nitric oxide in patients with hypertension aged 30 to 50 years.
Methods: This study was conducted as a semi-experimental pre-test and post-test design, and was conducted from June 1401 at Seyyed Shohada Hospital in Urmia. 40 eligible men and women were randomly divided into four groups (supplement group, placebo + exercise group, a supplement + exercise group, and a control group). The training program of the experimental groups included eight weeks of aerobic exercise running on a treadmill (3 sessions/8 weeks). Blood sampling to evaluate biochemical variables was performed 48 hours before and after the intervention in a fasting state with a volume of 10 cc.
Methods: This study was conducted as a semi-experimental pre-test and post-test design, and was conducted from June 1401 at Seyyed Shohada Hospital in Urmia. 40 eligible men and women were randomly divided into four groups (supplement group, placebo + exercise group, a supplement + exercise group, and a control group). The training program of the experimental groups included eight weeks of aerobic exercise running on a treadmill (3 sessions/8 weeks). Blood sampling to evaluate biochemical variables was performed 48 hours before and after the intervention in a fasting state with a volume of 10 cc.
| Results: The results of the study show that after 8 weeks of aerobic exercise, vitamin D, BMI, NO, ET-1 and weight were significantly affected (P < 0.05) and systolic blood pressure in the supplement, supplement + exercise and exercise + placebo groups changed compared to the control group(P < 0.05). Conclusion: Based on the results of the present study, the results showed that taking eight weeks of vitamin D supplements along with aerobic activity reduced blood pressure indices in the subjects. Also, taking vitamin D supplements along with physical activity reduced BMI and increased NO, reduced ET-1 and body weight in the subjects in the study. |
Keywords: aerobic exercise, high blood pressure, middle-aged people, nitric oxide, indulin-1, heart and blood vessels, vitamin D.
Type of Study: Original Article |
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