Effect of intravenous immunoglobulin in Guilain-Barre syndrome, myasthenia gravis and chronic idiopathic demyelinative polyneuropathy, A survey in Imam Khomeini Hospital

Qaffarpoor , M

Volume 57, Issue 4 (9 1999) Tehran Univ Med J 1999, 57(4): 57-62 | Back to browse issues page

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Qaffarpoor M. Effect of intravenous immunoglobulin in Guilain-Barre syndrome, myasthenia gravis and chronic idiopathic demyelinative polyneuropathy, A survey in Imam Khomeini Hospital. Tehran Univ Med J 1999; 57 (4) :57-62
URL: http://tumj.tums.ac.ir/article-1-1443-en.html

Effect of intravenous immunoglobulin in Guilain-Barre syndrome, myasthenia gravis and chronic idiopathic demyelinative polyneuropathy, A survey in Imam Khomeini Hospital

M Qaffarpoor ^*

Abstract: (9592 Views)

With retrospective evaluation of 44 patients suffering from Guilan-Barre Syndrome (GBS), Chronic Idiopathic Demtyelinative Polyradiculoneuropathy (CIDP) and Myasthenia Gravis (MG) treated with intravenous immunoglobulin, we found following results: 1) Initial symptoms of improvement on forth or fifth days. 2) Maximum recovery for CIDP and MG were after 16-24 and 3-11 days, respectively. 3) No major complication, but mild side effects in 32% of patients. 4) In patients with GBS one grade improvement achieved after 8-30 days. 5) Intravenous immunoglobulin (IVIG) plus plasmapheresis had no advantages over IVIG alone. 6) No reasonable conclusion about relapsing rate and duration of response due to follow up restrictions.

Keywords: GBS, CIDP, MG

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