Abstract: (6720 Views)
Twenty cases of isolated optic neuritis (15 female, 5 male) were studied and followed for several months to years after the initial attack. The mean age of patients was 23 years (range: 15-29 years). The most frequent clinical manifestations were decreased visual acuity and blurred vision. A complete neurological examination was performed. In 15 cases (75%) the initial brain MRI was abnormal. In fourteen cases, other signs of multiple sclerosis presented in one month to eight years following the initial attack of optic neuritis eleven of the latter cases had an abnormal initial MRI. Acute optic neuritis can be considered a presenting feature of multiple sclerosis, particulary in the presence of an abnormal brain MRI.